Isolation and long-term survival of adult human sensory neurons in vitro.

abstract：OBJECTIVE:It is still debated to what extent intraoperative electrophysiological techniques contribute to the outcome of subthalamic nucleus (STN) deep brain stimulation (DBS). Intraoperative electrophysiological recordings for identification of the STN can be made with one electrode or with multiple, simultaneously im...

journal_title：Neurosurgery

authors： Temel Y,Wilbrink P,Duits A,Boon P,Tromp S,Ackermans L,van Kranen-Mastenbroek V,Weber W,Visser-Vandewalle V

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:Experimental brain tumor gene therapy with the herpes simplex virus thymidine kinase (HSV-tk) gene has demonstrated that not only HSV-tk transduced but surrounding non-HSV-tk transduced cells are killed when given ganciclovir. This so-called bystander effect has recently been shown to be dependent on connexin...

journal_title：Neurosurgery

authors： Estin D,Li M,Spray D,Wu JK

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:We report the design and initial characterization of the dosimetry and radiobiology of a novel device for interstitial stereotactic radiosurgery. INSTRUMENTATION:The device is lightweight, handheld, and battery-powered, and it emits x-ray radiation from the tip of a probe 3 mm in diameter by 10 cm in length....

journal_title：Neurosurgery

authors： Hakim R,Zervas NT,Hakim F,Butler WE,Beatty J,Yanch JC,Biggs PJ,Gall KP,Sliski AP

更新日期：1997-03-01 00:00:00

abstract：:Holographic technology has recently been modified in such a manner that it may now provide clinical use. It allows the visualization of complex structures in three dimensions and permits clinician interaction with the image, which, in turn, provides significant additional geometric and anatomic information. To objecti...

journal_title：Neurosurgery

authors： Benzel EC,Rupp FW,McCormack BM,Baldwin NG,Anson JA,Adams MS

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:To improve intraoperative observation of unexposed anatomic features and to verify surgical correction, a mobile computed tomographic (CT) scanner has been introduced into the operating room. To date, intraoperative CT scanning has been used predominantly for intracranial procedures. We report on the expanded...

journal_title：Neurosurgery

authors： Hum B,Feigenbaum F,Cleary K,Henderson FC

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Carotid plaque characteristics influence future risk of stroke considerably. However, the severity of stenosis does not accurately reflect plaque burden in patients with expansive arterial remodeling. OBJECTIVE:To determine the therapeutic outcome of symptomatic carotid low-grade stenosis with vulnerable pl...

journal_title：Neurosurgery

authors： Yoshida K,Sadamasa N,Narumi O,Chin M,Yamagata S,Miyamoto S

更新日期：2012-05-01 00:00:00

abstract：:Nocardia asteroides is an uncommon human pathogen typically encountered in immunocompromised patients. Primary central nervous system (CNS) nocardiosis is rare and usually manifests as cerebritis or abscesses. The case of a young woman who presented with CNS Nocardia abscesses complicated by an infective middle cerebr...

journal_title：Neurosurgery

authors： Hadley MN,Spetzler RF,Martin NA,Johnson PC

更新日期：1988-05-01 00:00:00

abstract：:Therapy for thrombo-occlusive disease of the cerebral venous sinuses remains controversial. Although several thrombolytic agents, such as urokinase and anticoagulants, are recommended for treatment, major significant risks include cerebral hemorrhage, especially in patients with venous infarction. Tissue plasminogen a...

journal_title：Neurosurgery

authors： Alexander LF,Yamamoto Y,Ayoubi S,al-Mefty O,Smith RR

更新日期：1990-04-01 00:00:00

abstract：:A case involving giant and multiple aneurysms of the distal posterior inferior cerebellar artery (PICA) is presented. Of the 130 reported cases of peripheral aneurysms of the PICA, 6 have been described as giant aneurysms and 5 have involved multiple aneurysms located on a single PICA. The occurrence of multiple aneur...

journal_title：Neurosurgery

authors： Dernbach PD,Sila CA,Little JR

更新日期：1988-02-01 00:00:00

abstract：:The simple pathoanatomic concept that a narrowed spinal canal causes compression of the enclosed cord, leading to local tissue ischemia, injury, and neurological impairment, fails to explain the entire spectrum of clinical findings observed in cervical spondylotic myelopathy. A growing body of evidence indicates that ...

journal_title：Neurosurgery

authors： Henderson FC,Geddes JF,Vaccaro AR,Woodard E,Berry KJ,Benzel EC

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Motor cortex stimulation (MCS) is routinely used for the treatment of chronic neuropathic pain but its effect on quality of life remains uncertain. OBEJCTIVE:To systematically review the published literature on MCS and quality of life and report the effects of this therapy in a series of patients prospectiv...

