Tissue distribution and antitumor activity of topotecan delivered by intracerebral clysis in a rat glioma model.

abstract：:Between July 1975 and July 1985, 20 patients with 24 congenital distal anterior cerebral artery (DACA) aneurysms were admitted to our institution and underwent microsurgical clipping of their aneurysms. This group composes 4% of the 588 aneurysms managed surgically during this period. The clinical presentations includ...

journal_title：Neurosurgery

authors： Wisoff JH,Flamm ES

更新日期：1987-05-01 00:00:00

abstract：:Intravenously enhanced computed tomography (CT) was used in patients in whom the differential diagnosis between recurrent herniated disc and postoperative scar was considered. Enhanced CT images demonstrated postoperative herniated discs more accurately than clinical criteria, myelography, or plain or postmetrizamide ...

journal_title：Neurosurgery

authors： Schell GR,Modesti LM,Cacayorin ED

更新日期：1987-02-01 00:00:00

abstract：OBJECTIVE:Vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) is a potent angiogenic growth factor implicated in the tumor angiogenesis/metastasis of a number of human cancers. Activation of receptors for VEGF/VPF is specifically mitogenic to endothelial cells and increases their permeability. ...

journal_title：Neurosurgery

authors： Provias J,Claffey K,delAguila L,Lau N,Feldkamp M,Guha A

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:The treatment of residual and/or recurrent pituitary tumors, initially operated on through transsphenoidal and/or transcranial approaches, required a new single approach that would make it possible to excise the tumor from the sella and from the neighboring regions. Surgical complications, such as pneumatocep...

journal_title：Neurosurgery

authors： Dolenc VV

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:Fifty percent of implanted cerebrospinal fluid (CSF) shunts fail within 2 years, primarily because of obstruction of the proximal catheter. Percutaneous techniques to reduce the morbidity of shunt revision are being developed. The authors describe the development of a device that uses ultrasonic cavitation to...

journal_title：Neurosurgery

authors： Ginsberg HJ,Drake JM,Peterson TM,Cobbold RS

更新日期：2006-10-01 00:00:00

abstract：:Immortalized in surgical history for the introduction of "antiseptic wax," Sir Victor Horsley played a pivotal role in shaping the face of standard neurosurgical practice. His contributions include the first laminectomy for spinal neoplasm, the first carotid ligation for cerebral aneurysm, the curved skin flap, the tr...

journal_title：Neurosurgery

authors： Tan TC,Black PM

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Arteriovenous malformations (AVMs) involving the cerebellum and brainstem are relatively rare lesions that most often present clinically as a result of a hemorrhagic episode. Although these AVMs were once thought to have a more aggressive clinical course in comparison with supratentorial AVMs, recent autopsy ...

journal_title：Neurosurgery

authors： Sinclair J,Kelly ME,Steinberg GK

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To describe the pathological features of three very similar and unusual primary central nervous system tumors that are not readily recognized as conventional ependymomas but which, by ultrastructural examination, have an ependymomatous character. METHODS:Three distinctive tumors were found in a review of our...

journal_title：Neurosurgery

authors： Kleinman GM,Zagzag D,Miller DC

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Neuronavigation has become an intrinsic part of preoperative surgical planning and surgical procedures. However, many surgeons have the impression that accuracy decreases during surgery. OBJECTIVE:To quantify the decrease of neuronavigation accuracy and identify possible origins, we performed a retrospectiv...

journal_title：Neurosurgery

authors： Stieglitz LH,Fichtner J,Andres R,Schucht P,Krähenbühl AK,Raabe A,Beck J

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To investigate the potential of novel magnetic resonance (MR) angiographic techniques for the assessment of cerebral arteriovenous malformations. METHODS:Forty patients who were about to undergo stereotactic radiosurgery were prospectively recruited. Three-dimensional, sliding-slab interleaved ky (SLINKY), t...

journal_title：Neurosurgery

authors： Warren DJ,Hoggard N,Walton L,Radatz MW,Kemeny AA,Forster DM,Wilkinson ID,Griffiths PD

