Abstract:
:Single-agent chemotherapy (actinomycin D) was administered in cyclic regimens to 26 patients with metastatic, nonseminomatous testicular carcinoma. Twenty-five patients were evaluable, 9 with stage II disease and 16 with stage III disease. A 37.5% response rate in stage III disease is reported and all patients are long-term survivors. Five of eight stage II patients currently being followed are alive and well. During toxicity was negligible. Actinomycin D is recommended as the initial drug of choice for metastatic testicular carcinoma.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Early KS,Albert DJdoi
10.1097/00007611-197608000-00017subject
Has Abstractpub_date
1976-08-01 00:00:00pages
1017-21issue
8eissn
0038-4348issn
1541-8243journal_volume
69pub_type
杂志文章abstract::In a retrospective review of one year's experience in the management of neck trauma, 88 cases comprising 42 gunshot wounds, 29 stab or slash injuries, and 17 injuries by blunt trauma were reviewed. Multiple injuries were noted in all groups, but a higher percentage was found in the blunt trauma series. Anesthetic mana...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00004
更新日期:1979-09-01 00:00:00
abstract::Interruption of the inferior vena cava by the transvenous placement of a filter or umbrella effectively prevents pulmonary embolism by acting primarily as a physical barrier to emboli. Such a device will be effective only if the site of thrombosis is distal to the planned placement site. We have presented two cases in...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198906000-00025
更新日期:1989-06-01 00:00:00
abstract::An instance of thyroglossal duct cyst in a 68-year-old man was reported. The clinical diagnosis of a thyroglossal duct cyst is suggested by the presence of a cystic mass situated anteriorly in the midline of the neck regardless of the patient's age. A review of the literature revealed that the incidence markedly decre...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197710000-00028
更新日期:1977-10-01 00:00:00
abstract::Cantharidin in either a 0.9% or 0.7% solution is a safe and effective office treatment for molluscum contagiosum. It simplifies the treatment, especially of children, by being a quick, simple, and painless procedure, but it should be applied only by the physician. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract::Millions of concussions occur every year in the United States. The public interest in concussion has increased after a number of high-profile deaths in high school athletes from sports-related head trauma and in some professional athletes from chronic traumatic encephalopathy. One of the most active areas of research ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0000000000000064
更新日期:2014-02-01 00:00:00
abstract::Fifty-four residents in internal medicine and primary care medicine were surveyed before and after receiving a prescription drugs price guide booklet to determine whether providing written price information to the residents would improve their knowledge of drug costs. Results indicated that the pricing information did...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198303000-00015
更新日期:1983-03-01 00:00:00
abstract::We reviewed the charts of 106 patients treated with carbamazepine. Age, sex, race, seizure type, seizure focus, age at onset, duration of epileptic illness, reasons for discontinuing treatment, other medications, and response to treatment of seizures, psychiatric symptoms, and behavioral symptoms were recorded. Statis...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199301000-00005
更新日期:1993-01-01 00:00:00
abstract::A 16-year-old white boy had nephrotic syndrome due to focal segmental glomerulosclerosis six months before the diagnosis of Hodgkin's disease was established. Peritoneal dialysis was necessary for volume control after one month of unsuccessful therapy with high doses of corticosteroids. Nephrosis remitted after two co...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198909000-00034
更新日期:1989-09-01 00:00:00
abstract::We have described a patient with community-acquired, methicillin-resistant Staphylococcus epidermidis endocarditis that occurred on a prolapsing mitral valve. The patient was successfully treated with vancomycin and rifampin for six weeks and had no signs of relapse four months later. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1983-09-01 00:00:00
abstract:BACKGROUND:Although dizziness is a common symptom in both primary care and referral practices, the relative frequency of various causes has not been well delineated. METHODS:A MEDLINE search identified 12 articles containing original data on the etiology of dizziness in consecutive patients. Study sites included prima...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2000-02-01 00:00:00
abstract::Keloid management remains controversial, and recurrence and untoward side effects limit the use of many techniques. During a seven-year period, I surgically treated 19 children, aged 3 to 17 (mean 10.5 years), with a total of 28 keloids. After aseptic skin preparation, the interface between the keloid and normal skin ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198806000-00013
更新日期:1988-06-01 00:00:00
abstract::This case study supports the plea by a number of psychiatrists for thorough psychiatric and psychologic screening of all persons seeking sexual reassignment surgery. The patient, a female impersonator taking estrogen, was seriously considering such an operation in order to cope with identity problems and an inability ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197504000-00017
更新日期:1975-04-01 00:00:00
abstract::Whereas painless gross hematuria in the hemophiliac is usually secondary to the basic coagulation defect, it is not always so. An elderly man presented with this clinical situation which, after a protracted course, was ultimately proven to be associated with an infarcted kidney. In retrospect, the patient's age and th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198207000-00029
更新日期:1982-07-01 00:00:00
abstract::The transition of care between pediatric and adult medicine is a challenging time for patients and physicians. This longitudinal process encompasses much more than the physical transfer of a patient between providers. Established transition of care processes and literature exist for many chronic disease populations, b...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000001017
更新日期:2019-09-01 00:00:00
