Abstract：
BACKGROUND AND PURPOSE:The aim was to conduct a pilot study of selected epidemiological aspects of multiple sclerosis (MS) in Poland. MATERIAL AND METHODS:Cross-sectional data were collected in 21 centres providing MS treatment. The demographic profile of the patients, medical history of MS, disability status, comorbidity, and diagnostic and treatment modalities were analysed. RESULTS:Data on 3581 patients were obtained, including 2494 women (69.6%) and 1030 men (28.8%) - sex ratio 2.4 : 1. The mean age was 40.7 ± 11.9 years. Monofocal onset was reported in 80.8% of cases - the most frequently reported location of lesions was supratentorial (36.1%), followed by optic nerves (26.5%) and spinal cord (20.1%). The mean disease duration was 10.2 ± 8.8 years (range 0.04-53 years), and the mean time from the first symptoms to MS diagnosis was 2.6 years. Relapsing-remitting MS was reported in 70.5% of patients, secondary progressive in 16.8%, primary progressive in 8.4%, and 'benign MS' in 2.5%. The mean EDSS score was 3.3 ± 2.2 (range 0-9.5). The family history of MS was positive in 6.4% of cases. Comorbidity mainly applied to the musculoskeletal system (6.5%), the urinary system (5.8%) and psychiatric disturbances (5.5%). Brain magnetic resonance studies were available in 96.3% of the patients, evoked potentials in 54%, and cerebrospinal fluid testing in 63.1% - of whom only 41.2% were tested for oligoclonal bands, with 84% of samples being positive. Immunomodulatory drugs were used in 842 patients (24%), predominantly interferon beta (81%) and glatiramer (13%). Mitoxantrone was the most commonly used immunosuppressant. CONCLUSIONS:This project is the first countrywide large-scale MS survey, covering approximately 18% of patients, according to our estimates. The results identify the clinical condition of the patients, as well as diagnostic and treatment modalities.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Kułakowska A,Bartosik-Psujek H,Hożejowski R,Mitosek-Szewczyk K,Drozdowski W,Stelmasiak Zdoi
10.1016/s0028-3843(14)60134-1subject
Has Abstractpub_date
2010-09-01 00:00:00pages
443-52issue
5eissn
0028-3843issn
1897-4260pii
S0028-3843(14)60134-1journal_volume
44pub_type
杂志文章,多中心研究abstract：:The pathology, clinical course, outcome, diagnosis, treatment and prognosis of dramatic malignant middle cerebral artery territory infarction were presented. About 10% of stroke patients suffer from malignant middle cerebral artery territory infarction, mainly due to brain edema and herniation. This syndrome causes hi...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-09-01 00:00:00
abstract：:The clinical aspects of volume-pressure relations and their disturbances are presented with description of acute and chronic changes after intracranial lesions and various physiological situations. The diagnostic methods which are applied for the assessment of intracranial volume-pressure relations are discussed. A me...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1991-09-01 00:00:00
abstract：:The authors present four cases of acute epidural hematoma (three supratentorial and one in the posterior fossa), in which non-operative treatment was performed. The conditions to undertake this treatment were: good clinical and neurological state of the patients on admission (GCS equal or more than 14), absence or mil...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：:The authors present a case of Huntington disease in a 14 year old boy. The basis of genetic, pathoetiology, clinical course of disease, significance of molecular analysis of DNA are discussed. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND AND PURPOSE:According to the World Health Organization (WHO) assumptions every patient with a stroke should be treated by a specialized stroke team or in a specialized stroke unit. The aim of our study was to evaluate the accessibility and eligibility of stroke units in Poland. MATERIALS AND METHODS:We have...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：:The authors report the results of surgical treatment of 11 patients with carpal tunnel syndrome. The group comprised 10 women and 1 man. In 4 cases bilateral symptoms were present. The duration of the disease was from 6 months to 10 years (mean 4.2 years). In all patients operation was followed by complete disappearan...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:In 48 patients the acid-base equilibrium in the CSF and blood was determined on the 2nd day after intracranial operation. In the postopertive period various disturbances of this equilibrium were found which were probably various stages of metabolic acidosis compensation in the CSF which was a reflection of metabolic (...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1975-07-01 00:00:00
abstract：:Thanks to endocrinological and radiological diagnostic improvement and development of pituitary adenoma neurosurgery, CT-examination became a routine examination in such cases, in selected situations supported with MRI-examination. The authors report a short bibliography review of radiologically difficult cases, expla...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1991-09-01 00:00:00
abstract：INTRODUCTION:Tremor is the most prevalent movement disorder, defined as rhythmic oscillations of a body part, caused by alternating or synchronic contractions of agonistic or antagonistic muscles. The aim of the study was to assess prevalence and to characterize parameters of tremor accompanying de-generative ataxias, ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.5114/ninp.2013.35585
更新日期：2013-05-01 00:00:00
abstract：:Peripheral facial paresis is a serious clinical and social problem. The effect of physical therapy in 44 patients aged 13-80 was studied. Idiopathic peripheral facial paresis was the cause of mimic muscles dysfunction in 75% of our patients. Medical treatment was conducted according to the established program, consist...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Experimental studies of different stroke models equivocally showed that hyperglycaemia is responsible for the increase of infarct volume and mortality. Similar results were obtained in several, but not all clinical studies. The aim of the study was to assess the occurrence and prognosis of transient hyperglycaemia in ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:Adrenoleukodystrophy (ALD) is a hereditary disease related to abnormalities in the structure and function of peroxisomes. The nature of disorder arises from defective process of beta-oxidation of very-long-chain fatty acids and their accumulation in various organs. ALD may present as a few phenotypes urologic symptoma...