History of the Department of Neurosurgery at Thomas Jefferson University Hospital.

abstract：:The spinal form of brucellosis is still a disabling disease in many countries outside North America and northern and central Europe. Fifteen consecutive cases of spinal brucellosis diagnosed and treated over a 20-year period were reviewed retrospectively. Six patients were farmers, while 10 patients had a history of i...

journal_title：Neurosurgery

authors： Tekkök IH,Berker M,Ozcan OE,Ozgen T,Akalin E

更新日期：1993-11-01 00:00:00

abstract：:It is well known that the Horsley-Clarke frame was developed and first used by Robert Henry Clarke and the pioneer neurosurgeon Victor Horsley in 1906 for making lesions in the central nervous system of animals. The Horsley-Clarke frame was extensively used throughout the next 4 decades for excitation and lesion produ...

journal_title：Neurosurgery

authors： Jensen RL,Stone JL,Hayne RA

更新日期：1996-03-01 00:00:00

abstract：:A total scalp replantation was performed after a complete traumatic avulsion of the scalp with skull fracture. Multiple arterial and venous anastomoses were required. Satisfactory healing occurred, and the patient has had a subsequent uneventful cranioplasty to fill a bony defect, with normal scalp healing. ...

journal_title：Neurosurgery

authors： Chater NL,Buncke H,Brownstein M

更新日期：1978-05-01 00:00:00

abstract：:171 patients with intramedullary spinal cord tumors were operated on, of which 25 patients (15%), mostly children, developed symptomatic hydrocephalus. Twenty patients (12%) had malignant tumors, with 13 of the 20 cases (63%) complicated by increased intracranial pressure and ventriculomegaly. Of the remaining 151 pat...

journal_title：Neurosurgery

authors： Rifkinson-Mann S,Wisoff JH,Epstein F

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:To describe the neuropsychological functioning of children treated with surgery only for localized brain tumors in Dana-Farber Cancer Institute Protocol 92-077. Subsequent reports will describe the neuropsychological functioning of children treated with surgery and stereotactic radiation therapy on Dana-Farbe...

journal_title：Neurosurgery

authors： Carpentieri SC,Waber DP,Pomeroy SL,Scott RM,Goumnerova LC,Kieran MW,Billett AL,Tarbell NJ

更新日期：2003-06-01 00:00:00

abstract：:Research into the embryological development of organs has been of relevant interest for contemporary medicine since the 19th century. In particular, some organs, such as the pituitary gland, or hypophysis, were deemed not to have a specific function. They were thus considered as rudimental organs, a mere residue of ev...

journal_title：Neurosurgery

authors： Riva M,Cosmacini G,Mortini P

更新日期：2011-06-01 00:00:00

abstract：:Eleven athymic nude rats had stereotactic intracerebral inoculation of cells from one of three established human glioma cell lines (A172, A1207, and A1235). The implants grew progressively in 9 of 11 instances, which led to spontaneous death of the host in 14 to 37 days. For comparison, two Sprague-Dawley normal albin...

journal_title：Neurosurgery

authors： Finkelstein SD,Black P,Nowak TP,Hand CM,Christensen S,Finch PW

更新日期：1994-01-01 00:00:00

abstract：:Recent advances in electronics and microprocessors have enabled the development of a compact portable cerebral blood flow (CBF) machine capable of being transported to the patient's bedside. We have used such a device, the Novo Cerebrograph 2a, during the past 7 months on a regular basis in the day to day management o...

journal_title：Neurosurgery

authors： Rosenstein J,Suzuki M,Symon L,Redmond S

更新日期：1984-10-01 00:00:00

abstract：:Fetal visualization in utero can be routinely accomplished using noninvasive ultrasound techniques that do not administer ionizing radiation. Image resolution with real time sonography is sufficient to demonstrate details of possible congenital central nervous system malformations before delivery. The case reported il...

journal_title：Neurosurgery

authors： Weinstein P,Weinstein L,Dotters D,Bedrick A,Anderson C

更新日期：1983-06-01 00:00:00

abstract：:Seventy-one patients with minor head injury were given extensive neuropsychological evaluations 3 months after injury. A significant percentage of the patients demonstrated cognitive impairment, which seemed essentially unrelated to the length of unconsciousness or of posttraumatic amnesia. Impaired patients evidenced...

