Abstract:
:Melatonin, a hormone produced by the pineal gland, may be a promising treatment option for tinnitus. The primary functions of this hormone are believed to be the initiation and maintenance of sleep because its secretions coincide with circadian rhythms. Some investigators have noted that melatonin may alleviate subjective symptoms of tinnitus. Moreover, melatonin may have properties protective against ototoxic drugs such as amikacin, gentamicin, or cancer therapeutic agents that are dose dependent. In vitro, melatonin has demonstrated antioxidative properties and it has been postulated that these antioxidative properties contribute to the alleviation of tinnitus. Melatonin levels used to obtain these findings in vitro, however, are at supraphysiologic levels; therefore, it is more likely that the benefits from taking supplemental melatonin occur from minimal antioxidative properties, sleep enhancement, or other potential methods of action that are not yet understood. Melatonin offers minimal risk of toxicity with modest daily doses such as 1 to 3 mg, as well as a low cost and favorable adverse effect profile for older adults. In addition to potential benefits in the treatment of tinnitus, melatonin also may have beneficial neurogenerative properties. We recommend that melatonin be considered for use in patients with significant tinnitus.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Merrick L,Youssef D,Tanner M,Peiris ANdoi
10.14423/01.SMJ.0000450714.38550.d4subject
Has Abstractpub_date
2014-06-01 00:00:00pages
362-6issue
6eissn
0038-4348issn
1541-8243pii
SMJ13251journal_volume
107pub_type
杂志文章,评审abstract::With ever-increasing costs confronting health care facilities, much attention is being focused on various cost-containment projects. Although it is generally assumed that a radiology department quality control program will increase costs, institutional savings may also result. A comprehensive quality control program i...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198002000-00020
更新日期:1980-02-01 00:00:00
abstract::The Pelorus Stereotactic Surgical System is a relatively new, commercially available device that can be used to perform computed tomography (CT)-guided stereotactic brain biopsy. It has been promoted as being a relatively simple and inexpensive system that is more rapid, less cumbersome, and generally easier to use th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199307000-00008
更新日期:1993-07-01 00:00:00
abstract::Bile drainage through normal lymphatic pathways has been described, but bile drainage from the liver to the duodenum via lymphatic collaterals has not. We have described a patient with a common bile duct stricture and lymphatic drainage of bile into the duodenum. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198401000-00028
更新日期:1984-01-01 00:00:00
abstract::Treatment of the adult respiratory distress syndrome requires an understanding of the current concepts of the pathogenesis of this syndrome. The clinical features and pathophysiology are briefly discussed. Differential diagnosis requires the exclusion of pulmonary infection and left heart failure. Therapy is aimed at ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-197811000-00028
更新日期:1978-11-01 00:00:00
abstract::Perennial allergic rhinitis (PAR) can have a significant impact on a patient's quality of life. While allergen avoidance is the first line of management for PAR, complete avoidance is difficult. Therapeutic options available for PAR include intranasal corticosteroids (INS), H1-antihistamines, decongestants and local c...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3180485560
更新日期:2007-07-01 00:00:00
abstract::To our knowledge, this is the first known case of a patient with leptospirosis and very elevated CSF, which caused hydrocephalus. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181a0ae80
更新日期:2009-05-01 00:00:00
abstract::A retrospective study of 45 patients hospitalized with blastomycosis of bones or joints revealed 41 cases of osteomyelitis and 12 cases of septic arthritis. The majority were men (35 [78%] patients) and non-Aboriginal (32 [71%] patients). Median time from the onset of symptoms to hospitalization was shorter in women t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3180487a92
更新日期:2007-06-01 00:00:00
abstract::We recently managed a patient with diabetic ketoacidosis who had an exceptionally high arterial oxygen tension of 144 mm Hg while breathing room air. This was higher than the calculated alveolar oxygen tension and suggested the impossible situation of an uphill diffusion gradient. We were surprised to find this is a r...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00013
更新日期:1979-09-01 00:00:00
abstract:OBJECTIVES:The objective of this population-based study was to examine the relationship between race, socioeconomic characteristics (socioeconomic status, SES), physician density, and colon cancer incidence in Alabama. METHODS:Data for 5,788 colon cancer cases from 1996 to 1999 provided by the Alabama Statewide Cancer...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000184844.01148.10
更新日期:2005-11-01 00:00:00
abstract::Continued improvements in computer technology have led to significant enhancement of clinical teaching. We describe a "digital toolbox" consisting of personally accessible hardware and software products to assist in clinical teaching. The areas covered are computer-assisted diagnosis, digitization and display of clini...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199512000-00003
更新日期:1995-12-01 00:00:00
abstract::A 46-year-old woman had features of acute pulmonary edema soon after taking hydrochlorothiazide (HCTZ) for the first time. Although 31 cases of HCTZ-induced pulmonary edema have been reported in the world literature since it was first described in 1968, little is known about this clinical entity. Because its presence ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199911000-00013
更新日期:1999-11-01 00:00:00
abstract::Perinephric and prostatic abscesses may present with protean symptoms and often arise from ascending urinary tract infections. Both abscesses are often caused by uropathogens, and only on rare occasions is the etiology due to methacillin-resistant Staphylococcus aureus (MRSA). Perinephric and prostatic abscesses have ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31802fff6e
更新日期:2007-05-01 00:00:00
abstract::Coronary heart disease remains the major cause of mortality and morbidity in the United States and other western countries despite major advances in its treatment. During the last decades, many markers of coronary artery disease have been found which help predict future risk of cardiovascular events. High-sensitivity ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e31816c0195
更新日期:2008-05-01 00:00:00
