Abstract:
:As a result of improved medical services and diagnosis of cystic fibrosis (CF), it has in recent years become clear that this is a common genetic disorder with a worldwide distribution. The average life expectancy of CF patients is very low in the developing world, but in developed countries this fatal childhood disease is becoming a chronic disorder persisting into adult life. In western Europe and North America the average life expectancy is now about 25 years, with a fatal outcome, so that CF represents one of the most serious of inherited life-threatening conditions. It remains to be shown whether very early diagnosis and treatment can further improve the prognosis.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
subject
Has Abstractpub_date
1990-01-01 00:00:00pages
709-15issue
6eissn
0042-9686issn
1564-0604journal_volume
68pub_type
杂志文章abstract::The QBC (quantitative buffy coat) technique was compared with that of the Giemsa-stained thick blood film (GTF) under field conditions in Junlian and Mingshan counties, Sichuan, China, for rapid diagnosis of vivax malaria. Blood samples were collected from 364 volunteer villagers, and each sample was examined with bot...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::A case-control study was conducted in Yaoundé, United Republic of Cameroon, to evaluate the hypothesis that intramuscular inoculations predisposed young children to paralysis if they were later exposed to poliomyelitis virus. Thirty-three cases with lower motor neuron disease and 66 neighbourhood controls were studied...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract:Problem:Slovenia's model of primary health care relied on reactive, episodic care and was ill-equipped to address the country's burden of disease dominated by noncommunicable diseases. Approach:The government has developed a multidisciplinary, community-based, prevention-oriented service delivery model for primary hea...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.19.239616
更新日期:2020-05-01 00:00:00
abstract::In November 1999, Dr Amadou Diarra was appointed senior director of Bristol-Myers Squibb's Secure the Future Initiative. Launched 18 months ago, this public-private partnership is seeking, together with the governments of nine African countries, innovative ways of reducing the transmission and the impact of HIV/AIDS, ...
journal_title:Bulletin of the World Health Organization
pub_type: 面试
doi:
更新日期:2001-01-01 00:00:00
abstract::Intestinal parasitic infections are distributed virtually throughout the world, with high prevalence rates in many regions. Amoebiasis, ascariasis, hookworm infection and trichuriasis are among the ten most common infections in the world. Other parasitic infections such as abdominal angiostrongyliasis, intestinal capi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::The clinical manifestations of acute poisoning by organophosphorus compounds in man are in accord with, initially, the stimulation and, later, the blocking of cholinergic transmission due to acetylcholinesterase inhibition. The manifestations involve mainly the para-sympathetic nerves, the neuromuscular junctions, and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1971-01-01 00:00:00
abstract::A possible method for genetic control of insect vector species involves the use of translocation heterozygotes. The potential of single and double heterozygotes already available in Aedes aegypti has been investigated with computer simulations of release strategies. Such simulations indicate a possible role for transl...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1971-01-01 00:00:00
abstract::A trial of the CHAT, type 1, attenuated poliovirus strain of Koprowski was begun in August 1958 in Léopoldville, a city of 350 000 people, and possessing modern medical facilities, including an institute of public health.Paralytic poliomyelitis is endemic in the city; since 1951 there has been an average annual incide...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1960-01-01 00:00:00
abstract::This article surveys the attitudes and perceptions of a random sample of the elderly population in three regions of Italy on the use and efficacy of influenza vaccine. The data were collected by direct interviews using a standard questionnaire. The results show that vaccination coverage against influenza is inadequate...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::This paper examines two innovative educational initiatives for the Ecuadorian public health workforce: a Canadian-funded Masters programme in ecosystem approaches to health that focuses on building capacity to manage environmental health risks sustainably; and the training of Ecuadorians at the Latin American School o...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.07.045393
更新日期:2009-04-01 00:00:00
abstract::Data on the dynamics of the tuberculosis situation in rural South India, obtained by the National Tuberculosis Institute, Bangalore, were fed into a mathematical model. By this means predictions about the future tuberculosis situation have been made under a wide range of hypothetical assumptions. ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00
abstract::Quantitative data are presented on the viability of El Tor vibrios in various foodstuffs under different conditions. El Tor vibrios were found to have a very short life in water at -20 degrees C, but in various nutrient media, such as skim milk, sugar solution or meat extract, they could live for more than a month at ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::International health policy-makers now have a variety of institutional instruments with which to pursue their global and national health goals. These instruments range from the established formal multilateral organizations of the United Nations to the newer restricted-membership institutions of the Group of Eight (G8)...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.06.039917
更新日期:2007-03-01 00:00:00