journal_title：Neurosurgery

authors： Barth JT,Macciocchi SN,Giordani B,Rimel R,Jane JA,Boll TJ

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:The blood-brain barrier (BBB) is often perceived as a passive membrane. However, evidence has demonstrated that the BBB plays an active role in normal homeostasis and in certain disease processes. METHODS:Approximately 300 peer-reviewed publications that discussed normal or abnormal BBB function were reviewe...

journal_title：Neurosurgery

authors： Neuwelt EA

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Tumor-associated sacral insufficiency fractures (SIF) present a significant clinical challenge. As survival increases for many malignancies, sacral fractures associated with metastases, sacral or extended pelvic radiation, and paraneoplastic osteoporosis are increasingly common and yet remain difficult to tr...

journal_title：Neurosurgery

authors： Moussazadeh N,Laufer I,Werner T,Krol G,Boland P,Bilsky MH,Lis E

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this investigation was to determine whether clinical speech deficits after brain injury are associated with functional speech reorganization. METHODS:Across an 18-year interval, 11 patients with mild-to-moderate speech deficits underwent language mapping as part of their treatment for intracta...

journal_title：Neurosurgery

authors： Lucas TH 2nd,Drane DL,Dodrill CB,Ojemann GA

更新日期：2008-09-01 00:00:00

abstract：:We present two cases of false aneurysm after carotid endarterectomy with primary arteriotomy closure. In both cases, infection appeared to be the precipitating cause. Both lesions were repaired with a saphenous vein patch graft, but infection in one patient persisted, and recurrence of a false aneurysm required ligati...

journal_title：Neurosurgery

authors： Branch CL Jr,Davis CH Jr

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Silent corticotroph adenomas (SCAs) are clinically nonfunctioning pituitary adenomas (NFPAs) with positive staining for corticotropin (ACTH) by immunohistochemistry. Whether SCAs behave more aggressively than NFPAs without ACTH immunoreactivity (ACTH negative) remains controversial. OBJECTIVE:To compare cha...

journal_title：Neurosurgery

authors： Ioachimescu AG,Eiland L,Chhabra VS,Mastrogianakis GM,Schniederjan MJ,Brat D,Pileggi AV,Oyesiku NM

更新日期：2012-08-01 00:00:00

abstract：:This retrospective review of pediatric patients with pituitary tumors causing onset of symptoms by 17 years of age was done to define their pathological distribution, clinical presentation, treatment, and prognosis. Eighteen patients were evaluated and treated from 1979 to 1989. Five had Cushing's disease and 13 had p...

journal_title：Neurosurgery

authors： Haddad SF,VanGilder JC,Menezes AH

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Revascularization rates with stent retrievers after acute ischemic stroke are 69% to 86%, but favorable clinical outcomes occur in just 43% to 58% of cases. New distal emboli may negatively impact clinical outcomes. OBJECTIVE:To determine the prevalence and angiographic pattern of distal emboli associated w...

journal_title：Neurosurgery

authors： Mazur MD,Kilburg C,Park MS,Taussky P

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Approximately 20% of low-grade gliomas (LGG) display visible protoporphyrin fluorescence during surgery after 5-aminolevulinic acid (5-ALA) administration. OBJECTIVE:To determine if fluorescence represents a prognostic marker in LGG. METHODS:Seventy-four consecutive patients with LGG (World Health Organiza...

journal_title：Neurosurgery

authors： Jaber M,Ewelt C,Wölfer J,Brokinkel B,Thomas C,Hasselblatt M,Grauer O,Stummer W

更新日期：2019-06-01 00:00:00

abstract：:A benign recurrence of a cerebellar juvenile astrocytoma was found in a 52-year-old woman 36 years after the initial radical removal, which was performed when she was 16 years of age. To our knowledge, this is the third detailed case report of the late benign recurrence of cerebellar astrocytoma after total removal. T...

journal_title：Neurosurgery

authors： Pagni CA,Giordana MT,Canavero S

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVE:Frequently, the cervicothoracic junction can be reached through a simple anterior approach. In some cases, access to this region requires a much more aggressive surgical intervention, such as manubriotomy or sternotomy. Information regarding the need for such interventions is particularly useful to have preop...

