Hepatic ischemia reperfusion injury: Contemporary perspectives on pathogenic mechanisms and basis for hepatoprotection-the good, bad and deadly.

abstract：BACKGROUND:There are few detailed clinical reports about extrahepatic metastases of hepatocellular carcinoma (HCC). The purpose of the present study was to elucidate the clinical features of extrahepatic metastases of HCC. METHODS:The clinical records of 482 patients who had been diagnosed as having HCC during the per...

journal_title：Journal of gastroenterology and hepatology

authors： Natsuizaka M,Omura T,Akaike T,Kuwata Y,Yamazaki K,Sato T,Karino Y,Toyota J,Suga T,Asaka M

更新日期：2005-11-01 00:00:00

abstract：:Here we identify a previously unreported cause of rectal bleeding (juvenile polyposis) in a patient with cystic fibrosis (CF). We believe this patient most likely has two coexisting genetic diseases. It also raises many issues about organ transplantation in a patient with medical conditions that individually increase ...

journal_title：Journal of gastroenterology and hepatology

authors： Treepongkaruna S,Hardikar W,Chow CW,Smith AL,Oliver MR

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Although there is strong implication that retinoids regulate Ito cell proliferation and collagen synthesis, results from in vivo studies on the relationship between vitamin A and liver fibrosis are conflicting. The present study focuses on the role of vitamin A in carbon tetrachloride (CCl4)-induced fibrosis...

journal_title：Journal of gastroenterology and hepatology

authors： Vollmar B,Heckmann C,Richter S,Menger MD

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND AIM:The activation of Rho proteins has been shown to lead to loss of polarity in cancer cells, as well as reorganization of the cytoskeleton and facilitation of cell motility, possibly resulting in their malignant potential. The clinicopathological significance of RhoA, however, is not yet well known in ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang D,Dou K,Xiang H,Song Z,Zhao Q,Chen Y,Li Y

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND AIM:Although several molecular biomarkers for esophageal adenocarcinoma (EAC) have been shown to be useful disease indicators, none has been established as a reliable indicator for risk of EAC or have progressed to routine use. The aim was to identify biomarkers of high risk for EAC in patients with Barr...

journal_title：Journal of gastroenterology and hepatology

authors： Murao T,Shiotani A,Fujita Y,Yamanaka Y,Kamada T,Manabe N,Hata J,Nishio K,Haruma K

更新日期：2016-01-01 00:00:00

abstract：:Patients with Crohn's disease of the distal ileum show increased permeability to hyaluronan and increased release of histamine and complement components in uninvolved parts of the proximal jejunum. These abnormalities are related to disease activity, and are not found in first-degree relatives. Increased synthesis of ...

journal_title：Journal of gastroenterology and hepatology

authors： Ahrenstedt O,Hällgren R,Knutson L

更新日期：1994-11-01 00:00:00

abstract：:In order to achieve possible greater therapeutic efficacy, ranitidine 300 mg bid (R2) may be given rather than 300 mg qhs (R1), or nizatidine 300 mg bid (N2) may be given rather than 300 mg qhs (N1). A randomized placebo-controlled crossover study was performed in six healthy volunteers (four males, two females) who r...

journal_title：Journal of gastroenterology and hepatology

authors： Thompson A,Kirdeikis P,Jamali F,Tavernini M,Zuk L,Marriage B,Simpson I,Mahachai V

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND AIM:To validate an early discharge policy in patients admitted with upper gastrointestinal bleeding (UGIB) due to ulcers. METHODS:Patients with gastroduodenal ulcer or erosive gastritis/duodenitis were included in a previous study aiming to develop a practice guideline for early discharge of patients wi...

journal_title：Journal of gastroenterology and hepatology

authors： Chaparro M,Barbero A,Martín L,Esteban C,Espinosa L,de la Morena F,Sánchez A,Martín I,Santander C,Moreno-Otero R,Gisbert JP

更新日期：2010-09-01 00:00:00

abstract：:Cancer stem cells (CSC) have been identified in a growing number of human malignancies. CSC are functionally defined by their ability to self-renew and recapitulate tumors in the ectopic setting, and a growing number of studies have shown that they display other functional characteristics, such as invasion and drug re...

journal_title：Journal of gastroenterology and hepatology

authors： Rasheed ZA,Matsui W

更新日期：2012-03-01 00:00:00

abstract：:Tuberculosis is known to involve the liver in different ways. The term hepatobiliary tuberculosis refers to the localized form of hepatic tuberculosis as a distinct clinical entity, with signs and symptoms related to the hepatobiliary tract. Its clinical features and the different diagnostic aids used in its diagnosis...

