Mechanisms of disease: the blood-brain barrier.

abstract：:Therapy for thrombo-occlusive disease of the cerebral venous sinuses remains controversial. Although several thrombolytic agents, such as urokinase and anticoagulants, are recommended for treatment, major significant risks include cerebral hemorrhage, especially in patients with venous infarction. Tissue plasminogen a...

journal_title：Neurosurgery

authors： Alexander LF,Yamamoto Y,Ayoubi S,al-Mefty O,Smith RR

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Extent of resection (EOR) is well established as correlating with overall survival in patients with glioblastoma (GBM). The impact of EOR on reported quality metrics such as patient safety indicators (PSIs) and hospital-acquired conditions (HACs) is unknown. OBJECTIVE:To perform a retrospective study to eva...

journal_title：Neurosurgery

authors： Laurent D,Freedman R,Cope L,Sacks P,Abbatematteo J,Kubilis P,Bova F,Rahman M

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:In order to weigh the risks of surgery against the presumed advantages, it is important to have specific knowledge about complication rates. OBJECTIVE:To study the surgical mortality and rate of reoperations for hematomas and infections after intracranial surgery for brain tumors in a large, contemporary, s...

journal_title：Neurosurgery

authors： Lassen B,Helseth E,Rønning P,Scheie D,Johannesen TB,Mæhlen J,Langmoen IA,Meling TR

更新日期：2011-05-01 00:00:00

abstract：:A set of standard techniques to monitor the motor and sensory function of the cauda equina is proposed for surgery in the lumbosacral spinal canal for the release of a tethered cord or the removal of a neoplasm. Continuous loudspeaker-controlled recording of electromyographic activity in four leg muscles of both sides...

journal_title：Neurosurgery

authors： Kothbauer K,Schmid UD,Seiler RW,Eisner W

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the reclosure-promoting capacity of a neural stem cell line (F3) and a human bone marrow stem cell line (B10) injected into the amniotic cavity of spinal open neural tube defects (ONTDs) of chick embryos of Hamburger and Hamilton stage 18 or 19. METHODS:Fifteen chick embryos that survived the pro...

journal_title：Neurosurgery

authors： Lee DH,Phi JH,Kim SK,Cho BK,Kim SU,Wang KC

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Many patients with symptomatic Chiari I malformations experience symptom recurrence after surgical decompression. Identification of predictors of outcome is needed to better select patients most likely to benefit from surgical intervention. We examined whether or not cerebrospinal fluid (CSF) flow dynamics as...

journal_title：Neurosurgery

authors： McGirt MJ,Nimjee SM,Fuchs HE,George TM

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of embolization for spinal dural arteriovenous fistulae (SDAVF). METHODS:We reviewed 49 cases of SDAVF treated by embolization. An acrylic material was used in all except two cases. Variable stiffness microcatheters were used in 38 cases. RESULTS:"Adequate" initial treatment was per...

journal_title：Neurosurgery

authors： Niimi Y,Berenstein A,Setton A,Neophytides A

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:Because more women with cerebrospinal fluid shunts are surviving to child-bearing age, neurosurgeons, obstetricians, and other health care professionals require information about the care of these patients, especially during pregnancy and delivery. The purpose of this study was to gather comprehensive data fr...

journal_title：Neurosurgery

authors： Bradley NK,Liakos AM,McAllister JP 2nd,Magram G,Kinsman S,Bradley MK

更新日期：1998-09-01 00:00:00

abstract：:Haemophilus influenzae meningitis in the presence of a cerebrospinal fluid shunt has been reported uncommonly. Staphylococcus aureus and Staphylococcus epidermidis, the most common etiological agents, are usually acquired by contiguous spread from an intraoperative or perioperative source. These infections usually occ...

journal_title：Neurosurgery

authors： Petrak RM,Pottage JC Jr,Harris AA,Levin S

更新日期：1986-01-01 00:00:00

abstract：:A successfully managed case of posterior fossa subdural hematoma occurring in a hemophiliac is reported, and the rarity of this lesion is mentioned. The management of the hemophiliac who is a victim of craniocerebral trauma is discussed, with emphasis on the use of computerized tomographic scanning to obtain rapid dia...

