Abstract:
:Macular amyloidosis (MA) is a common form of primary localized cutaneous amyloidosis, characterized by the eruption of brown pigments of the skin with a rippled pattern. MA can be of cosmetic concern for patients, and its treatment is challenging. In this study, we aimed to find new effective approaches for MA treatment. A total of 39 patients with the clinical diagnosis of MA were treated with two types of laser therapy, and the effectiveness of each approach was examined. Fractional Q-switched 10.64 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser therapy was compared with a combination of fractional Q-switched 10.64 nm Nd:YAG laser and long-pulsed fractional erbium:YAG laser therapy. Melanin biometric measurements were performed using a Mexameter, objective image-based evaluation was carried out, and the itching score and patient satisfaction were examined. Mexameter-based analysis showed that both types of laser therapy were effective in the treatment of MA, causing a significant decrease in the amount of melanin in the treated areas (P < 0.05). Also, combination of two types of laser therapy was significantly more effective than one type alone (P < 0.05). The itching score significantly decreased in patients undergoing a combination of laser therapies. Also, a positive correlation was observed between the amount of melanin and degree of itching in the treated areas. Moreover, analysis of patient satisfaction showed that more than 90% of patients had excellent satisfaction with combination laser therapy. The results confirmed the significant positive effects of both fractional Nd:YAG laser alone and in combination with fractional erbium:YAG laser therapy considering the reduction in melanin content; however, combination of two types of laser therapy was more effective than one type alone. Trial registration: IRCT20080901001159N23.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Nilforoushzadeh MA,Zolghadr S,Heidari-Kharaji M,Alavi S,Mahmoudbeyk Mdoi
10.1007/s10103-020-02954-ysubject
Has Abstractpub_date
2020-07-01 00:00:00pages
1171-1177issue
5eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-020-02954-yjournal_volume
35pub_type
临床试验,杂志文章abstract::Compensatory hypertrophy (CH) occurs due to excessive mechanical load on a muscle, promoting an increase in the size of muscle fibers. In clinical practice, situations such as partial nerve injuries, denervation, and muscle imbalance caused by trauma to muscles and nerves or diseases that promote the loss of nerve con...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03095-y
更新日期:2020-07-07 00:00:00
abstract::The aim of this work is to analyze the effects of LED therapy at 940 nm or cold water immersion therapy (CWI) after an acute bout of exercise on markers of muscle damage and inflammation. Thirty-two male Wistar rats were allocated into four groups: animals kept at rest (control), exercised animals (E), exercised + CWI...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-1039-2
更新日期:2012-09-01 00:00:00
abstract::This study evaluated the microhardness and polymerization shrinkage of flowable resins that are cured using different light sources. Seven flowable resins and two light sources (diode-pumped solid-state (DPSS) laser (LAS) and Optilux 501 (OP)) were chosen for the study. To evaluate the microhardness, a mold (height: 2...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0964-4
更新日期:2012-07-01 00:00:00
abstract::The aim of the study was to investigate the effect of low-level 809 nm laser irradiation on the proliferation rate of human larynx carcinoma cells in vitro. Epithelial tumor cells were obtained from a laryngeal carcinoma and cultured under standard conditions. For laser treatment the cells were spread on 96-well tissu...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-003-0265-7
更新日期:2003-01-01 00:00:00
abstract::Primary hepatocellular carcinoma (HCC) and colon carcinoma are two of the most common clinical malignancies along with high morbidity and mortality. As low-power laser irradiation (LPLI) can induce cytotoxicity or cell apoptosis on several types of hyperplasia, LPLI may be a potential alternative treatment for gastroe...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02869-3
更新日期:2020-04-01 00:00:00