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Accurate placement of a probe to the deep regions of the brain is an important part of neurosurgery. In the modern era, magnetic resonance image (MRI)-based target planning with frame-based stereotaxis is the most common technique. OBJECTIVE:To quantify the inaccuracy in MRI-guided frame-based stereotaxis a...

journal_title：Neurosurgery

authors： Thani NB,Bala A,Lind CR

更新日期：2012-03-01 00:00:00

abstract：:Chiari malformations without myelodysplasia are rarely diagnosed in the pediatric age group. With current neurodiagnostic techniques, however, they are being seen more frequently. Unfortunately, the prognosis is not clear because publications have included a number of different entities, used a variety of surgical app...

journal_title：Neurosurgery

authors： Dyste GN,Menezes AH

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Anterior clinoidal meningiomas (ACMs) are a subgroup of meningiomas accounting for less than 10% of supratentorial meningiomas. OBJECTIVE:To assess the reliability and safeness of the lateral supraorbital approach (LSO) to remove ACMs. METHODS:Between September 1997 and October 2009, a total of 73 ACM pati...

journal_title：Neurosurgery

authors： Romani R,Laakso A,Kangasniemi M,Lehecka M,Hernesniemi J

更新日期：2011-06-01 00:00:00

abstract：:An unusual case of intradiploic epidermoid tumor is reported. In this case, a soft mass located over the parietal bone was noted shortly after birth. The mass gradually enlarged. The tumor underwent malignant change after several excisions and repeated inflammations. The patient was successfully treated with extensive...

journal_title：Neurosurgery

authors： Yanai Y,Tsuji R,Ohmori S,Tatara N,Kubota S,Nagashima C

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:To provide an overview of iatrogenic sciatic nerve injuries at the buttock and thigh levels, and to analyze results of the treatment provided at Louisiana State University Health Sciences Center-New Orleans. METHODS:The data from 196 patients were reviewed retrospectively. All patients had iatrogenic sciatic...

journal_title：Neurosurgery

authors： Yeremeyeva E,Kline DG,Kim DH

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Stereotactic radiosurgery (SRS) is an effective option in the management of brain metastases, offering improved overall survival to whole-brain radiation therapy (WBRT). However, given the need for active surveillance and the possibility of repeated interventions for local/distant brain recurrences, the bala...

journal_title：Neurosurgery

authors： Warsi NM,Karmur BS,Brar K,Moraes FY,Tsang DS,Laperriere N,Kondziolka D,Mansouri A

更新日期：2020-09-01 00:00:00

abstract：:The rete mirabile, a vascular network assumed to give origin to the intracranial segments of the internal carotid arteries, was interpreted by Galen as the key station for the conversion of the "vital spirit" into the "animal spirit." According to this interpretation, the rete was determinant either in sustaining the ...

journal_title：Neurosurgery

authors： Viale G

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Median nerve neuropathy can be clinically devastating to a patient. It can be caused by compression of the median nerve anywhere along its course. We present the case of delayed median nerve neuropathy after the placement of a vascular graft in the arm. CLINICAL PRESENTATION:An arm shunt was p...

journal_title：Neurosurgery

authors： Goldstein LJ,Helfend LK,Kordestani RK

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Although coiling of intracranial aneurysms is thought to rely on obstruction of blood flow into the aneurysm and induction of intra-aneurysmal thrombosis, little data exist regarding the effect of coil deployment on hemodynamics. OBJECTIVE:To evaluate the effects of simulated coiling of a model aneurysm on ...

journal_title：Neurosurgery

authors： Schirmer CM,Malek AM

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:There are few objective measures of functional impairment to support clinical decision making in lumbar degenerative disc disease (DDD). OBJECTIVE:We present the validation (and reliability measures) of the Timed Up and Go (TUG) test. METHODS:In a prospective, 2-center study, 253 consecutive patients were ...

journal_title：Neurosurgery

authors： Gautschi OP,Smoll NR,Corniola MV,Joswig H,Chau I,Hildebrandt G,Schaller K,Stienen MN