journal_title：Journal of gastroenterology and hepatology

authors： Alvarez SZ

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND AND AIM:Opioid-induced constipation (OIC) is a frequent adverse event (AE) that impairs patients' quality of life (QOL). Peripherally acting μ-opioid receptor antagonists (PAMORAs) have been recognized as a treatment option for OIC, but the effect consistent across the studies has not been evaluated. METHOD...

journal_title：Journal of gastroenterology and hepatology

authors： Nishie K,Yamamoto S,Yamaga T,Horigome N,Hanaoka M

更新日期：2019-05-01 00:00:00

abstract：:Recent research has led to an improved understanding of the aetiology of Budd-Chiari syndrome in some patients. Fresh approaches and technical developments within methods of radiological intervention have added more effective options to its treatment. In this editorial we aim to summarize our understanding of the role...

journal_title：Journal of gastroenterology and hepatology

authors： Mahmoud A,Elias E

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND AND AIM:Preoperative chemoradiotherapy (CRT) followed by esophagectomy is a well-known treatment modality for patients with locally advanced esophageal cancer (EC). This study developed an algorithm to predict pathological complete response (CR) in these patients using post-CRT endoscopic category with biops...

journal_title：Journal of gastroenterology and hepatology

authors： Cho CJ,Kang HJ,Park SJ,Kim GH,Park SH,Eo SH,Kim MJ,Kim YH,Park SR,Kim JH,Ahn JY,Kim DH,Choi KD,Song HJ,Jung HY,Park YS,Lee GH

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate and compare laparoscopic splenectomy and partial splenic embolization as supportive intervention for cirrhotic patients with hypersplenism to overcome peripheral cytopenia before the initiation of and during interferon therapy or anticancer therapy for hepatocellular carcinoma. METHODS:...

journal_title：Journal of gastroenterology and hepatology

authors： Tomikawa M,Akahoshi T,Sugimachi K,Ikeda Y,Yoshida K,Tanabe Y,Kawanaka H,Takenaka K,Hashizume M,Maehara Y

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND AIM:Radiation-induced colitis is a common clinical problem associated with radiotherapy and accidental exposure to ionizing radiation. Goblet cells play a pivotal role in the intestinal barrier against pathogenic bacteria. Rebamipide, an anti-gastric ulcer drug, has the effects to promote goblet cell pro...

journal_title：Journal of gastroenterology and hepatology

authors： Jang H,Park S,Lee J,Myung JK,Jang WS,Lee SJ,Myung H,Lee C,Kim H,Lee SS,Jin YW,Shim S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND AIM:The most effective schedule of proton pump inhibitor (PPI) administration and the optimal timing of endoscopy in acute peptic ulcer bleeding remain uncertain. The aim of this study was to determine the most efficient PPI regimen and optimal timing of endoscopy. METHODS:  Consecutive patients with su...

journal_title：Journal of gastroenterology and hepatology

authors： Liu N,Liu L,Zhang H,Gyawali PC,Zhang D,Yao L,Yang Y,Wu K,Ding J,Fan D

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND AIM:Owing to persistent controversy regarding the use of routine antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy and the availability of several new randomized controlled trials (RCTs), we conducted an up-to-date meta-analysis to provide the best current evidence. The ...

journal_title：Journal of gastroenterology and hepatology

authors： Liang B,Dai M,Zou Z

更新日期：2016-05-01 00:00:00

abstract：:Infiltrating leucocytes are activated to generate reactive oxygen species or to produce several molecules in inflamed colonic mucosa. To clarify the phenotypical and functional properties of activating cells in colitic mucosa, 23 patients with ulcerative colitis and 13 controls were studied using a combined method for...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Sawa Y,Hara J,Adachi K,Nakamura S,Matsumoto T,Arakawa T,Kuroki T

更新日期：1997-12-01 00:00:00

abstract：:The in vitro binding of 125I-labelled human alpha-interferon to peripheral blood mononuclear cells from 13 patients with chronic hepatitis B during interferon therapy was assayed in order to identify changes in the number of interferon receptors during treatment. Nine patients were treated with human alpha-interferon ...

journal_title：Journal of gastroenterology and hepatology

authors： Nakajima S,Kuroki T,Kurai O,Kobayashi K,Yamamoto S

更新日期：1989-09-01 00:00:00

abstract：:A seroepidemiological study was performed to clarify the prevalence of hepatitis delta virus (HDV) infection among the general population in the Irabu islands, Okinawa, Japan. Of 2028 healthy people examined who had received their annual health check-up in 1994-95, 195 (9.6%) were positive for hepatitis B surface anti...

