Abstract：
BACKGROUND:Neuroendocrine tumours of the gastroenteropancreatic system (GEP-NETs) are rare, in particular those of the gallbladder. Due to the limited therapeutic options, surgical resection is favoured. CASE REPORT AND METHODS:Described below is the case of a 69-year-old male with a lymphogenically metastasising, poorly differentiated neuroendocrine carcinoma of the gallbladder who presented with unspecific abdominal pain. RESULTS AND CLINICAL COURSE:Following complete surgical resection of the tumour and the lymph node metastases he developed a recurrence 6 weeks post-operatively. The recurrence was treated with chemotherapy. Re-staging after three courses, however, showed further tumour progression. Prior to the start of a second-line treatment the patient died 13 weeks after surgery. CONCLUSIONS:This case demonstrates the complexity of this rare disease with diagnosis in advanced tumour stage and poor prognosis.
journal_name
Zentralbl Chirjournal_title
Zentralblatt fur Chirurgieauthors
Benkel M,Brasch F,Neumann JD,Altendorf-Hofmann A,Sendt Wdoi
10.1055/s-0030-1262764subject
Has Abstractpub_date
2012-02-01 00:00:00pages
71-2issue
1eissn
0044-409Xissn
1438-9592journal_volume
137pub_type
杂志文章abstract：:The future development of endoscopic surgery depends on a medical and economical benefit. Medical advantages are demonstrated under professional conditions of practice in a retrospective study: endoscopical repair of the groin (TEP n = 44) vs. conventional Shouldice- (n = 17) and Lichtenstein (n = 19) method, laparosc...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：INTRODUCTION:The resection of pulmonary metastases can extend life of patients, even offering the possibility of cure. A risk analysis of the surgical procedure under the current practice of the thoracic surgery has been performed in this study. MATERIALS AND METHODS:Using a prolective method, data from 199 patients w...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2005-918183
更新日期：2005-12-01 00:00:00
abstract：:Stabilisation of pelvic ring fractures by means of external fixation has been found to provide certain advantages over internal fixation. Good results can be achieved, provided that optimum forms and techniques of assembly are used. The authors' indications are reported together with their assembly techniques and form...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Mean nerve root diameters of thoracal, lumbal and sacral roots have been determined and the corresponding cross section areas calculated. The myelinated axons of these roots have been counted and the axon densities calculated. The myelinated axons of 3 lower intercostal nerves have also been counted. One intercostal n...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:In the last 7 years were observed 945 patients with head injuries in our emergency care. First aid is aimed to stabilize respiration and cardiovascular system and to avoid secondary posttraumatic lesions. ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Peritonitis is one of the most frequent infectious complications in patients with liver cirrhosis and ascites. In more than 95 % it occurs as spontaneous bacterial peritonitis (SBP) as a result of bacterial translocation from intestinal bacteria and bacterial products into mesenteric lymph nodes and subsequent systemi...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0031-1283815
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:Sacral nerve stimulation (SNS) is an effective and less invasive treatment of faecal incontinence (FI). Patient selection has evolved from strict criteria to a more liberal approach, since temporary testing reliably predicts the efficacy of permanent stimulation in FI of various aetiologies. PATIENTS AND ME...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2008-1004737
更新日期：2008-04-01 00:00:00
abstract：:Hepatic resections represent a standard procedure for both benign and malignant liver diseases. Nevertheless, typical complications arise follow-ing hepatic surgery. Besides common problems, such as bile leakage or impaired wound healing, rare complications, like progressive liver failure or portal vein thrombosis are...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0030-1247331
更新日期：2010-04-01 00:00:00
abstract：AIM OF THE STUDY:The surgical technique of transoral diverticulostomy by a modified Endo-GIAtrade mark Stapler (Multifire Endo GIA, Tyco Healthcare) is described. Experiences of this procedure in 31 patients are analysed and compared with different endoscopic and conventional surgical therapies of Zenker's diverticula,...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2007-981312
更新日期：2007-10-01 00:00:00
abstract：:5 patients suffered from melanoblastoma or thyroid cancer were treated with irradiation and cytostatics. The results of spermiograms before, and after treatment show with regard to fertility a moderate prognosis. ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Within the last nine years 125 patients underwent surgery for carcinoma of the oesophagus. In our cases oesophagogastrostomy has proved to be the most successful operative technique. The disappointing results of the first years could be improved significantly by standardized perioperative therapeutic measures. Because...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The shortage of surgeons in the operative disciplines field has in recent years further increased. The training of a surgeon and the required lifestyle combined with the work-life balance of the surgeons are perceived as being less attractive, so that young doctors after finishing medical school rarely decide for surg...