journal_title：Neurosurgery

authors： Raggio JF,Fleischer AS,Corley CC

更新日期：1978-09-01 00:00:00

abstract：:Cerebral arterial vasospasm continues to be a major secondary medical complication of aneurysmal subarachnoid hemorrhage. Despite hypervolemic hemodilution, arterial hypertension, and pharmacological therapy, morbidity and mortality due to vasospasm remain high. The authors discuss a patient with vasospasm who did not...

journal_title：Neurosurgery

authors： Luer MS,Dujovny M,Slavin KV,Hernandez-Avila G,Ausman JI

更新日期：1995-05-01 00:00:00

abstract：:The authors report a review of 1808 patients admitted for the treatment of craniocerebral injuries. Eighty-four (4.6%) developed the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Two types of SIADH (severe and mild) were defined on the basis of laboratory findings and clinical signs. SIADH occur...

journal_title：Neurosurgery

authors： Dóczi T,Tarjányi J,Huszka E,Kiss J

更新日期：1982-06-01 00:00:00

abstract：OBJECTIVE:Embolization before surgical resection of tumors has been demonstrated to reduce intraoperative blood loss, but the optimal time that should elapse between embolization and tumor resection has not been established. We evaluated whether immediate surgical resection (< or =24 h) after embolization or delayed su...

journal_title：Neurosurgery

authors： Chun JY,McDermott MW,Lamborn KR,Wilson CB,Higashida R,Berger MS

更新日期：2002-06-01 00:00:00

abstract：:The techniques for the treatment of intracranial arteriovenous fistulae include angiographic balloon occlusion of the fistula as well as direct surgical attack. Regardless of the method, the occurrence of severe hyperemia caused by a lack of autoregulation after obliteration of the fistula remains a significant concer...

journal_title：Neurosurgery

authors： Giller CA,Batjer HH,Purdy P,Walker B,Mathews D

更新日期：1994-10-01 00:00:00

abstract：:Using rabbit cerebral arteries in an in vitro chamber, we examined the cerebral arterial contraction initiated by clotting whole blood. By using methysergide maleate and a novel thromboxane synthetase inhibitor, 1-carboxyheptylimidazole (1-CHI), we studied the contributions of both serotonin and the prostaglandin meta...

journal_title：Neurosurgery

authors： Schumacher MA,Alksne JF

更新日期：1981-09-01 00:00:00

abstract：:Modern medical education in the Ottoman Empire began with the founding of the School of Medicine and Surgery in 1827. This was a military school established to provide military physicians for the army. The first neurosurgical interventions at this school were initiated by Cemil Pasha in 1889. This school has gradually...

journal_title：Neurosurgery

authors： Timurkaynak E,Izci Y,Acar F

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:We report the initial results of a pilot clinical trial exploring the safety and feasibility of the first real-time magnetic resonance-guided laser-induced thermal therapy of treatment-resistant focal metastatic intracranial tumors. METHODS:Patients with resistant metastatic intracranial tumors who had previ...

journal_title：Neurosurgery

authors： Carpentier A,McNichols RJ,Stafford RJ,Itzcovitz J,Guichard JP,Reizine D,Delaloge S,Vicaut E,Payen D,Gowda A,George B

更新日期：2008-07-01 00:00:00

abstract：:The extent of treatment for the victims of gunshot wounds to the brain remains quite controversial, particularly when these patients present with extensive neurological dysfunction. We propose guidelines regarding the degree and aggressiveness of therapy. The factors that seem to have a significant impact on the patie...

journal_title：Neurosurgery

authors： Nagib MG,Rockswold GL,Sherman RS,Lagaard MW

更新日期：1986-05-01 00:00:00

abstract：:Three-dimensional computed tomographic scanning is a valuable adjunct in the diagnosis and treatment of disease processes involving the spine. We present our experience with this noninvasive radiological diagnostic technique in 32 patients with vertebral column abnormalities ranging from craniovertebral junction disor...

journal_title：Neurosurgery

authors： Hadley MN,Sonntag VK,Amos MR,Hodak JA,Lopez LJ

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:We sought to evaluate whether taurine detection in short-echo (20 ms) proton magnetic resonance spectroscopy contributes to the noninvasive differential diagnosis between medulloblastoma and cerebellar astrocytoma in children and young adults. These two types of tumor have very different prognoses and may be ...

journal_title：Neurosurgery

authors： Moreno-Torres A,Martínez-Pérez I,Baquero M,Campistol J,Capdevila A,Arús C,Pujol J

