Abstract:
:As donation after cardiac death practices expand, the number of institutional policies is increasing. We contacted organ procurement organizations throughout the United States and requested protocols in hospitals in their donor service areas. Sixty-four protocols were obtained with representation from 16 different states. The terminology and recommended practices varied substantially. The methods for death determination were not specified in 28 (44%) protocols. Most adhered to a 2- to 5-min observation time between circulatory arrest and organ procurement, but 10 (16%) provided no information. This variability reveals a need to define a uniform standard in donation after cardiac death protocols and death determination practices.
journal_name
Transplantationjournal_title
Transplantationauthors
Fugate JE,Stadtler M,Rabinstein AA,Wijdicks EFdoi
10.1097/TP.0b013e318204ee96subject
Has Abstractpub_date
2011-02-27 00:00:00pages
386-9issue
4eissn
0041-1337issn
1534-6080journal_volume
91pub_type
杂志文章相关文献
TRANSPLANTATION文献大全abstract:BACKGROUND:Persistent massive ascites (PMAS) longer than 14 days after living donor liver transplantation is not uncommon and associated with worse outcome. A predictive risk scoring system was constructed after analysis of recipient, graft, and surgery-related factors. METHODS:We retrospectively reviewed adult living...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/TP.0000000000002174
更新日期:2018-06-01 00:00:00
abstract::A major impediment to the wider application of clinical liver transplantation is the paucity of acceptable organs. Most centers refuse organs that come from donors who are hepatitis B core antibody positive because of a fear of transmission of hepatitis B virus (HBV) infection to the recipient. The risk related to the...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-199908270-00013
更新日期:1999-08-27 00:00:00
abstract:BACKGROUND:FK506-binding proteins (FKBP) are immunophilins that interact with the immunosuppressive drugs FK506 and rapamycin. Several FKBP family members such as FKBP12, FKBP12.6, and FKBP51 are expressed in T cells. It has been speculated that these FKBPs are possibly redundant in the immunosuppressant-induced T-cell...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-200206150-00023
更新日期:2002-06-15 00:00:00
abstract::P-31 nuclear magnetic resonance (NMR) spectroscopy was used to evaluate heterotropic cardiac allograft rejection in the rat. To enable optimal application of NMR spectroscopy for the in vivo study of myocardial metabolism in the transplanted organ, an accessory heart transplantation to groin in the rat was used. The a...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-198708000-00002
更新日期:1987-08-01 00:00:00
abstract::Adult bone marrow-derived mesenchymal stem cells (MSCs) are multipotential cells capable of regenerating injured tissues. In addition to their multipotency, MSCs inhibit natural killer cell cytotoxicity and T-lymphocyte alloproliferation. Several immunosuppressive mechanisms have been described, including indoleamine ...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/TP.0b013e3181a2a4b3
更新日期:2009-05-15 00:00:00
abstract::Renal allografts were performed in miniature swine that were identical at their major histocompatibility locus and were presensitized by skin grafts from their prospective renal donors. All of these renal grafts were rejected in a hyperacute or markedly accelerated manner compared to the survival of comparable grafts ...
