Abstract:
:Acoustic radiation force Impulse (ARFI) technology correlates shear-wave velocity with fibrosis. It can differentiate between advanced fibrosis and normal tissue in chronic liver disease. However, specificity is impaired by cholestasis, inflammation or oedema in acute hepatitis. In patients with acute liver failure (ALF) necessitating liver transplantation ARFI has not been evaluated yet. We investigated 3 patients with ALF and compared their ARFI results to those of healthy controls (n = 33) and cases with liver cirrhosis (n = 21). In the 3 ALF patients shear-wave velocities were 3.0, 2.5, and 2.7 m/s, respectively. These results were significantly increased compared to those of healthy controls (median: 1.13 m/s; p < 0.001) and similar to those of cirrhotic individuals (median: 2.93 m/s). Two individuals underwent liver transplantation. Explants showed massive necrosis, but no signs of chronic liver disease. Patient 3 recovered spontaneously and showed decreasing ARFI results during follow-up. In conclusion, hepatic necrosis can mimic liver cirrhosis at ARFI evaluation in ALF patients and this impairs the specificity of ARFI.
journal_name
Z Gastroenteroljournal_title
Zeitschrift fur Gastroenterologieauthors
Karlas TF,Pfrepper C,Rosendahl J,Benckert C,Wittekind C,Jonas S,Moessner J,Tröltzsch M,Tillmann HL,Berg T,Keim V,Wiegand Jdoi
10.1055/s-0029-1245690subject
Has Abstractpub_date
2011-04-01 00:00:00pages
443-8issue
4eissn
0044-2771issn
1439-7803journal_volume
49pub_type
杂志文章abstract::Chronic hepatic porphyrias (CHP) are associated with different degrees of liver damage. They range from minimal histological changes to cirrhosis and primary liver carcinomas. Forty patients with early stages of porphyrias were compared to 85 patients with clinically manifest porphyrias, Porphyria cutanea tarda. This ...
journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
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journal_title:Zeitschrift fur Gastroenterologie
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journal_title:Zeitschrift fur Gastroenterologie
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journal_title:Zeitschrift fur Gastroenterologie
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更新日期:1982-03-01 00:00:00
abstract::We report the case of a 70-year-old man who presented with hematochezia, anaemia, and severe abdominal pain 6 days after polypectomy. Contrast-enhanced ultrasound and computed tomography revealed no signs of free intra-abdominal air but showed intra-abdominal and intra-luminal bleeding. The patient was referred to col...
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更新日期:1993-06-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
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更新日期:1992-06-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章,评审
doi:
更新日期:1982-07-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章,评审
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journal_title:Zeitschrift fur Gastroenterologie
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
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pub_type: 杂志文章
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章,实务指引
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章,评审
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1986-05-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 临床试验,杂志文章
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更新日期:2004-04-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
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更新日期:2002-04-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章,评审
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
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journal_title:Zeitschrift fur Gastroenterologie
pub_type: 杂志文章
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