Fever of unknown origin from a left atrial myxoma: an immunologic basis and cytokine association.

Abstract:

:Myxoma is the most common primary tumor of the heart. The typical presentations include a triad of embolic phenomena, intracardiac flow obstruction, and constitutional symptoms. We report a case of cardiac myxoma presenting as prolonged fever. Leukocytosis with a left shift, anemia, and elevated C-reactive protein were noted. A large left atrial myxoma was found incidentally by chest computed tomography. The fever subsided after surgical removal of the myxoma. His elevated serum interleukin-4 (IL-4), IL-6, IL-12 p70, interferon-γ, and tumor necrosis factor-α returned to undetectable levels four days after surgery. Cardiac myxomas should be included in the differential diagnosis of prolonged fever, even though no typical symptoms could be found.

journal_name

South Med J

journal_title

Southern medical journal

authors

Lin JN,Lai CH,Lu LF,Lin HH

doi

10.1097/SMJ.0b013e3182142bbd

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

360-2

issue

5

eissn

0038-4348

issn

1541-8243

pii

00007611-201105000-00019

journal_volume

104

pub_type

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