abstract::Three experiments were carried out in field cages to test the principle of "transport" of a desirable gene or chromosome into a wild Culex fatigans population as a result of the sterility in cross-matings associated with cytoplasmic incompatibility. Cycling populations of Delhi origin were established in the cages and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Four cases of Plasmodium ovale malaria are reported among US servicemen stationed in Viet-Nam between January 1966 and March 1969. Taken together with other cases cited by the authors, these provide strong evidence of the existence (sometimes disputed) of this Plasmodium in continental South-East Asia.None of the men ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1970-01-01 00:00:00
abstract::A dengue type 1 epidemic occurred in Fiji between July 1989 and July 1990. Virus isolation in C6/36 cell cultures and Toxorhynchites mosquitos yielded 36 strains. Of the 3686 cases recorded by the Ministry of Health, 60% involved indigenous Fijians and 37%, Indians. A house-to-house survey revealed that a large majori...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Two, 30-cluster, retrospective surveys of deaths from neonatal tetanus in Indonesia were conducted during 1982. The first survey, in the city of Jakarta, identified 16 deaths from neonatal tetanus among 2310 live births, giving a mortality rate of 6.9 per 1000 live births. The second survey covered 19 of Indonesia's 2...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:To develop a Bayesian hierarchical model for human onchocerciasis with which to explore the factors that influence prevalence of microfilariae in the Amazonian focus of onchocerciasis and predict the probability of any community being at least mesoendemic (>20% prevalence of microfilariae), and thus in need o...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::This month the World Health Assembly discusses the post-2015 global tuberculosis strategy and accompanying set of targets. Giovanni Battista Migliori tells Fiona Fleck how his institute - one of WHO's thousands of partners across the globe - can contribute in future to its implementation, once it is approved. ...
journal_title:Bulletin of the World Health Organization
pub_type: 面试,新闻
doi:10.2471/BLT.14.030514
更新日期:2014-05-01 00:00:00
abstract::In this paper an analysis of genetic recombinants derived from crosses between two mutant stocks of Vibrio cholerae, strain 162, differing from one another in nutritional requirements and other characters, is presented. It is shown that parent strains possessing a fertility factor (designated as the P factor) function...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of treatment for hepatitis C virus (HCV) infection in low- and middle-income countries and identify factors associated with successful outcomes. METHODS:We performed a systematic review and meta-analysis of studies of HCV treatment programmes in low- and middle-income countries. T...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,meta分析,评审
doi:10.2471/BLT.11.097147
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of violence against mothers on mortality risks for their offspring before 5 years of age in Nicaragua. METHODS:From a demographic database covering a random sample of urban and rural households in Le n, Nicaragua, we identified all live births among women aged 15-49 years. Cases wer...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::In the past, several indices have been proposed to evaluate the threat of vectors to the community. Such indices, if accurately determined, could serve to assess the effectiveness of vector control campaigns. In this paper, a "risk of infection" index is introduced for the case of urban filariasis transmitted by Culex...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::The frequent experience in the tropics of poor results of BCG vaccination is sometimes explained by a hypothetical interaction with "non-specific" tuberculin sensitivity. However, samples of data from five tropical countries, reported in this paper, demonstrate a slight, positive correlation between the individual tub...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1966-01-01 00:00:00
abstract::Presented is an assessment of the cost-effectiveness of cataract surgery using cost and services data from the Lumbini Zonal Eye Care Programme in Nepal. The analysis suggests that cataract surgery may be even more cost-effective than previously reported. Under a "best estimate" scenario, cataract surgery had a cost o...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::This report concerns the host's reactions to the presence of the parasite both in the course of the natural disease and during drug treatment. The various stages of Onchocerca volvulus are discussed in terms of the type of tissue reaction seen. The discussion then turns to basic hypotheses concerning the etiology of t...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Uruguay is hosting the WHO Global Conference on Noncommunicable Diseases (NCDs) this month, from 18-20 October. Tabaré Vázquez, the President of Uruguay, tells the Bulletin of the World Health Organization about his country's efforts to prevent and fight NCDs and why countries should step up the global response. ...
journal_title:Bulletin of the World Health Organization
pub_type: 新闻
doi:10.2471/BLT.17.031017
更新日期:2017-10-01 00:00:00
abstract::Israel has faced the challenge presented by epidemic poliomyelitis by using different immunization strategies. In the 1950s, inactivated poliovirus vaccine (IPV) helped to reduce the total burden of the disease, but cases continued to occur. Introduction of oral poliovirus vaccine (OPV) in mid-1961 had a dramatic effe...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::Evaluation of disease outcome is central to the assessment of tuberculosis (TB) control programmes. In the study reported in this article we examined the factors influencing the measurement of outcome, survival rates during and after treatment, smear conversion rates, and relapse rates for patients diagnosed with TB i...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::One of the hazards involved in the use of antibiotics in animal feeds is that it may lead to the development of bacterial drug-resistance. An analysis of the phenomenon shows that this possibility largely depends on the size of the bacterial populations involved and on the possibility of selective multiplication of th...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1963-01-01 00:00:00