Abstract:
BACKGROUND AND IMPORTANCE:Of the 170 cases of teratomas in the spinal canal reported in the English literature, only 13 were spinal epidural teratomas (SETs). We present a case of SET, review the characteristics of SETs in comparison with spinal intradural teratomas (SITs), and investigate the pathogenesis of spinal teratoma. CLINICAL PRESENTATION:A 17-month-old boy visited our clinic with paraparesis. A multicystic mass was noted in the left epidural space from T8 to T10 and the left paraspinal area. Complete resection of the tumor, including the paraspinal portion, was accomplished by laminoplastic laminotomy. The tumor was well encapsulated and filled with heterogeneous contents. The tumor was suspected to originate from the left T9 root. CONCLUSION:On histopathological examination, the tumor was found to be a mature teratoma. The clinical characteristics of SETs and SITs show similarities in age, male preponderance, location, associated anomalies, and pathology. SETs and SITs are probably 2 different types of a single disease entity. Pluripotent somatic cell from the Hensen's node and caudal cell mass is the probable origin of spinal teratoma. However, originating from misplaced primordial germ cell could not be excluded.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Park SC,Kim KJ,Wang KC,Choe G,Kim HJdoi
10.1227/NEU.0b013e3181f846casubject
Has Abstractpub_date
2010-12-01 00:00:00pages
E1818-25issue
6eissn
0148-396Xissn
1524-4040pii
00006123-201012000-00048journal_volume
67pub_type
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