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Several studies have explored the effect of overlapping surgery on patient outcomes, but impact of surgical overlap during wound closure has not been studied. OBJECTIVE:To examine the association of overlap during wound closure and suture time overlap (STO) with patient outcomes in a heterogeneous neurosurg...

journal_title：Neurosurgery

authors： Glauser G,Agarwal P,Ramayya AG,Chen HI,Lee JYK,Schuster JM,Osiemo B,Goodrich S,Smith LJ,McClintock SD,Malhotra NR

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Biochemical alterations associated with mechanical stress have been explored as an initiating step in the pathological progression of ligamentum flavum hypertrophy (LFH); however, this mechanism remains poorly understood. Recently, the inflammation induced after mechanical stress and the subsequent response ...

journal_title：Neurosurgery

authors： Hur JW,Kim BJ,Park JH,Kim JH,Park YK,Kwon TH,Moon HJ

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Surgery for degenerative cervical spine disease has escalated since the 1990s. Fusion has become the mainstay of surgery despite concerns regarding adjacent segment degeneration. The patient-specific trends in reoperations have not been studied previously. OBJECTIVE:To analyze the occurrence, risk factors, ...

journal_title：Neurosurgery

authors： Kotkansalo A,Leinonen V,Korajoki M,Korhonen K,Rinne J,Malmivaara A

更新日期：2020-12-28 00:00:00

abstract：:ALTHOUGH FUNCTIONAL SURGERY for movement disorders did not begin in Korea until after the introduction of the stereotactic apparatus in 1958, some surgeons had already begun operating on epileptic patients, psychiatric patients, and patients with pain disorders even before the Korean War broke out in 1950. The Korean ...

journal_title：Neurosurgery

authors： Hwang SN

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To study the hyperacute histological and immunohistochemical effects of stereotactic proton beam irradiation of the rat hippocampus. METHODS:Nine rats underwent proton beam radiosurgery of one hippocampus with nominal doses of cobalt-2, -12, and -60 Gray equivalents (n = 3 each). Control animals (n = 3) were...

journal_title：Neurosurgery

authors： Brisman JL,Cosgrove GR,Thornton AF,Beer T,Bradley-Moore M,Shay CT,Hedley-Whyte ET,Cole AJ

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Radiation-induced changes (RICs) are the most common complication of stereotactic radiosurgery (SRS) for brain arteriovenous malformations (AVMs), and they appear as perinidal T2-weighted hyperintensities on magnetic resonance imaging, with or without associated neurological symptoms. OBJECTIVE:To determine...

journal_title：Neurosurgery

authors： Ilyas A,Chen CJ,Ding D,Buell TJ,Raper DMS,Lee CC,Xu Z,Sheehan JP

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:We report our initial clinical experience with a new method for intraoperative blood flow assessment. The purposes of the study were to assess the use of indocyanine green (ICG) video angiography in neurovascular cases, to assess the handling and image quality, to compare the findings with postoperative angio...

journal_title：Neurosurgery

authors： Raabe A,Beck J,Gerlach R,Zimmermann M,Seifert V

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:The most common postoperative complication of the transsphenoidal approach is cerebrospinal fluid (CSF) rhinorrhea. If the dura is widely opened beyond the sellar floor and massive intraoperative CSF leakage is encountered, then the conventional packing method, in which the sella turcica is filled with pieces...

journal_title：Neurosurgery

authors： Kitano M,Taneda M

更新日期：2004-03-01 00:00:00

abstract：:This experiment was designed to study the effects of intravascular volume expansion with crystalloid and colloid agents on intracranial pressure (ICP) and computerized electroencephalographic (EEG) data in dogs with cerebral vasogenic edema. A liquid nitrogen cold lesion was produced in the right parietal lobes of 30 ...

journal_title：Neurosurgery

authors： Tranmer BI,Iacobacci RI,Kindt GW

更新日期：1989-08-01 00:00:00

abstract：:Microfascicular double ligation and interligature heat sealing has been clinically successful in relieving neuroma pain. In rats, we found that this technique had no effect on the abnormal activities (such as mechanosensitivity and spontaneous activity) of single myelinated axons from neuromas or on their conduction v...

journal_title：Neurosurgery

authors： Tamas LB,Howe JF

更新日期：1984-06-01 00:00:00