journal_title：Journal of gastroenterology and hepatology

authors： Sakugawa H,Nakasone H,Shokita H,Kawakami Y,Nakachi N,Adaniya H,Mizushima T,Nakayoshi T,Kinjo F,Saito A,Taira M,Takaesu H,Onga N

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Endoscopic submucosal dissection (ESD) is now commonly performed as a treatment for colorectal tumors. However, little is known about the relationship between submucosal fibrosis and the outcome of the colonic ESD procedure. The aims of this study were to investigate the relationship between the deg...

journal_title：Journal of gastroenterology and hepatology

authors： Lee SP,Kim JH,Sung IK,Lee SY,Park HS,Shim CS,Han HS

更新日期：2015-05-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking variation in HCC incidence rates between various countries, with a highest-to-lowest ratio of 112.5 for males and 54.7 for females. The high-risk populations are clustered in sub-Saharan Africa and eastern Asia. The male-to-fe...

journal_title：Journal of gastroenterology and hepatology

authors： Chen CJ,Yu MW,Liaw YF

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatic fibrosis is a worldwide healthy burden associated with significant morbidity and mortality. It is caused by a variety of chronic liver injuries. There is currently no effective treatment for liver fibrosis. In this report, we tested an imidazolium salt, 1,3-diisopropylimidazolium tetrafluorob...

journal_title：Journal of gastroenterology and hepatology

authors： Ding Z,Zhuo L

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:Based on our previous studies that Artemisia asiatica extracts exert either antioxidative or cytoprotective actions against non-steroidal anti-inflammatory drugs or Helicobacter pylori-induced gastric mucosal injury, or imposes qualified ulcer healing in an acetic acid-induced gastric ulcer model, we...

journal_title：Journal of gastroenterology and hepatology

authors： Park SW,Oh TY,Kim YS,Sim H,Park SJ,Jang EJ,Park JS,Baik HW,Hahm KB

更新日期：2008-06-01 00:00:00

abstract：:Acute cholangitis is associated with significant morbidity and mortality. Endoscopic drainage procedures have been shown to be a safe and effective mode of treatment in acute cholangitis. As there is paucity of large series on endoscopic management of acute cholangitis, a study was performed to evaluate safety and eff...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma BC,Agarwal DK,Baijal SS,Saraswat VA,Choudhuri G,Naik SR

更新日期：1997-12-01 00:00:00

abstract：AIM:To investigate the morphological changes of intratumoral microvessels after administration of thalidomide in occult hepatic metastases. METHODS:Twenty mice with hepatic metastases created by injection of colon-26 tumor cells into the spleen were enrolled. Ten mice were treated with thalidomide (200 mg/kg) by intra...

journal_title：Journal of gastroenterology and hepatology

authors： Liu Y,Li H,Matsui O

更新日期：2009-06-01 00:00:00

abstract：:Continuing advances in molecular biology have provided tools for a promising approach to the treatment of cancer. Among the various strategies of gene therapy for cancer, many are aimed at killing tumour cells indirectly by the induction or reinforcement of a host immune response by gene transduction of various cytoki...

journal_title：Journal of gastroenterology and hepatology

authors： Cao G,Kuriyama S,Du P,Sakamoto T,Yang W,Masui K,Qi Z

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Probucol is a lipid-lowering agent with anti-oxidant effects. Oxidative stress and inflammation are important in the pathophysiology of insulin resistance. We aimed to evaluate the effects of probucol on liver histological changes, serum and hepatic levels of adipokines in rats with high fat-induced...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang X,Li Z,Liu D,Xu X,Shen W,Mei Z

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND AIM:Functional gastrointestinal disorders are the most common disorders in gastroenterology and are currently considered as gut-brain interaction disorders with multiple related factors including motility disturbance. However, high-resolution manometry (HRM) had revealed a new disease concept known as mi...

journal_title：Journal of gastroenterology and hepatology

authors： Sato H,Takahashi K,Mizuno KI,Hashimoto S,Kawata Y,Mizusawa T,Tominaga K,Yokoyama J,Terai S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Gradual normalization of conventional liver function tests occurs in a majority of patients with extrahepatic biliary obstruction following adequate biliary drainage. Abnormal recovery pattern of liver function has been reported in up to 70% of these patients and there is scarcity of relevant information abo...

journal_title：Journal of gastroenterology and hepatology

authors： Negi SS,Chaudhary A

更新日期：2005-10-01 00:00:00