Regional cerebral oxygen saturation during intra-arterial papaverine therapy for vasospasm: case report.

Abstract:

:Cerebral arterial vasospasm continues to be a major secondary medical complication of aneurysmal subarachnoid hemorrhage. Despite hypervolemic hemodilution, arterial hypertension, and pharmacological therapy, morbidity and mortality due to vasospasm remain high. The authors discuss a patient with vasospasm who did not respond to traditional medical therapy and who underwent intra-arterial papaverine infusions while being monitored with transcranial cerebral oximetry. Oximetry during the procedure revealed significant improvements in brain regional saturation of oxygen, with the relief of vasospasm that correlated with clinical improvements in the patient's neurological status. Transcranial cerebral oximetry was used to monitor regional oxygen saturation throughout the angiographic and interventional procedures, providing continuous, real-time, clinically relevant information about the effects of vasospasm and its treatment.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Luer MS,Dujovny M,Slavin KV,Hernandez-Avila G,Ausman JI

doi

10.1227/00006123-199505000-00024

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

1033-6

issue

5

eissn

0148-396X

issn

1524-4040

journal_volume

36

pub_type

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