abstract::Human immunodeficiency virus (HIV) has caused resurgence in tuberculosis (TB) worldwide. HIV-TB coinfected individuals are at increased risk for complications of TB and HIV treatment, such as adverse drug reactions and immune reconstitution syndrome. A 17-year-old male with HIV-TB coinfection, who developed cardiac ta...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181684b92
更新日期:2008-05-01 00:00:00
abstract::A 68-year-old male presented with progressive abdominal pain, dyspnea, weight loss, and dysuria. Lab work revealed elevated creatine phosphokinase levels, prostate-specific antigen level (approximately 60 ng/mL), and elevated liver enzymes. He was admitted to the intensive care unit for worsening respiratory distress ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31817c74c3
更新日期:2008-10-01 00:00:00
abstract::In an investigation of withdrawals and delays among students enrolled at the University of Tennessee College of Medicine over a four-year period, we found significantly higher rates of attrition among minority than nonminority students and among female than male enrollees. There were, however, no significant sex-relat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198105000-00025
更新日期:1981-05-01 00:00:00
abstract:BACKGROUND:The prevalence of smoking in the general US population has declined significantly over the past few decades. Despite this, few studies have examined changes in cigarette attributes perceived by less educated, rural, or southern populations. METHODS:A survey was administered to individuals in clinic waiting ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract::Gastrocolic fistulas are rare, and are usually seen as complications of peptic ulcer or malignancy of the stomach and large intestine. We have described a case resulting from chronic relapsing pancreatitis. The patient was successfully treated with excision of the fistula and closure of the gastric and colonic wall. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198910000-00030
更新日期:1989-10-01 00:00:00
abstract::Unremitting diarrhea is a common problem in patients with AIDS. We have reported the case of such a patient who was treated with the somatostatin analogue octreotide for chronic diarrhea and who had acute pancreatitis as a consequence of this therapy. We postulate that the possible mechanism for the pathogenesis of th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199111000-00035
更新日期:1991-11-01 00:00:00
abstract::From 1976 to 1982, 12 children with myelodysplasia had surgery at our institution for knee flexion contractures (21 affected knees). Follow-up was a minimum of 18 months and averaged 47 months. Soft tissue lengthening of the hamstring tendons and release of the posterior capsule with or without femoral osteotomy yield...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198607000-00009
更新日期:1986-07-01 00:00:00
abstract::We have described a case of hypophosphatasia with a mild progressive course. This condition and its familial propensity may be more prevalent than recognized. Thus, family members of a patient with hypophosphatasia should be screened for this disorder. Enthusiastic pharmacologic, hormonal, and/or dietary supplemental ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198312000-00030
更新日期:1983-12-01 00:00:00
abstract::We report the case of an 18-year old man with hemolytic-uremic syndrome (HUS) having a classic clinical presentation and diagnostic renal pathology without evidence of microangiopathic hemolytic anemia (MAHA) by peripheral blood smear. Indirect evidence of hemolysis was suggested by mild anemia, elevation of serum lac...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199603000-00018
更新日期:1996-03-01 00:00:00
abstract::Interaction of allergen with T-cells is associated with patterns of cytokine release by immunocompetent cells characterized as T-helper Th1 or Th2 T-immune responses. The Th2 pattern of inflammation induced by this cytokine release is associated with allergic diseases. The molecular mechanisms underlying allergic infl...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.SMJ.0000097887.04639.39
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:Airway failures are the second leading cause of potentially preventable death on the battlefield. Improvements in airway management depend on identifying current challenges. We sought to build on previously reported data on prehospital, combat airway management. METHODS:We used a series of emergency departm...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000906
更新日期:2018-12-01 00:00:00
abstract::In this paper we describe a technique for continuous spinal anesthesia, first described at the turn of the 20th century and long thought to have become obsolete. We discuss reasons for discontinuance and neglect of the technique, as well as its indications, applications, and specific advantages, and we report a signif...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198802000-00008
更新日期:1988-02-01 00:00:00
abstract::Catheter emboli are a significant risk to patient well-being. With a 49% complication rate for indwelling catheter emboli, the consensus is that these foreign bodies should be removed. Preferably, the emboli are removed by percutaneous extraction; however, if the emboli are in the heart or central vasculature and perc...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199607000-00013
更新日期:1996-07-01 00:00:00
abstract::Studies at "the Farm," a community of spiritually gathered young people in Summertown, Tenn, have shown that it is possible to sustain a normal pregnancy on a vegan diet. The source of dietary protein (ie, animal or vegetable) does not seem to affect birth weight, as long as vegans are health conscious, receive contin...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198706000-00007
更新日期:1987-06-01 00:00:00
abstract:OBJECTIVE:No standard therapeutic option exists for men with prostate cancer who have failed local therapy, have no gross metastatic disease, and whose only manifestation of disease is a rising prostate-specific antigen (PSA) level. Soy products are able to affect PSA kinetics in some men with prostate cancer, and this...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3182335151
更新日期:2011-11-01 00:00:00
abstract::The renin-angiotensin-aldosterone system (RAAS) plays a major role in blood pressure regulation and is thus an important therapeutic target in the management of hypertension. Angiotensin receptor blockers (ARBs), which interrupt RAAS overactivity by blocking a specific receptor that mediates the pathogenic activity of...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3181e1e2da
更新日期:2010-07-01 00:00:00