journal_title：Neurosurgery

authors： Parravano DC,Ciampi DA,Fonoff ET,Monaco B,Navarro J,Yeng LT,Teixeira MJ,Hamani C

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To introduce a method for preoperative targeting of a proper recipient artery in superficial temporal artery-to-middle cerebral artery anastomosis. METHODS:Six operations for superficial temporal artery-to-middle cerebral artery anastomosis in four patients with moyamoya disease or moyamoya-like disease and ...

journal_title：Neurosurgery

authors： Kikuta K,Takagi Y,Fushimi Y,Ishizu K,Okada T,Hanakawa T,Miki Y,Fukuyama H,Nozaki K,Hashimoto N

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that subthalamic nucleus (STN) deep brain stimulation (DBS) improves tremor in Parkinson disease (PD). However, the patients included in those studies were unselected for tremor severity. OBJECTIVE:We specifically assessed the effect of STN DBS on tremor in selected PD patients w...

journal_title：Neurosurgery

authors： Kim HJ,Jeon BS,Paek SH,Lee JY,Kim HJ,Kim CK,Kim DG

更新日期：2010-09-01 00:00:00

abstract：:Intracranial electrical recordings and stimulation of neurosurgical patients have been central to the advancement of human neuroscience. The use of these methods has rapidly expanded over the last decade due to theoretical and technical advances, as well as the growing number of neurosurgical patients undergoing funct...

journal_title：Neurosurgery

authors： Chiong W,Leonard MK,Chang EF

更新日期：2018-07-01 00:00:00

abstract：:We present a case of neurocutaneous melanosis in a 1-year-old child who presented with progressive quadriparesis created by an infiltrating extra-axial neoplastic melanin-producing tumor at the foramen magnum. This extensive intra-arachnoid mass filled the basal cisterns of the brain and surrounded the upper cervical ...

journal_title：Neurosurgery

authors： Poe LB,Roitberg D,Galyon DD

更新日期：1994-10-01 00:00:00

abstract：:To evaluate the risk of tonsillar herniation, the caudal pole of the cerebellar tonsil in posterior fossa mass lesions and anomalies was investigated with magnetic resonance imaging. The cerebellar tonsil was clearly demonstrated in relation to the surrounding structures on T1-weighted images in the paramedian or midl...

journal_title：Neurosurgery

authors： Ishikawa M,Kikuchi H,Fujisawa I,Yonekawa Y

更新日期：1988-01-01 00:00:00

abstract：:The neurosurgical tradition at Jefferson Medical College began in the 19th century with Samuel Gross. In his textbook entitled A System of Surgery, Gross revealed his knowledge of the disorders of the nervous system at a time when innovations were practically inexistent. Gross' work paved the way for William Williams ...

journal_title：Neurosurgery

authors： Chalouhi N,Osterholm J,Jabbour P,Dumont AS,Gonzalez LF,Harrop J,Sharan A,Rosenwasser R,Tjoumakaris S

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:The anterior lumbar interbody fusion (ALIF) procedure has become an accepted fusion technique for treating patients with degenerative disorders of the lumbar spine. Many consider laparoscopic ALIF to be the least invasive approach. A modification of the open laparotomy--the "mini-open" approach--is an attract...

journal_title：Neurosurgery

authors： Kaiser MG,Haid RW Jr,Subach BR,Miller JS,Smith CD,Rodts GE Jr

更新日期：2002-07-01 00:00:00

abstract：:This investigation tested the hypothesis that the degree of impairment to memory function caused by an anterior temporal lobectomy (ATL) is inversely related to the pathological status of the resected hippocampus. Specifically, the greatest risk to postoperative memory function should be to patients with no or minimal...

journal_title：Neurosurgery

authors： Hermann BP,Wyler AR,Somes G,Berry AD 3rd,Dohan FC Jr

更新日期：1992-10-01 00:00:00

abstract：:A 60-year-old woman presented with a history of headache and rapidly progressive complete bilateral ophthalmoplegia. Her endocrine function was normal. Radiographic studies revealed signs of diffuse destruction of the sella turcica by a tumor without suprasellar extension. Biopsies of the lesion within the sphenoid si...

