Abstract：
UNLABELLED:In the last decades, medical care has been increasingly permeated by the concept of evidence-based-medicine, in which clinical research plays a crucial role in establishing diagnostic and treatment. Following the improvements in clinical research, we have a growing concern and understanding that some ethical issues must be respected when the subjects are human beings. Research with human subjects relies on the principles of autonomy, beneficence, no maleficence and justice. Ordinance 196/96 from the National Health Board adds to the Brazilian legislation such renowned bioethical principles. AIM:Discuss the main ethical aspects involved in research with human subjects. MATERIALS AND METHODS:Critical analysis of Ordinance 196/96 and related literature. CONCLUSION:Ordinance 196/96 rules research with human subjects; nevertheless, it requires more in-depth discussions regarding the informed consent, use of placebo, research with vulnerable populations and research in developing countries.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Takahashi MT,Ramos HF,Pinheiro-Neto CD,Miziara ID,Oliveira RAdoi
10.1590/s1808-86942011000200018subject
Has Abstractpub_date
2011-03-01 00:00:00pages
263-6issue
2eissn
1808-8694issn
1808-8686pii
S1808-8694(15)30818-1journal_volume
77pub_type
杂志文章,评审abstract：INTRODUCTION:Norms and patterns of nasal esthetics are essential for an adequate preoperative evaluation and surgical programming. The esthetic nasal patterns used are a blend of artistic beauty ideals and tracings in models and celebrities. Because they do not consider population measures, they vary according to the p...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2017.06.004
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:The medial maxillary sinus roof is a ridge formed by the superior margin of the maxillary sinus antrostomy. The posterior wall of the maxillary sinus is always included in operative fields. OBJECTIVE:To perform a radiologic study assessing the utility of the medial maxillary sinus roof and the posterior w...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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abstract：UNLABELLED:The present study aimed at reporting on the characteristics, prognostic factors and treatment outcomes of 18 cases of nasosinusal mucosa melanoma, and do a literature review on the subject. METHODS:between 1995 and 2005, 18 patients consecutively diagnosed with nasosinusal mucosa melanoma were managed in ou...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1590/s1808-86942011000100010
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abstract：INTRODUCTION:Squamous cell carcinoma is the most common neoplasm of the larynx, and its evolution depends on tumor staging. Vascular endothelial growth factor is a marker of angiogenesis, and its expression may be related to increased tumor aggressiveness, as evidenced by the presence of cervical lymphatic metastases. ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.08.016
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abstract：UNLABELLED:Hearing loss is more prevalent than other disorders found at birth. Efforts have been put up towards the early identification and treatment of hearing loss by means of neonatal hearing screening programs. AIM:prospective study with the goal of characterizing the process of implementing a Neonatal Auditory S...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30784-9
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abstract：INTRODUCTION:Newborn hearing screening (NHS) programs are implemented across the globe to detect early hearing impairment. In order to meet this objective, the quality of these programs should be monitored using internationally recognized indicators. OBJECTIVE:To evaluate a newborn hearing screening service (NHSS) usi...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.08.008
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abstract：INTRODUCTION:Mismatch negativity, an electrophysiological measure, evaluates the brain's capacity to discriminate sounds, regardless of attentional and behavioral capacity. Thus, this auditory event-related potential is promising in the study of the neurophysiological basis underlying auditory processing. OBJECTIVE:To...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.08.022
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abstract：UNLABELLED:Long latency auditory evoked potentials (LLAEP) alterations in individuals with tinnitus are suggestive of dysfunction in the central auditory pathways at a cortical level. AIM:To characterize the LLAEP in individuals with and without tinnitus exposed to occupational noise. METHOD:Cross-sectional contempor...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
abstract：UNLABELLED:Auditory evoked brainstem responses (ABR) is a non-invasive electrical potential registration which evaluates the auditory tract from the middle ear to the auditory cortex in the first 12 milliseconds (ms). The ABR is an important otoneurological evaluation. AIM:Confirm the test's usefulness, major incidenc...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2008-07-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2015-03-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/j.bjorl.2017.10.013
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-11-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.5935/1808-8694.20130128
更新日期：2013-11-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2012-10-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2020.06.012
更新日期：2020-08-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.5935/1808-8694.20120035
更新日期：2012-12-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2015.05.015
更新日期：2016-07-01 00:00:00
abstract：UNLABELLED:Cleft lip and palate (CLP) is a risk indicator to middle ear alterations, which may damage the development of auditory abilities such as attention that is essential to learn new skills, oral and written communication. Studies on attention process with CLP population are recent and poorly explored in the spec...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
abstract：AIM:To assess whether or not the parameters of fixed and randomized saccadic movements, of pendular tracking and of optokinetic nystagmus in the digital vectonystagmography may show abnormalities in patients with possible diagnosis of peripheral vestibular dysfunction. METHOD:60 patients with dizziness of peripheral v...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2006-05-01 00:00:00
