The history of the hypophysis: the pioneering studies of Edoardo Gemelli.

abstract：BACKGROUND:Distal middle cerebral artery (MCA) aneurysms frequently have nonsaccular morphology that necessitates trapping and bypass. Bypasses can be difficult because efferent arteries lie deep in the opercular cleft and may not be easily identifiable. OBJECTIVE:We introduce the "flash fluorescence" technique, which...

journal_title：Neurosurgery

authors： Rodríguez-Hernández A,Lawton MT

更新日期：2012-06-01 00:00:00

abstract：:Clinical problems are often complex. Problems of great complexity are usually associated with a commensurately greater degree of difficulty with respect to the decision making process. This is most certainly true regarding the management of cervical spondylosis. Usually, clinicians make clinically appropriate decision...

journal_title：Neurosurgery

authors： Shedid D,Benzel EC

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:The incidence of reoperation for ventriculoperitoneal shunts (VPS) in adults, although lower than in pediatric patients, is not insignificant. We hypothesize that adult VPS placed for hemorrhage-related hydrocephalus have a lower incidence of reoperation than those placed for other types of hydrocephalus. ME...

journal_title：Neurosurgery

authors： Hoh BL,Lang SS,Ortiz MV,Chi YY,Lewis SB,Pincus DW

更新日期：2008-07-01 00:00:00

abstract：:Intraoperative ultrasound can aid the biopsy of deep intracranial lesions. It is, perhaps, less clear whether ultrasound could be useful in functional neurosurgery, where the target is not abnormal in echogenicity. As an example, we chose to investigate in a dog model the periventricular gray target, which is frequent...

journal_title：Neurosurgery

authors： Brown FD,Rachlin JR,Rubin JM,Fessler RG,Smith LJ,Schaible KL

更新日期：1984-08-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Desmoplastic infantile gangliogliomas (DIGs) are extremely rare tumors that respond well to treatment. However, their biological behavior remains to be clarified. We describe two patients whose DIGs spontaneously regressed after surgery, without adjuvant therapy. CLINICAL PRESENTATION:A 9-mont...

journal_title：Neurosurgery

authors： Takeshima H,Kawahara Y,Hirano H,Obara S,Niiro M,Kuratsu J

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To evaluate surgical access to the craniocervical junction using 3 endoscopic approaches: endonasal, transoral, and transcervical. METHODS:Nine cadaveric specimens were used. Image guidance was used in 1 specimen for each approach; fluoroscopy was used in every case. The Vitrea imaging station (Vital Images ...

journal_title：Neurosurgery

authors： Baird CJ,Conway JE,Sciubba DM,Prevedello DM,Quiñones-Hinojosa A,Kassam AB

更新日期：2009-12-01 00:00:00

abstract：:A compound of methylcellulose-silicone expanding progressively over a 1-week period by moisture absorption was implanted in the midthoracic epidural space of 17 Sprague Dawley adult rats. When the animals became paraplegic 6.3 +/- 1.6 days later, they were randomized into three groups: untreated control (n = 5), high ...

journal_title：Neurosurgery

authors： Delattre JY,Arbit E,Rosenblum MK,Thaler HT,Lau N,Galicich JH,Posner JB

更新日期：1988-06-01 00:00:00

abstract：:To investigate the role of protein kinase C (PKC) in the growth of astrocytic brain tumors, human glioblastoma cell line U-87 was stably transfected with the antisense complementary deoxyribonucleic acid encoding PKC alpha. The effect of selectively down-regulating the alpha isoform on other PKC isoforms, as well as s...

journal_title：Neurosurgery

authors： Ahmad S,Mineta T,Martuza RL,Glazer RI

更新日期：1994-11-01 00:00:00

abstract：:This retrospective review of pediatric patients with pituitary tumors causing onset of symptoms by 17 years of age was done to define their pathological distribution, clinical presentation, treatment, and prognosis. Eighteen patients were evaluated and treated from 1979 to 1989. Five had Cushing's disease and 13 had p...

journal_title：Neurosurgery

authors： Haddad SF,VanGilder JC,Menezes AH

更新日期：1991-10-01 00:00:00

abstract：:HIPPOCRATIC WORKS LEND themselves still today to the modern physician for further analysis of his approach to the diagnosis and treatment of various pathological conditions. We present an attempt to systematize his methodology regarding the management of head trauma and present it in the format of a modern-era algorit...