abstract::Appropriate use of antibiotics is enhanced by the effective application of data on antimicrobial susceptibility. A number of methods are currently available for routine determination of susceptibilities, including agar dilution, broth dilution, agar diffusion, and several semiautomated methods. If susceptibility testi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00
abstract::Safety restraints have proven effective in the prevention of serious automobile injuries and deaths, but safety education has been ineffective in getting consumers to use restraints. We surveyed the personal and counseling practices of a group of pediatricians over a one-year period to determine whether prenatal and p...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198110000-00003
更新日期:1981-10-01 00:00:00
abstract:OBJECTIVES:Insurance status has the potential to play a significant role in an individual's health care by affecting the time of diagnosis and the treatment options used. Our study reviewed insurance status as a determinant of the time of a breast cancer diagnosis as well as the surgical treatment options offered. MET...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000281
更新日期:2015-05-01 00:00:00
abstract::We have described three patients with diabetes and renal insufficiency who had hyperkalemia during heparin therapy. These cases lend support to previous findings, and emphasize the clinical importance of this entity. We believe that heparin-induced hyperkalemia is a potentially life-threatening problem that is more co...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198711000-00029
更新日期:1987-11-01 00:00:00
abstract::We report four cases of group A streptococcal vulvovaginitis in prepubertal children. All cases were acute in onset. This illness presents with nonspecific signs and symptoms of labial inflammation. In a suburban community, streptococcal vulvovaginitis in prepubescent girls may be more common then genital infections d...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198204000-00017
更新日期:1982-04-01 00:00:00
abstract::Preventive screening measures for low back pain are limited. Despite considerable evidence that anatomic narrowing of the lumbar spinal canal is a risk factor for specific back problems, difficulty in measuring the canal without unacceptable radiation exposure, cost, or discomfort has limited the assessment of its cli...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198908000-00012
更新日期:1989-08-01 00:00:00
abstract::We describe a patient with pseudotumor cerebri for which a lumboperitoneal (LP) shunt was placed. After a pseudomeningocele was noted at the lumbar incision site, an LP shunt revision was done, at which time migration of the catheter into the thecal sac was noted. Three months later, radiologic studies revealed crania...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199606000-00019
更新日期:1996-06-01 00:00:00
abstract::Appendicovesical fistula is an uncommon condition usually occurring in boys and young men and associated with chronic urinary tract infection. Diagnosis is based on cystoscopic findings that may be confirmed by a retrograde study. Treatment by appendectomy is usually successful. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198004000-00037
更新日期:1980-04-01 00:00:00
abstract::We have described a patient with portal hypertension and retrocardiac paramediastinal density on upright PA chest x-ray film. Splenoportograms showed this density to be paraesophageal collateral veins. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198511000-00030
更新日期:1985-11-01 00:00:00
abstract:OBJECTIVES:Shear wave elastography (SWE) is an emerging technology that assesses hepatic fibrosis. The aim of our study was to determine the diagnostic accuracy of General Electric (GE) Healthcare's LOGIQ E9 SWE in patients with chronic hepatitis C virus using liver biopsy as the reference standard. METHODS:The liver ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000562
更新日期:2016-11-01 00:00:00
abstract::Optimal antimicrobial therapy for viridans streptococcal endocarditis remains controversial. Rifampin was bactericidal at less than 0.2 micrograms/ml for ten strains of viridans streptococci isolated from patients with endocarditis. Administration of rifampin to one endocarditis patient already receiving penicillin an...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198308000-00005
更新日期:1983-08-01 00:00:00
abstract::We have described an adenocarcinoma observed as a grossly discrete area within a cystadenofibroma of the ovary. Fewer than 35 cases of malignant cystadenofibroma have been reported. We find our observations lend support to the prevailing thought that these neoplasms most often originate from preexisting cystadenofibro...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198504000-00030
更新日期:1985-04-01 00:00:00
abstract::We have described a case of reversible acute renal failure caused by acute pyelonephritis. In this entity, the kidneys are swollen by an interstitial infiltrate and edema, and white cell tubular casts and microabscesses may be present. Fractional excretion of sodium is high, and nephrotic proteinuria may occur without...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198003000-00030
更新日期:1980-03-01 00:00:00
abstract:OBJECTIVES:People living with human immunodeficiency virus (HIV) have an increased risk of other infections, including viral hepatitis, which can complicate the treatment and progression of the disease. We sought to characterize Alabama cases of HIV co-infected with hepatitis C virus or hepatitis B virus. METHODS:Usin...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001104
更新日期:2020-06-01 00:00:00
abstract::A 63 year-old woman who had had mitral valve commissurotomy 12 years earlier was seen because of rheumatic mitral stenosis and left brachial paresis due to cerebral embolism. On clinical evaluation, a diastolic rumble was heard over the mitral area, and the echocardiogram revealed a mass attached to the mitral subvalv...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199910000-00017
更新日期:1999-10-01 00:00:00
abstract::Mesenteric lipodystrophy (ML) is a rare condition characterized by a nonspecific inflammatory process that involves the root of the mesentery in a lipoma-like lesion. Presenting features of ML include abdominal pain, weight loss, nausea, vomiting, diarrhea, and constipation. This case illustrates that ML should be inc...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199905000-00013
更新日期:1999-05-01 00:00:00
abstract::The patient we have described had lower extremity numbness, paresthesias, constipation, urinary retention, and sexual dysfunction. Laboratory evaluation confirmed a diagnosis of acute intermittent porphyria (AIP). Vitamin B6 and glucose therapy initiated resolution of symptoms. The sensory neuropathy described here is...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00