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：:A group of 50 epileptics (group C) with frequent seizures refractory to treatment was studied. The control group (R) comprised 50 cases with rare seizures. It was found that despite systematic treatment (with full therapeutic doses) and frequent changes of drugs the frequency of seizures was not reduced in group C. Th...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：:In a retrospective study of diabetic and non-diabetic patients with acute ischaemic stroke, mortality and neurological outcome were assessed. Mortality was determined 4 weeks after admission. The study population consisted of the consecutive patients (n = 609) admitted to the Department of Neurology with acute stroke ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:The authors conducted periodic electroencephalographic (chrono-EEG) investigations in 64 subjects including 48 with various vasomotor headaches and 16 healthy ones. Chrono-EEG investigations carried out at different times of the day during wakefulness in healthy subjects and patients with Horton's (cluster) headaches ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:The authors analysed 95 SEEG records in epileptics with prevalent temporal-lobe changes comparing the bioelectric activity of the brain recorded simultaneously in the amygdala, hippocampus, temporal cortex and cranial surface during these investigations and relating them to EEG records obtained before the operation. I...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:The authors discuss a case of a 46 year-old man with bilateral internal carotid artery and right vertebral artery occlusion in unexpectedly good clinical state. The clinical diagnosis is documented by angiographic and doppler findings and brain CT scan. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:The authors report a case of conservatively cured abscess in the left cerebellar hemisphere demonstrated by CT. The patient was admitted in serious condition to a neurotraumatology centre. After pharmacological treatment a quick improvement of patient's health was achieved and control CT examination during his stay in...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Follow-up examinations are reported of 218 patients with a history of reversible ischaemic stroke. The examinations were carried out 4 years after the onset of the disease which led to first hospitalization (1984-1987). It was possible to determine the frequency of repeated ischaemic episodes which developed in 27.5% ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
abstract：:Cortico-basal degeneration (CBD) or cortico-basal ganglionic degeneration is a condition characterised by selective cortical atrophy of parietal and in a lesser extent, frontal lobe associated with dysfunction of the basal ganglia. The clinical symptoms of CBD, predominantly extrapyramidal signs (bradykinesia and rigi...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:Endocarditis is an infectious and inflammatory disease of cardiac valves with other coexisting symptoms affecting heart and other organs and systems. Patients with cardiac valves diseases are in the group of high risk. The authors present a case of successfully treated endocarditis affecting mitral valve prosthesis in...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：:From a group of 248 cases of epilepsy observed in the last five years 69 (28%) children, 32 boys and 37 girls, were isolated (aged from several months to 14 years) in whom the first epileptic seizures appeared at the age of 3 years or less. The subgroups were subjected to detailed psychiatric-psychological analysis fo...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Diabetes mellitus (DM) is an in-dependent risk factor for cardiovascular diseases. The origin of diabetic microangiopathy is multifactorial; it affects all layers of the artery wall, causing endothelial and vasoreactivity impairment. The incidence of cerebral vasoreactivity failure in diabetic pa...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.5114/ninp.2012.32175
更新日期：2012-11-01 00:00:00
abstract：:A man aged 51 developed signs of damage to the inferior part of the thoracic cord and lumbosacral cord due to a dissecting aneurysm of the abdominal aorta. The aneurysm was demonstrated by USG and CT investigations of the abdomen. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：:A 54-year-old male patient is reported in whom progression of clinical manifestations, neurological signs and results of ancillary investigations suggested a cerebellopontine angle tumour in the initial stage of the disease. Further observation and additional appearance after 10 months of signs evidencing damage to ot...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:In the years 1969-1986 operations were carried out in 1650 cases of lateral prolapse of the lumbar nucleus pulposus at one level, they accounted for 75% of patients operated on for symptomatic sciatic pains. The operations were done in lateral recumbent position. In 29% of cases it was necessary to extend the typical ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1987-05-01 00:00:00
abstract：:Visual evoked potentials in response to checkerboard reversal pattern were evaluated in 160 patients: 24 with isolated retrobulbar optic neuritis, 100 with unquestionable and probable multiple sclerosis, 36 with paraparesis or with disseminated changes of unestablished aetiology (degenerative or inflammatory) and in 8...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：:The author describes a 47-year-old patient in whom lingual hemiatrophy developed one month after angina. The development of hemiatrophy was preceded by occipital headaches and pain behind the ear on the side of hemiatrophy. In the differential diagnosis the author excluded inflammatory processes neoplasms and developm...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：:In 62 women the course of epilepsy was analysed at the age of puberty from 11 to 15 years of life. In 19 cases the course of the disease remained unchanged at that time, in 20 cases the seizures disappeared or became less frequent, in 20 cases the frequency of seizures increased, other types of seizures developed, or ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1975-09-01 00:00:00
abstract：:The studied material comprised 280 patients hospitalized for the first time for reversible ischaemic neurological deficit. The clinical condition of the patients, the incidence of hypertension (48.3%), ischaemic heart disease (36.4%) and diabetes (4.3%) was assessed and the indices were calculated of first admissions ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
