Successful Pregnancy after Intervention for Spindle-Cell Embryonal Rhabdomyosarcoma: A Case Report.

Abstract:

BACKGROUND:Embryonal rhabdomyosarcoma, the most common soft tissue malignancy in childhood, is treated with surgery and chemotherapy. Because of the young age at the time of presentation, a discussion of future reproduction is appropriate and conservative management should be considered. We present a case of embryonal rhabdomyosarcoma that was successfully and conservatively managed with chemotherapy, allowing for future pregnancies. CASE:A 17-year-old nulliparous woman with embryonal rhabdomyosarcoma underwent 6 cycles of chemotherapy with adriamycin, dacarbazine, cyclophosphamide, and vincristine, resulting in radiographic resolution of the disease. She was able to conceive without medical intervention and to have successful vaginal deliveries. SUMMARY AND CONCLUSION:The standard of care for embryonal rhabdomyosarcoma is surgery and chemotherapy; however, conservative management should be considered when preservation of fertility is a goal.

authors

Moufarrij SM,Edwards C,McKenzie L,Adeyemi-Fowode O

doi

10.1016/j.jpag.2020.03.004

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

613-615

issue

5

eissn

1083-3188

issn

1873-4332

pii

S1083-3188(20)30194-7

journal_volume

33

pub_type

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