Abstract:
BACKGROUND AND PURPOSE:Diabetes mellitus (DM) is an in-dependent risk factor for cardiovascular diseases. The origin of diabetic microangiopathy is multifactorial; it affects all layers of the artery wall, causing endothelial and vasoreactivity impairment. The incidence of cerebral vasoreactivity failure in diabetic patients without stroke history is not precisely determined yet. The aim of the study was to assess the cerebrovascular reactivity in hypocapnia and hypercapnia in patients with type 2 DM with or without arterial hypertension without artery stenosis and stroke history, with the use of transcranial Doppler examination. MATERIAL AND METHODS:The mean blood flow velocity, pulsatility index and parameters of cerebrovascular reactivity were measured in 53 patients with type 2 DM (aged 42-72 years, mean 59.5 ± 7.9) and in 27 healthy volunteers (aged 36- 74 years, mean 57.0 ± 10.4). Diabetics were further divided into two subgroups according to the presence or absence of arterial hypertension. RESULTS:The index of cerebrovascular reactivity in hypocapnia and hypercapnia was significantly worse and time needed to normalization of blood flow velocity was significantly longer in patients with DM in comparison with healthy volunteers. CONCLUSIONS:Most DM type 2 patients without stroke history had decreased values of cerebral vasoreactivity parameters, which suggests the presence of microangiopathy.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Lasek-Bal A,Kazibutowska Z,Gołba A,Motta Edoi
10.5114/ninp.2012.32175subject
Has Abstractpub_date
2012-11-01 00:00:00pages
529-35issue
6eissn
0028-3843issn
1897-4260pii
S0028-3843(14)60251-6journal_volume
46pub_type
杂志文章abstract:BACKGROUND AND PURPOSE:Endovascular embolization is an approved method of treatment of cerebral aneurysms. Several difficulties can be caused by wide-neck aneurysms. In these cases vascular remodelling is required. It can be performed with the use of balloons or intracranial stents. This method allows expansion of the ...
journal_title:Neurologia i neurochirurgia polska
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abstract:BACKGROUND:The efficacy and safety of thrombolytic therapy in stroke depend on multiple factors. The aim of this study was to evaluate the significance of atrial fibrillation the prognosis in terms of the functional status in patients with stroke treated with intravenous thrombolysis. An additional aim was also to asse...
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journal_title:Neurologia i neurochirurgia polska
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abstract::Peripheral facial paresis is a serious clinical and social problem. The effect of physical therapy in 44 patients aged 13-80 was studied. Idiopathic peripheral facial paresis was the cause of mimic muscles dysfunction in 75% of our patients. Medical treatment was conducted according to the established program, consist...
journal_title:Neurologia i neurochirurgia polska
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abstract::The problem of pathogenesis and effective treatment of traumatic optic neuropathy (TON) is still an open question. According to current opinions the immediate results of conservative treatment with megadose corticosteroids are similar to those obtained with surgical decompression. No data on late results of both modes...
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abstract::Marchiafava-Bignami disease (MBD) is a rare fatal neurological disorder characterized by demyelination, primary degeneration, and necrosis of the corpus callosum. Although MBD is mostly associated with chronic alcohol consumption and malnutrition, it has been reported in non-alcoholic patients. Serotonin syndrome is a...
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journal_title:Neurologia i neurochirurgia polska
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abstract:BACKGROUND AND PURPOSE:Migraine is a common neurologic disorder whose etiology remains unknown. Migraine has been reported as a possible risk factor for ischemic stroke, especially in young women. The relationship between migraine and stroke is stronger in patients suffering from migraine with aura compared to those wi...
journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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doi:
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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abstract::The pathological mechanism of pain in vertebral column diseases is discussed in accordance with the theory of Melzack and Wall taking into account both systems of pain sensation control at the spinal level and reticular formation level. The action of pain mediators is discussed as well. The main pathogenetic factors a...
journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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doi:
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