更新日期：2016-08-01 00:00:00

abstract：:We studied the effects of combination treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and low dose rate radiation in the 9L rat brain tumor in vivo model and the 9L multicellular tumor spheroid model. F-344 rats bearing intracerebral 9L gliosarcomas were implanted with removable 125I sources. Minimal (perip...

journal_title：Neurosurgery

authors： Gutin PH,Bernstein M,Sano Y,Deen DF

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:Free-hand insertion of an external ventricular drain (EVD) is a common emergency neurosurgical procedure, mostly performed for critically ill patients. Although EVD complications have been studied thoroughly, the accuracy of EVD positioning has been audited only occasionally. METHODS:Post-EVD insertion compu...

journal_title：Neurosurgery

authors： Toma AK,Camp S,Watkins LD,Grieve J,Kitchen ND

更新日期：2009-12-01 00:00:00

abstract：:The spinal form of brucellosis is still a disabling disease in many countries outside North America and northern and central Europe. Fifteen consecutive cases of spinal brucellosis diagnosed and treated over a 20-year period were reviewed retrospectively. Six patients were farmers, while 10 patients had a history of i...

journal_title：Neurosurgery

authors： Tekkök IH,Berker M,Ozcan OE,Ozgen T,Akalin E

更新日期：1993-11-01 00:00:00

abstract：:An 8-year-old boy presented with acute proptosis of the right eye. Examination revealed 8 mm of exophthalmos, limitation of upward gaze, optic disc swelling, and normal visual acuity, but an inferonasal quadrantic visual field defect. Orbital ultrasound and computed tomographic scanning demonstrated a superotemporal t...

journal_title：Neurosurgery

authors： Sebag J,Chapman P,Truman J,Riemersma RR

更新日期：1985-01-01 00:00:00

abstract：:INNOVATION IS THE driving force behind progress in neurosurgery. Most significant innovations require commercialization to ensure appropriate development and ultimate distribution to patients. There are several key factors that determine whether a particular innovation is likely to be commercially successful. Relation...

journal_title：Neurosurgery

authors： Firlik AD,Lowry DW,Levy AJ,Hirsch RC

更新日期：2000-07-01 00:00:00

abstract：:Although surgeons in Austria, especially in Vienna, were counted among the leading specialists at the end of the 19th century, neurosurgery did not evolve as a distinct discipline before the turn of the century; achievements were episodic until Anton von Eiselsberg became an enthusiastic surgeon of the central nervous...

journal_title：Neurosurgery

authors： Pendl G

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Although favorable clinical outcomes have been reported for instrumented lumbar interbody fusion (LIF), adjacent segment degeneration (ASD) has been reported as a long-term complication after LIF. OBJECTIVE:To investigate ASD after instrumented LIF performed at a single level and only for the homogeneous di...

journal_title：Neurosurgery

authors： Bae JS,Lee SH,Kim JS,Jung B,Choi G

更新日期：2010-12-01 00:00:00

abstract：:The simple pathoanatomic concept that a narrowed spinal canal causes compression of the enclosed cord, leading to local tissue ischemia, injury, and neurological impairment, fails to explain the entire spectrum of clinical findings observed in cervical spondylotic myelopathy. A growing body of evidence indicates that ...

journal_title：Neurosurgery

authors： Henderson FC,Geddes JF,Vaccaro AR,Woodard E,Berry KJ,Benzel EC

更新日期：2005-05-01 00:00:00

abstract：:A case of intracerebellar hematoma in infancy is reported. Although the clinical course and computed tomographic appearances suggested a cerebellar tumor, intraoperative and microscopic investigations demonstrated a chronic expanding hematoma enlarging with repeated hemorrhages inside the capsule. The differential dia...

journal_title：Neurosurgery

authors： Aoki N,Mizuguchi K

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:Radical resection of facial nerve schwannomas classically implies a high risk of severe facial palsy. Owing to the rarity of facial palsy after gamma knife surgery (GKS) of vestibular schwannomas, functional evaluation after GKS seems rational in this specific group of patients. To our knowledge, no previous ...

journal_title：Neurosurgery

authors： Litre CF,Gourg GP,Tamura M,Mdarhri D,Touzani A,Roche PH,Régis J

更新日期：2007-05-01 00:00:00