Abstract：
:Cells require a sensory system and a motility structure to achieve directed movement. Bacteria and archaea possess rotating filamentous motility structures that work in concert with the sensory chemotaxis system. This allows microorganisms to move along chemical gradients. The central response regulator protein CheY can bind to the motor of the motility structure, the flagellum in bacteria, and the archaellum in archaea. Both motility structures have a fundamentally different protein composition and structural organization. Yet, both systems receive input from the chemotaxis system. So far, it was unknown how the signal is transferred from the archaeal CheY to the archaellum motor to initiate motor switching. We applied a fluorescent microscopy approach in the model euryarchaeon Haloferax volcanii and shed light on the sequence order in which signals are transferred from the chemotaxis system to the archaellum. Our findings indicate that the euryarchaeal-specific ArlCDE are part of the archaellum motor and that they directly receive input from the chemotaxis system via the adaptor protein CheF. Hence, ArlCDE are an important feature of the archaellum of euryarchaea, are essential for signal transduction during chemotaxis and represent the archaeal switch complex.
journal_name
Mol Microbioljournal_title
Molecular microbiologyauthors
Li Z,Rodriguez-Franco M,Albers SV,Quax TEFdoi
10.1111/mmi.14527subject
Has Abstractpub_date
2020-09-01 00:00:00pages
468-479issue
3eissn
0950-382Xissn
1365-2958journal_volume
114pub_type
杂志文章abstract：:To identify Rhodobacter capsulatus nif genes necessary for the alternative nitrogenase, strains carrying defined mutations in 32 genes and open reading frames of nif region A, B or C were constructed. The ability of these mutants to grow on nitrogen-free medium with molybdenum (Nif phenotype) or in a nifHDK deletion b...
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更新日期：1993-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：1998-02-01 00:00:00
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更新日期：2006-08-01 00:00:00
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