journal_title：Neurosurgery

authors： Karikari IO,Powers CJ,Isaacs RE

更新日期：2009-12-01 00:00:00

abstract：:Unexplained intraoperative or postoperative hemorrhage occurs in certain cases in the surgery of large arteriovenous malformations (AVMs), which are defined as those with maximal diameter of the nidus larger than 5 cm. Immediate postoperative angiograms were evaluated with reference to whether such hemorrhage could be...

journal_title：Neurosurgery

authors： Takemae T,Kobayashi S,Sugita K

更新日期：1993-09-01 00:00:00

abstract：:Although anterior and posterior traumatic displacement of cervical vertebrae are commonly noted, and the devastating neurological deficits associated with these injuries have been amply defined, lateral displacement with fractures has been rarely recognized, and the clinical significance of this injury has been overlo...

journal_title：Neurosurgery

authors： Parent AD,Harkey HL,Touchstone DA,Smith EE,Smith RR

更新日期：1992-09-01 00:00:00

abstract：:Today, physicians in general and neurosurgeons in particular practice in an era of fundamental change in Medicine from a profession to an industry. This change has produced erosion in the very personal physician-patient relationship. "The Morning Visit" is a poem written by Oliver Wendell Holmes, Sr., M.D., a 19th cen...

journal_title：Neurosurgery

authors： Ciric IS

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Arteriovenous malformations (AVMs) involving the cerebellum and brainstem are relatively rare lesions that most often present clinically as a result of a hemorrhagic episode. Although these AVMs were once thought to have a more aggressive clinical course in comparison with supratentorial AVMs, recent autopsy ...

journal_title：Neurosurgery

authors： Sinclair J,Kelly ME,Steinberg GK

更新日期：2006-04-01 00:00:00

abstract：:The authors report a review of 1808 patients admitted for the treatment of craniocerebral injuries. Eighty-four (4.6%) developed the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Two types of SIADH (severe and mild) were defined on the basis of laboratory findings and clinical signs. SIADH occur...

journal_title：Neurosurgery

authors： Dóczi T,Tarjányi J,Huszka E,Kiss J

更新日期：1982-06-01 00:00:00

abstract：OBJECTIVE:Endovascular treatment of intracranial aneurysms is less invasive than surgical repair but poses a higher risk for aneurysm recurrence, which may necessitate retreatment, thus adding to the long-term risk. Cerebrovascular neurosurgeons from 8 institutions in the United States and Puerto Rico collaborated to a...

journal_title：Neurosurgery

authors： Ringer AJ,Rodriguez-Mercado R,Veznedaroglu E,Levy EI,Hanel RA,Mericle RA,Lopes DK,Lanzino G,Boulos AS

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Intraoperative electrocorticography (ECoG) has been utilized in patients with tumor-associated seizures; however, its effectiveness for seizure control remains controversial. OBJECTIVE:To evaluate clinical outcomes in pediatric patients undergoing lesionectomy with or without ECoG. METHODS:Patients undergo...

journal_title：Neurosurgery

authors： Robertson FC,Ullrich NJ,Manley PE,Al-Sayegh H,Ma C,Goumnerova LC

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Iron catalyzed generation of injurious free radicals has been implicated in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH). The present study assessed the effects of the iron chelator deferiprone on cerebral vasospasm in an in vivo rabbit model of SAH. METHODS:Twenty-four rabbits ...

journal_title：Neurosurgery

authors： Arthur AS,Fergus AH,Lanzino G,Mathys J,Kassell NF,Lee KS

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To determine whether adult human dorsal root ganglion neurons can be isolated and maintained in long-term tissue culture, where they would extend processes. METHODS:Dorsal root ganglia were removed from adult human organ donors within 2 hours of clamping the aorta. They were then treated with enzymes for one...

journal_title：Neurosurgery

authors： Sosa IJ,Reyes O,Inserni J,Kuffler DP

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Two patients with vertebrobasilar dolichoectasia sustained massive fatal subarachnoid hemorrhage from rupture of the basilar artery wall. Hemorrhage from this entity is not widely known to occur during its natural history and may be exacerbated by systemic anticoagulation. CLINICAL PRESENTATIO...

journal_title：Neurosurgery

authors： Rabb CH,Barnwell SL

更新日期：1998-02-01 00:00:00