Adult respiratory distress syndrome.

Abstract:

:Treatment of the adult respiratory distress syndrome requires an understanding of the current concepts of the pathogenesis of this syndrome. The clinical features and pathophysiology are briefly discussed. Differential diagnosis requires the exclusion of pulmonary infection and left heart failure. Therapy is aimed at correction of the associated initiating disease process and the maintenance of tissue oxygenation. The latter requires increased inspired oxygen concentration, maintenance of an adequate cardiac output, and maintenance of a normal hematocrit level and body temperature. The therapeutic role of intravenous albumin, diuretics, and steroids in this syndrome is still controversial. Currently accepted modalities for improving oxygenation, when oxygen by face mask proves inadequate, include intubation and ventilation with postiive end-expiratory pressure. Other promising technics for improving oxygenation which do not require intubation are continuous positive airway pressure applied by face mask, continuous negative chest wall pressure, and alterations in posture. The long-term prognosis in survivors appears to be good, with only mild residual pulmonary functional abnormalities.

journal_name

South Med J

journal_title

Southern medical journal

authors

Burki NK

doi

10.1097/00007611-197811000-00028

subject

Has Abstract

pub_date

1978-11-01 00:00:00

pages

1412-5, 1423

issue

11

eissn

0038-4348

issn

1541-8243

journal_volume

71

pub_type

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