journal_title：Neurosurgery

authors： Nudleman KL,Choi B,Kusske JA

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Neurosurgical emergencies are an important cause of disability and mortality. OBJECTIVE:To examine the nationwide burden of neurological conditions requiring emergency neurosurgery. METHODS:The Nationwide Inpatient Sample database (2002-2011) was queried to identify adult patients with a primary discharge ...

journal_title：Neurosurgery

authors： De la Garza Ramos R,Goodwin CR,Nakhla J,Nasser R,Yassari R,Flamm ES,Bydon A,Colby G,Sciubba DM

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Although real-time localization of gliomas has improved with intraoperative image guidance systems, these tools are limited by brain shift, surgical cavity deformation, and expense. OBJECTIVE:To propose a novel method to perform near-infrared (NIR) imaging during glioma resections based on preclinical and c...

journal_title：Neurosurgery

authors： Lee JY,Thawani JP,Pierce J,Zeh R,Martinez-Lage M,Chanin M,Venegas O,Nims S,Learned K,Keating J,Singhal S

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND IMPORTANCE:Of the 170 cases of teratomas in the spinal canal reported in the English literature, only 13 were spinal epidural teratomas (SETs). We present a case of SET, review the characteristics of SETs in comparison with spinal intradural teratomas (SITs), and investigate the pathogenesis of spinal te...

journal_title：Neurosurgery

authors： Park SC,Kim KJ,Wang KC,Choe G,Kim HJ

更新日期：2010-12-01 00:00:00

abstract：:We previously reported that high dose naloxone (10 mg/kg) failed to promote recovery of motor function after a static load injury of the spinal cord in rats. In the present experiments, using the more traditional dynamic weight drop model, we tested megadose naloxone administered by the intraperitoneal route in 23 rat...

journal_title：Neurosurgery

authors： Black P,Markowitz RS,Keller S,Wachs K,Gillespie J,Finkelstein SD

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVE:A standard top-loading lumbar pedicle screw-rod system is compared with a pedicle screw-plate system with smaller-diameter screws, more medial entry, and lower profile to assess the relative stability, strength, and resistance to fatigue of the 2 systems. METHODS:Seven human cadaveric specimens were studied ...

journal_title：Neurosurgery

authors： Crawford NR,Doğan S,Yüksel KZ,Villasana-Ramos O,Soto-Barraza JC,Sawa AG,Porter RW,Marciano FF,Theodore N

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Lumbar discectomy is the most commonly performed spine procedure. Academic spine centers with potentially differing caseloads and experience may have different outcomes. OBJECTIVE:To determine whether the choice of center in which surgery is performed affects lumbar discectomy outcomes. METHODS:Spine Patie...

journal_title：Neurosurgery

authors： Desai A,Bekelis K,Ball PA,Lurie J,Mirza SK,Tosteson TD,Zhao W,Weinstein JN

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To study the biomechanical behavior of lumbar interbody instrumentation techniques using titanium cages as either transforaminal lumbar interbody fusion (TLIF) or anterior lumbar interbody fusion (ALIF), with and without posterior pedicle fixation. METHODS:Six fresh-frozen lumbar spines (L1-L5) were loaded w...

journal_title：Neurosurgery

authors： Niemeyer TK,Koriller M,Claes L,Kettler A,Werner K,Wilke HJ

更新日期：2006-12-01 00:00:00

abstract：:A retrospective study of 119 operative procedures for intracranial aneurysm was performed to compare the clinical result with microsurgical technique vs. that with standard instruments and without magnification; the operative technique was the major variable. The study demonstrated more normal patients, less intraoper...

journal_title：Neurosurgery

authors： Leibrock LG,Epstein MH,Long D

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:The energy index (EI) is a measure of dose homogeneity within a target volume calculated by the integral dose divided by the product of prescription dose and tumor volume. OBJECTIVE:To assess whether a higher EI is associated with greater local control for brain metastases (BMs) treated by Gamma Knife radio...

journal_title：Neurosurgery

authors： Jani A,Rozenblat T,Yaeh AM,Nanda T,Saad S,Qureshi YH,Feng W,Sisti MB,Bruce JN,McKhann GM 2nd,Lesser J,Lassman AB,Isaacson SR,Wang TJ

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:A two-stage approach using orbitozygomatic (OZ) and retrosigmoid (RS) craniotomies is one option for the management of petroclival lesions with supratentorial extension. The goal of this study was to investigate the supratentorial and infratentorial exposures of the clivus obtained through this staged approac...

journal_title：Neurosurgery

authors： Little AS,Jittapiromsak P,Crawford NR,Deshmukh P,Preul MC,Spetzler RF,Bambakidis NC

更新日期：2008-05-01 00:00:00