Abstract:
:The Pelorus Stereotactic Surgical System is a relatively new, commercially available device that can be used to perform computed tomography (CT)-guided stereotactic brain biopsy. It has been promoted as being a relatively simple and inexpensive system that is more rapid, less cumbersome, and generally easier to use than conventional stereotactic frames. In this paper, we describe the Pelorus System, and report on its diagnostic accuracy and associated morbidity, based on our experience with 49 consecutive patients in two institutions. Patients ranging from 7 months to 85 years of age had CT-guided stereotactic biopsy, primarily for diagnosis of lesions deep within the cerebral hemispheres. Two transfrontal biopsies of the lateral pons were also done. Satisfactory tissue for histologic diagnosis was obtained in 42 of 49 patients (86%). In this series, there were two deaths in the immediate postoperative period, unrelated to the use of the Pelorus System. One patient suffered a transient neurologic deficit, which resolved over a period of 3 days. Although the Pelorus System has some limitations, we found it easy to use, well-tolerated by patients, and useful for performing CT-guided stereotactic biopsy.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Engelhard HH,Nazar GB,Grieser GMdoi
10.1097/00007611-199307000-00008subject
Has Abstractpub_date
1993-07-01 00:00:00pages
760-6issue
7eissn
0038-4348issn
1541-8243journal_volume
86pub_type
杂志文章abstract:OBJECTIVE:Intraventricular hemorrhage (IVH) represents a clinicopathologic entity with a dismal prognosis. The associated mortality rate has been reported as high as 80%; the morbidity is also quite high. The use of various fibrinolytic agents (streptokinase, urokinase, and recombinant tissue-type plasminogen activator...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/01.smj.0000170732.24324.ea
更新日期:2005-08-01 00:00:00
abstract::Primary small cell undifferentiated carcinomas (SCUCs) are unusual tumors of the colon and rectum. Histologically, these lesions represent a spectrum of neuroendocrine differentiation, with oat cell carcinoma being the most primitive subtype and carcinoid tumors being the most differentiated. This observation is suppo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199609000-00016
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVES:The use of monitored anesthesia care (MAC) for colonoscopy sedation continues to increase. This study examined trends during a 9-year period in the use of MAC and explored which patient variables may have influenced these trends. METHODS:This was a retrospective review of all colonoscopies performed in our ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000338
更新日期:2015-09-01 00:00:00
abstract::High fever occurred in a 30-year-old woman five weeks after transsphenoidal hypophysectomy for a pituitary adenoma. Extensive investigation failed to reveal any evidence of infection, and the clinical findings suggested the fever to be a manifestation of steroid withdrawal. Either suboptimal dosage of corticosteroid r...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198903000-00027
更新日期:1989-03-01 00:00:00
abstract::In a retrospective review from 1987 to 1989, we identified seven alcoholics who had severe acute hepatocellular injury soon after using acetaminophen for therapeutic purposes and who had no suicidal intent. All had markedly elevated serum transaminase values (aspartate aminotransferase greater than 4000 U/L) and prolo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199009000-00017
更新日期:1990-09-01 00:00:00
abstract::The temporary tissue expander can generate an excess of full-thickness skin that can be recruited into an adjacent area of tissue deficiency caused by scar contracture. The creation of a pseudobursa enhances the functional improvement gained by this technique. Now in its developmental stage, tissue expansion carries a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198604000-00011
更新日期:1986-04-01 00:00:00
abstract:BACKGROUND:Ventilator-associated pneumonia (VAP) is one of the most frequent infections in intensive care units (ICUs), and nearly 50% of patients with VAP develop septic shock. Septic shock is an independent predictor for mortality in these patients. OBJECTIVE:To investigate the predictors for septic shock in VAP pat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181827891
更新日期:2008-12-01 00:00:00
abstract::Interaction of allergen with T-cells is associated with patterns of cytokine release by immunocompetent cells characterized as T-helper Th1 or Th2 T-immune responses. The Th2 pattern of inflammation induced by this cytokine release is associated with allergic diseases. The molecular mechanisms underlying allergic infl...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.SMJ.0000097887.04639.39