journal_title：Neurosurgery

authors： Dimopoulos VG,Machinis TG,Fountas KN,Robinson JS

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:During the past decade, management of posterior circulation aneurysms has shifted away from microsurgery. Currently, microsurgical clipping is considered a primary, competitive alternative to endovascular coiling, or more commonly, a secondary alternative when endovascular therapy is unfavorable. We present a...

journal_title：Neurosurgery

authors： Sanai N,Tarapore P,Lee AC,Lawton MT

更新日期：2008-06-01 00:00:00

abstract：:Reliable Assessment of the probability that a head injury patient harbors a surgical intracranial lesion is critical to both triage and treatment. The authors analyzed data from 608 patients with severe head injuries (Glasgow Coma Scale score, < or = 8) in the Traumatic Coma Data Bank to assess the reliability of pupi...

journal_title：Neurosurgery

authors： Chesnut RM,Gautille T,Blunt BA,Klauber MR,Marshall LE

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Examining the costs of single- and multilevel anterior cervical discectomy and fusion (ACDF) is important for the identification of cost drivers and potentially reducing patient costs. A novel tool at our institution provides direct costs for the identification of potential drivers. OBJECTIVE:To assess peri...

journal_title：Neurosurgery

authors： Reese JC,Karsy M,Twitchell S,Bisson EF

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Maximizing extent of resection (EOR) improves outcomes in adults with World Health Organization (WHO) grade II low-grade gliomas (LGG). However, recent studies demonstrate that LGGs bearing a mutation in the isocitrate dehydrogenase 1 (IDH1) gene are a distinct molecular and clinical entity. It remains uncle...

journal_title：Neurosurgery

authors： Patel T,Bander ED,Venn RA,Powell T,Cederquist GY,Schaefer PM,Puchi LA,Akhmerov A,Ogilvie S,Reiner AS,Moussazadeh N,Tabar V

更新日期：2018-06-01 00:00:00

abstract：:A successfully managed case of posterior fossa subdural hematoma occurring in a hemophiliac is reported, and the rarity of this lesion is mentioned. The management of the hemophiliac who is a victim of craniocerebral trauma is discussed, with emphasis on the use of computerized tomographic scanning to obtain rapid dia...

journal_title：Neurosurgery

authors： Raggio JF,Fleischer AS,Corley CC

更新日期：1978-09-01 00:00:00

abstract：OBJECTIVE:In this study, the incidence, etiologies, and management with respect to clinical outcome of patients with iatrogenic aneurysmal rupture during attempted coil embolization of intracranial aneurysms are reviewed. METHODS:A retrospective analysis was conducted of 274 patients with intracranial aneurysms treate...

journal_title：Neurosurgery

authors： Levy E,Koebbe CJ,Horowitz MB,Jungreis CA,Pride GL,Dutton K,Kassam A,Purdy PD

更新日期：2001-10-01 00:00:00

abstract：:This investigation attempts to determine whether increased survival time seen when the F98 glioma model is treated with boron neutron capture therapy (BNCT) is a result of inhibition of tumor growth caused by radiation-induced alterations in endothelial cells and normal tissue components. This indirect effect of radia...

journal_title：Neurosurgery

authors： Goodman JH,McGregor JM,Clendenon NR,Gahbauer RA,Barth RF,Soloway AH,Fairchild RG

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVE:We hypothesized that structural details that have not been described previously would be revealed in cerebral cavernous malformations (CCM) through the use of high-field magnetic resonance and confocal microscopy. The structural details of CCMs excised from patients were sought by examination with high-field ...

journal_title：Neurosurgery

authors： Shenkar R,Venkatasubramanian PN,Zhao JC,Batjer HH,Wyrwicz AM,Awad IA

更新日期：2008-10-01 00:00:00

abstract：:In four patients, shunt obstruction was accompanied by severe resting tremor involving principally the head, the jaw, the tongue, and the right upper extremity. Shunt revision resulted in improvement in each patient. Five similar patients have been reported. Although rare, the occurrence of parkinsonian tremor in a pr...

journal_title：Neurosurgery

authors： Keane JR

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:To compare anatomically the surgical exposure provided by pterional (PT), orbitozygomatic (OZ), and minisupraorbital (SO) craniotomies. METHODS:Seven sides of six fixed cadaver heads injected with silicone were used. The mini-SO craniotomy followed by the PT and OZ approaches were performed sequentially. The...

journal_title：Neurosurgery

authors： Figueiredo EG,Deshmukh V,Nakaji P,Deshmukh P,Crusius MU,Crawford N,Spetzler RF,Preul MC