journal_title：Zentralblatt fur Chirurgie
pub_type：
doi：10.1055/s-0029-1224764
更新日期：2010-02-01 00:00:00
abstract：:During a period of 29 years (1960-1989), 19 patients with benign (15 cases) or malignant (4 cases) phylloides tumours were seen at the Surgical Clinic of Fundeni Hospital. Fourteen patients were followed up for a period of 2 to 21 years (mean 9.3 years). Two patients with benign tumours developed malignant recurrences...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Psychooncology is an interdisciplinary field that focuses on the various somatic, social and psychological factors influencing the well-being of oncological patients. Although the importance of psychooncological support of cancer patients is well accepted, universal standards for psychooncological care have not been e...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2008-1004664
更新日期：2008-02-01 00:00:00
abstract：:The planning of locoregional tumor therapy (radical surgical resection, curative radiotherapy) is based on the knowledge of locoregional tumor spread, in particular lymph node metastasis. In general, lymphatic spread follows anatomic rules, skipping of nodes is observed maximally in 3%. According to tumor site, uni- o...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-2000-10046
更新日期：2000-01-01 00:00:00
abstract：:On the basis of 341 liver biopsies routinely taken during cholecystectomies using Menghini's technique the pathological changes of the liver in comparison to the degree of cholecystitis were studied. Because of the frequency of morphological changes detected in the liver tissue, the low risk of the procedure and the p...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:In a period of 10 years we carried out two prospective multicentric trials to evaluate the state of the art in treatment of appendicitis. One study was performed before introduction of laparoscopy. Important criteria like new diagnostic methods (sonography, laparoscopy), frequency of operation, perforation rate, frequ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:In a period of 21 years we observed 28 tumours of the small bowel (14 benign, 14 malignant), what comes up to 0.85% of all tumours of the GI-tract seen at our hospital. The low rate of incidence of malignomas of the small bowel is supposed to be in relation with the carcinogenic indifference of its contents. 60% of th...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Traffic accidents are among the most important causes of child death. It is sometimes quite difficult to diagnose blunt abdominal traumata due to traffic accidents. 35 blunt hepatic and splenic injuries treated in our clinic during the period of 1971 to 1976 have been evaluated and pertinent references reviewed. ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:We report on the early and late complications after hernia repair in this retrospective study. Over a period of five years, 920 adult men underwent Bassini-Kirschner repair for inguinal hernia as first operation. There occurred six hematomas (0.6%), 11 seromas (1.2%) and 10 wound infections (1.0%). There were no death...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Indication for thoracotomy is undisputed in cases of gaping wounds with massive haemorrhage. However, discrete stab and gunshot wounds may quite often conceal imminent pericardial tamponade. Three quarters of all penetrating thorax injuries are located in or close to the cardiac silhouette. When it comes to patients w...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Since hemostaseologic therapies have a great impact on the budget of public health insurance companies, the therapy of hemophilia, prophylaxis of thrombosis and thrombolysis should be evaluated in a socioeconomic way. The substitution therapy in hemophilia is consuming a great deal of health care resources. The patien...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:In Germany, more than one million people use benzodiazepines on a regular basis. The majority of them is older than 60 years and take low-dose benzodiazepines for sleep disorders. This does not necessarily induce tolerance, but may result in problems such as falling, seizures or delirium if benzodiazepines a...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0041-107198
更新日期：2016-02-01 00:00:00
abstract：:The study described in this paper helped to establish the present position in locally delimited treatment of children for thermic injuries. 25 hospitals or other medical institutions were involved in the inquiry programme, including 16 departments of paediatric surgery and nine departments of general surgery. Studies ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:By the mean of a prospective multicenter observational study (East German Gastric Cancer Study - EGGCS), 1 139 consecutive patients with gastric cancer were enrolled in 80 East German surgical departments from January 1 to December 31, 2002. Out of them, 1,031 (90.5%) underwent surgical intervention. The resection rat...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,多中心研究
doi：10.1055/s-2005-836491
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Survival time is an important parameter to investigate therapeutic measures. It plays a crucial role in study concepts, data analyses as well as publications. AIM:The aim of this study was to emphasise essential points, which need to be taken into account to (i) gain resilient results of survival time analy...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0034-1383077
更新日期：2016-08-01 00:00:00
abstract：:The surgical treatment of chronic pancreatitis is indicated only in the complicated disease. The aim is mainly the treatment of pain, of mechanical obstacles and to exclude suspicion of cancer. Between October 1972 and January 1993 713 patients with chronic pancreatitis were treated at the Surgical University Hospital...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:Chylothorax is a rare complication after thoracic trauma or surgery, especially oesophagectomy, which, if left untreated, can be potentially life-threatening. METHODS:This article provides an overview of the existing literature on the prevention and surgical therapy of chylothorax. RESULTS:The risk of chyl...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/a-0608-5082
更新日期：2018-06-01 00:00:00
abstract：:In newborns, acute appendicitis is a very rare condition associated with significant lethality. Due to mostly non-specific symptoms, it is difficult to find the correct diagnosis preoperatively. Interestingly, rectal bleeding as a clinical sign in neonatal appendicitis is very uncommon. Here, we report on a 4-day-old ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-0028-1098922
更新日期：2009-12-01 00:00:00
abstract：INTRODUCTION:An adequate approach to surgically induced sepsis needs an early and targeted antibiotic therapy in addition to focus sanitation. The PCR-based LightCycler Septifast test can detect 90 % of the sepsis-associated microoganisms (e. g., Gram-positive, Gram-negative bacteria, fungi) within only a few hours. P...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-0028-1098776
更新日期：2009-06-01 00:00:00