journal_title:Transplantation
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract::Sixty-two adults who underwent orthotopic liver transplantations between February 1981 and June 1983 were followed for a mean of 170 days after the operation. Twenty-six patients developed 30 episodes of significant fungal infection. Candida species and Torulopsis glabrata were responsible for 22 episodes and Aspergil...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-198510000-00002
更新日期:1985-10-01 00:00:00
abstract:BACKGROUND:Pneumocystis jiroveci pneumonia may be a life-threatening opportunistic infection in immunosuppressed solid organ transplant recipients. Despite effective treatment with high-dose trimethoprim-sulfamethoxazole and steroids, morbidity is often severe and lethality remains high. New therapeutic approaches are ...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/01.tp.0000280546.91617.6c
更新日期:2007-09-27 00:00:00
abstract::Potential female donors frequently ask whether unilateral nephrectomy will impair future childbearing capabilities. To address this question, we surveyed 220 women who underwent donor nephrectomy between 1985 and 1992. Of the 144 women who responded, 33 became pregnant after donation for a total of 45 pregnancies. Sev...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-199612270-00044
更新日期:1996-12-27 00:00:00
abstract:BACKGROUND:We have reported the protective role of heme oxygenase-1 (HO-1) in the mechanism of hypoxic preconditioning. We wish to investigate the role of HO-1 in remote preconditioning (RP) against hepatic ischemia/reperfusion (I/R) injury in rats. METHODS:The remote preconditioning was produced by four cycles of 10-...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/01.tp.0000203555.14546.63
更新日期:2006-05-15 00:00:00
abstract:BACKGROUND:Chronic cyclosporine (CsA) nephropathy, which has been unequivocally documented in recipients of heart, heart-lung, liver, or bone marrow transplants, as well as in nontransplant situations, usually results in a progressive deterioration of renal function. In this study, we assessed the potential reversibili...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-199803150-00010
更新日期:1998-03-15 00:00:00
abstract::Donation physicians are specialists with expertise in organ and tissue donation and have been recognized internationally as a key contributor to improving organ and tissue donation services. Subsequent to a 2011 Canadian Critical Care Society-Canadian Blood Services consultation, the donation physician role has been g...
journal_title:Transplantation
pub_type: 杂志文章,实务指引
doi:10.1097/TP.0000000000001694
更新日期:2017-05-01 00:00:00
abstract::Two anti-H-2Ld sera were analyzed, BALB/c-H-2dm2 anti-BALB/cBy and (C3H X BALB/c-H-2dm2)F1 anti-BALB/cHe, the latter also containing anti-Qa antibodies. Their reaction patterns were compared with an anti-Qa serum (C3H X BALB/cBy)F1 anti-BALB/cHe. Four H-2 specificities could be detected by the anti-H-2Ld sera, two alr...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-198108000-00009
更新日期:1981-08-01 00:00:00
abstract::The results of kidney retransplantation in the cyclosporine era remain to be determined. Over a 42-month period, 76 nonprimary renal transplants (66 second, 7 third, 3 fourth allografts) were performed in 73 recipients under cyclosporine immunosuppression. The patient population was predominantly white (90.4%) with a ...
journal_title:Transplantation
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:A new supercooling system using a variable magnetic field has been recently developed. Subzero nonfreezing preservation has been believed to be a beneficial method because of the lower metabolic rate. The purpose of this study was to evaluate the hemodynamic and metabolic effects of rat heart preservation in...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/TP.0b013e3182637054
更新日期:2012-09-15 00:00:00
abstract:BACKGROUND:Prolonged persistence of donor-derived T cells after organ transplantation has been proposed to improve long-term allograft survival. However, surviving transplant-derived T cells are also able to mediate devastating graft-versus-host disease (GvHD). Currently, GvHD after organ transplantation is usually ref...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/01.tp.0000144183.77279.ec
更新日期:2004-12-27 00:00:00
abstract:BACKGROUND:Orthotopic liver transplantation (OLT) has been associated with major blood loss and the need for blood product transfusions. During the last decade, improved surgical and anesthetic management has reduced intraoperative blood loss and blood product transfusions. A first report from our group published in 20...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/TP.0b013e318250fc25
更新日期:2012-06-27 00:00:00
abstract::Pulmonary thrombus formation in the region of atrial anastomosis following lung transplantation has been reported by several authors. Such patients typically present immediately after surgery with significant hemodynamic compromise causing pulmonary edema and hypoxemia. We describe a patient who presented with bilater...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-199609150-00028
更新日期:1996-09-15 00:00:00
abstract::Mice immunized with allogeneic cells exhibit a local component of cellular immunity that is confined to lymph nodes draining the site of immunization. After immunization of C3H mice by skin grafting or by i.p. or footpad injection of F1 hybrid spleen cells, draining lymph nodes show increased responsiveness toward the...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-198107000-00006
更新日期:1981-07-01 00:00:00
abstract:BACKGROUND:Treatment of chronic hepatitis C virus (HCV) infection after renal allograft transplantation has been an obstacle because of contraindications associated with IFN-based therapies. Direct-acting antiviral agents are highly efficient treatment options that do not require IFN and may not require ribavirin. Ther...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/TP.0000000000001414
更新日期:2017-05-01 00:00:00
abstract::A rapid microcytotoxicity assay for the detection of HL-A antigens on tissue culture cells derived from human solid tumors is described. Tumor cells were prelabeled with 125Iododeoxyuridine. Isotopically labeled tumor cells were reacted with up to 37 highly selected HL-A antisera and diluted rabbit complement. Results...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-197509000-00005
更新日期:1975-09-01 00:00:00
abstract::Most patients with secondary hypertension due to renal disease or on maintenance hemodialysis have lost the physiologic fall of blood pressure during sleep. To test the notion that kidney transplantation normalizes the blood pressure profile, we monitored ambulatory blood pressure over 24 hr in 45 patients (29 males a...