更新日期：2006-10-01 00:00:00

abstract：:The management of 15 cases of bilateral locked facets of the cervical spine is reviewed. The C-6, C-7 interspace was the most common interspace involved. There were 4 females and 11 males who were 16 to 63 years old (average, 26 years). Thirteen patients had a complete spinal cord lesion with loss of function below th...

journal_title：Neurosurgery

authors： Sonntag VK

更新日期：1981-02-01 00:00:00

abstract：:The authors report their experience with 25 patients (mean age, 44.3 +/- 12.1 years) with an intracerebral hematoma (ICH) from a ruptured aneurysm who were emergently operated on without angiography. Instead, preoperative high-resolution infusion computed tomography (CT) scans were used to identify the aneurysm causin...

journal_title：Neurosurgery

authors： Le Roux PD,Dailey AT,Newell DW,Grady MS,Winn HR

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Cerebral edema contributes to the high morbidity and mortality of fulminant hepatic failure (FHF). OBJECTIVE:We report the results of our early experience with insertion of intraparenchymal intracranial pressure (ICP) monitors in these highly coagulopathic patients. METHODS:Eleven consecutive patients with...

journal_title：Neurosurgery

authors： Le TV,Rumbak MJ,Liu SS,Alsina AE,van Loveren H,Agazzi S

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To conduct a pilot trial of mild intraoperative hypothermia during cerebral aneurysm surgery. METHODS:One hundred fourteen patients undergoing cerebral aneurysm clipping with (n = 52) (World Federation of Neurological Surgeons score < or =III) and without (n = 62) acute aneurysmal subarachnoid hemorrhage (SA...

journal_title：Neurosurgery

authors： Hindman BJ,Todd MM,Gelb AW,Loftus CM,Craen RA,Schubert A,Mahla ME,Torner JC

更新日期：1999-01-01 00:00:00

abstract：:There are many elements to the science that drives the clinical care of patients with brain metastases. Although part of an understanding that continues to evolve, a number of key historical misconceptions remain that commonly drive physicians' and researchers' attitudes and approaches. By understanding how these rela...

journal_title：Neurosurgery

authors： Kondziolka D,Kalkanis SN,Mehta MP,Ahluwalia M,Loeffler JS

更新日期：2014-07-01 00:00:00

abstract：:The purpose of Clinical Problem Solving manuscripts is to present management challenges in an attempt to give practicing neurosurgeons insight into how field leaders address these dilemmas. This illustration is accompanied by a brief review of the literature on the topic. We describe the case of a patient who presente...

journal_title：Neurosurgery

authors： Natarajan SK,Siddiqui AH,Hopkins LN,Boulis NM,Levy EI

更新日期：2010-10-01 00:00:00

abstract：:Twenty patients who underwent early aneurysm surgery--that is, surgery within 72 hours after rupture--underwent further follow-up examination including magnetic resonance imaging (MRI) of the brain and a comprehensive neuropsychological assessment. Significant statistical correlation between tissue loss as seen on a l...

journal_title：Neurosurgery

authors： Romner B,Sonesson B,Ljunggren B,Brandt L,Säveland H,Holtås S

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:To determine whether adult human dorsal root ganglion neurons can be isolated and maintained in long-term tissue culture, where they would extend processes. METHODS:Dorsal root ganglia were removed from adult human organ donors within 2 hours of clamping the aorta. They were then treated with enzymes for one...

journal_title：Neurosurgery

authors： Sosa IJ,Reyes O,Inserni J,Kuffler DP

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Lymphocytic hypophysitis is being recognized with increasing frequency, but the long-term course is not well known. Recurrence of lymphocytic hypophysitis after a long interval has never been reported. CLINICAL PRESENTATION:A 53-year-old woman presented with central diabetes insipidus. Magneti...

journal_title：Neurosurgery

authors： Nishioka H,Ito H,Fukushima C

更新日期：1997-09-01 00:00:00

abstract：:After toxicity studies in dogs, a preliminary feasibility trial of the continuous intracranial infusion of a muscarinic agonist was begun in four patients with biopsy-documented Alzheimer's disease. During the last 8 months, a totally implantable infusion system has been used to deliver bethanechol chloride into the c...

journal_title：Neurosurgery

authors： Harbaugh RE,Roberts DW,Coombs DW,Saunders RL,Reeder TM

更新日期：1984-10-01 00:00:00