更新日期:2003-11-01 00:00:00
abstract::Arsenic poisonings occur in Mississippi despite public education campaigns to prevent poisonings in the home. We reviewed 44 Mississippi cases of arsenic exposures occurring from January 1986 to May 1990. We compared the epidemiologic differences between unintentional and intentional poisonings. Cases were found and c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199104000-00012
更新日期:1991-04-01 00:00:00
abstract::We report the case of a term newborn with vein of Galen aneurysm. No antenatal diagnosis was done. The infant was admitted secondary to cardiac failure, with cardiomegaly and pulmonary hypertension. Physical examination was remarkable for acrocyanosis, microcephaly, cranial bruit, bilateral neck swelling, coarse breat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-200405000-00020
更新日期:2004-05-01 00:00:00
abstract::In 32 patients with the onset of myasthenia gravis after age 50, myasthenic crisis occurred in 53% and persisted for a mean of 33 days (range six to 84 days). Three of the patients had a second crisis. Precipitating factors were found in 60% of the episodes. Treatment of 20 episodes of crisis resulted in excellent rec...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198510000-00017
更新日期:1985-10-01 00:00:00
abstract::We have described a patient with vaccinia necrosum after smallpox vaccination for persistent herpes labialis. The patient eventually recovered after surgical resection of the lesion and multiple courses of vaccinia immune globulin and methisazone. This report emphasizes the needless risks of vaccinating patients with ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198103000-00044
更新日期:1981-03-01 00:00:00
abstract::Two cases of recurrent psychotic depression are reported in which ECT (electroconvulsive therapy) was administered with good results for previous episodes of depression, but treatment of the current episode with combined drug therapy (antidepressant and antipsychotic drugs) in one case and antidepressant chemotherapy ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197812000-00021
更新日期:1978-12-01 00:00:00
abstract::The ability of Clonorchis sinensis to cause severe hepatobiliary disease is illustrated by the case we have reported, in which biliary obstruction and hepatic fibrosis resulted from the pathologic process associated with chronic clonorchiasis. Immunodiagnostic tests are currently limited, and diagnosis, as illustrated...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198707000-00030
更新日期:1987-07-01 00:00:00
abstract::A technic of combined split-thickness and full-thickness skin grafts and local flap closure for extensive deep cicatricial neck contractures is presented. The head and neck are mobilized by excision of limiting tissues. The lateral neck skin is mobilized to be rotated anteriorly as flaps, and a full-thickness skin gra...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197606000-00023
更新日期:1976-06-01 00:00:00
abstract:OBJECTIVES:Despite the efforts of various leading organizations in medical education, representation of black students in US medical schools has declined since the mid-1990s. The Florida State University College of Medicine (FSUCOM) has undertaken efforts to increase black and other underrepresented minority in medicin...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000792
更新日期:2018-04-01 00:00:00
abstract::Serologic tests for the diagnosis of blastomycosis have had inadequate sensitivity, but results are improved with enzyme immunoassay (EIA) with A-antigen of Blastomyces dermatitidis. The Premier Blastomyces EIA kit (Meridian Diagnostics Inc, Cincinnati, Ohio) detected antibody against the B dermatitidis A-antigen in s...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199512000-00013
更新日期:1995-12-01 00:00:00
abstract::We have described a 6-day-old male infant who presented with Neisseria gonorrhoeae conjunctivitis and a scalp abscess. Delivery was complicated by rupture of the membranes 24 hours before delivery and fetal monitoring for four hours. The rare scalp abscesses caused by gonococci cleared with penicillin therapy. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198003000-00042
更新日期:1980-03-01 00:00:00
abstract::The predictability of a method of determining serum digoxin concentration was assessed in a retrospective study of 35 hospitalized patients taking digoxin orally for maintenance therapy. Simple pharmacokinetic expressions were used to estimate digoxin concentration. Clinically, the mean measured digoxin concentration ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198403000-00016