journal_title:Transplantation
pub_type: 杂志文章
doi:
更新日期:1995-05-15 00:00:00
abstract::The mode of action of glucocorticosteroids as immunosuppressive and antiinflammatory agents is not fully understood. Glucocorticosteroids block synthesis of interleukin 1 by interfering with the transcription of the IL-1 beta gene. Glucocorticosteroids may also induce rapid degradation of IL-1 mRNA. In the presence of...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-199001000-00040
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:CTLA4IgG that binds to B7 effectively inhibits the signaling of CD28/B7 pathway and induces antigen-specific T-cell unresponsiveness in vitro and in vivo. We examined whether the development of obliterative bronchiolitis in a murine heterotopic airway transplantation model is T cell dependent and whether CTL...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-200003150-00012
更新日期:2000-03-15 00:00:00
abstract::The improvement of graft survival over the past decade has mainly been due to the development of more highly specific immunosuppressive agents, such as cyclosporine (CsA) and FK506. CsA and FK506 inhibit T cell activation by interfering with the calcium-mediated pathway, one of two pathways needed for T cell activatio...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-199606150-00015
更新日期:1996-06-15 00:00:00
abstract::Human herpesvirus type 6 (HHV-6) causes roseola infantum (exanthema subitum) upon primary infection in young children. Thereafter it persists lifelong in the organism. Like other herpesviruses, HHV-6 can be reactivated in periods of immunosuppression - e.g., after organ transplantation. In order to study the incidence...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-199602270-00027
更新日期:1996-02-27 00:00:00
abstract:BACKGROUND:Evidence on prevalence and correlates of pretransplant medication nonadherence (MNA) is limited. The present study explored self-reported prevalence and correlates of MNA before heart, liver, and lung transplantation. METHODS:This cross-sectional descriptive study included 174 patients: 69 lung, 33 heart, a...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/01.tp.0000158430.06507.87
更新日期:2005-06-15 00:00:00
abstract:BACKGROUND:The deleterious effect of steatosis on transplanted livers is mainly related to a microcirculation impairment. We investigated the effect of preservation duration on the recovery of isolated perfused rat steatotic livers and tested the effect of pentoxifylline (PTX), known to have a beneficial effect on hepa...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/01.TP.0000071846.35825.B1
更新日期:2003-07-15 00:00:00
abstract::Monoclonal antibodies to CD3 have been shown to activate T cells in vivo and in vitro but have also been shown to render T cells anergic in vitro. In this study G4.18, a mouse IgG3 mAb, was produced that appeared to recognize CD3 by its binding to all peripheral T cells, including a population not recognized by mAb to...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/00007890-199303000-00001
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:In response to a longstanding Federal mandate to minimize the role of geography in access to transplant in the United States, we assessed whether patient travel distance was associated with lung transplant outcomes. We focused on the posttransplant time period, when the majority of patient visits to a transp...
journal_title:Transplantation
pub_type: 杂志文章
doi:10.1097/TP.0000000000003129
更新日期:2020-11-01 00:00:00