更新日期:1984-03-01 00:00:00
abstract::Single-agent chemotherapy (actinomycin D) was administered in cyclic regimens to 26 patients with metastatic, nonseminomatous testicular carcinoma. Twenty-five patients were evaluable, 9 with stage II disease and 16 with stage III disease. A 37.5% response rate in stage III disease is reported and all patients are lon...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197608000-00017
更新日期:1976-08-01 00:00:00
abstract::We report a case of perforated solitary jejunal diverticulum in an 80-year-old woman. Jejunal diverticulosis occurs in 0.07% to 2.0% of the population. Jejunal diverticulitis with perforation is rare and is associated with high mortality. Treatment is surgical resection of the involved segment. Several theories to exp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199505000-00013
更新日期:1995-05-01 00:00:00
abstract::A rare case of alveolar rhabdomyosarcoma of the urinary bladder, manifested as a systemic disease in a 51-year-old woman, was diagnosed at necropsy. Diffuse lytic bone lesions and extensive bone marrow involvement with a leukoerythroblastic blood picture led to an initial clinical diagnosis of a hematologic malignancy...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198704000-00031
更新日期:1987-04-01 00:00:00
abstract::Patients with recurrent thrombosis may have one of the thrombophilias described in recent literature. These clotting disorders may involve abnormalities in platelets, fibrinogen, plasminogen, protein C, protein S, or antithrombin III. There is usually a family history of clotting disorders, since most of these are inh...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:1988-10-01 00:00:00
abstract:OBJECTIVE:There is a relation between tumor stage and grade with the risk of cancer recurrence in patients undergoing surgical treatment for kidney cancer. The association of patient comorbidity with disease recurrence is less well characterized. The objective of this study was to explore the association between comorb...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000651
更新日期:2017-05-01 00:00:00
abstract::In a series of 60 consecutive patients in whom Hickman catheters were placed for treatment of malignancy, four properly positioned catheter tips migrated secondarily from the superior vena cava to the ipsilateral jugular vein 2, 4, 21, and 25 days after placement. Three of the four patients had begun to have catheter ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198511000-00014
更新日期:1985-11-01 00:00:00
abstract::Cladophialophora bantiana, a dematiaceous fungus, is an uncommon pathogenic organism originally thought to more commonly affect immunocompetent patients. Increasing numbers of reports, however, describe the organism affecting immunocompromised patients. Like all dematiaceous fungi, Cladophialophora can be recognized i...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e318164e289
更新日期:2008-03-01 00:00:00
abstract::We have reported a fatal complication of a therapeutic dose of ipecac syrup administered in a hospital emergency room. This child received 15 ml of ipecac syrup shortly after ingesting one to five tablets of chlorpheniramine maleate (4 mg). A prolonged course of vomiting (more than 24 hours) eventually resulted in gas...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198706000-00031
更新日期:1987-06-01 00:00:00
abstract::We have described three cases of adenomyoma of the stomach. These benign lesions are found almost exclusively in the antrum or pylorus and are composed of combinations of ducts, glands, pancreatic tissue, and smooth muscle. Malignancy arising in adenomyomas is rare. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198410000-00037
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the relation among multiple morbidities and the prevalence of colorectal cancer (CRC) screening among older adult Appalachian residents of Kentucky. This is the first known study to address multiple morbidities exclusively with a health-disparities population. METH...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31823a8879
更新日期:2011-12-01 00:00:00
abstract::We have described a patient with strangulation of a Meckel's diverticulum in a femoral hernia. In the case of Littre's hernia, true diagnosis before surgical intervention is rare if not impossible. It is therefore important that the surgeon be well versed in the management of such cases, as well as in distinguishing a...
journal_title:Southern medical journal
pub_type: 历史文章,杂志文章
doi:10.1097/00007611-198705000-00027
更新日期:1987-05-01 00:00:00