abstract::This study aimed to evaluate the surface changes caused in zirconia by different surface treatments and the influence of the surface treatment and cement selection on bonding to zirconia under aging. Sintered zirconia specimens were divided into five groups (n = 31) based on the surface treatment, namely, control, air...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1221-1
更新日期:2014-01-01 00:00:00
abstract::Bactericidal and detoxification effects of diode laser (DL) have been reported in periodontal treatment. The objective of this study was investigating the additional effect of DL with nonsurgical periodontal treatment on the red complex bacteria in type 2 diabetes mellitus (DM) patients with chronic periodontitis (CP)...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-020-02997-1
更新日期:2020-08-01 00:00:00
abstract::Endometriosis is a chronic disease affecting mainly women of the reproductive age. Its most common manifestations include impaired fecundity, pelvic pain, and dyschezia. Laparoscopic removal of endometriotic foci remains to be the gold standard for the treatment of endometriosis. More effective techniques of endoscopi...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1630-4
更新日期:2015-01-01 00:00:00
abstract::The present work evaluated the effects of LED light irradiation on the healing of the navels of neonatal dairy calves. Fifty-seven neonatal calves were divided into two groups. Animals had their umbilical stumps immersed in 10% iodine tincture for 60 s, and this process was repeated every 24 h for three consecutive da...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2283-x
更新日期:2017-09-01 00:00:00
abstract::The aim of this study was to verify the maximum number of repetitions, fatigue index, blood lactate concentration ([Lac]), and cardiac autonomic responses after LED irradiation (LEDI) in the ipsilateral and contralateral limb. Twelve male subjects (22.0 ± 3.86 years; weight 82.94 ± 12.58 kg; height 1.77 ± 0.05 m), phy...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-017-2391-7
更新日期:2018-02-01 00:00:00
abstract::Corrosiveness of enamel surfaces of Smartbleach, Opus White, Opalescense Xtra Boost and a gel containing titanium dioxide (TiO(2)) particles, activated either by a frequency doubled neodymium: yttrium-aluminum-garnet (Nd:YAG) laser (532 nm) or a diode laser (810 nm) was evaluated by environmental scanning electron mic...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0567-x
更新日期:2009-05-01 00:00:00
abstract::Photosensitizers belonging to the boron-dipyrromethenes (BODIPYs) class were recently found endowed with good efficacy in the antibacterial photodynamic therapy (aPDT) against both Gram-positive and Gram-negative bacteria. In this paper, we report on the remarkable adjuvant effect exerted in this respect by linear pol...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2345-0
更新日期:2018-08-01 00:00:00
abstract::Bone morphogenetic proteins (BMPs) are secreted signaling molecules belonging to the transforming growth factor-beta (TGF-beta) superfamily. The objective of this study was to determine how gallium-aluminum-arsenium (GaAlAs) 650 nm laser influenced the action of BMPs on bone defects created in rat femurs. The sample c...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0595-6
更新日期:2009-09-01 00:00:00
abstract::The aim of this study was to identify biochemical changes in sciatic nerve (SN) after crush injury and low-level laser therapy (LLLT) with 660 nm and 808 nm by Raman spectroscopy (RS) analysis. A number of 32 Wistar rats were used, divided into four groups (control 1, control 2, LASER 660 nm, and LASER 808 nm). All an...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2627-1
更新日期:2019-04-01 00:00:00
abstract:UNLABELLED:The aim of this study was to compare the effects of the pulsed-dye laser (PDL) at a wavelength of 585 nm with those at 595 nm in the treatment of post-surgical scars, starting on the day of suture removal. The study was a prospective, non-randomized, double-blind, controlled, clinical trial, set in an outpat...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-009-0698-8
更新日期:2009-09-01 00:00:00
abstract::Low-level laser therapy (LLLT) has proved to have biostimulating effects on tissues over which they are applied, therefore accelerating the healing process. Most studies in implantology were focused on a reduction of the duration of osseointegration. There exist few articles analyzing the potential effects of these th...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-015-1860-0
更新日期:2016-02-01 00:00:00
abstract::Photodynamic therapy (PDT) is used for the prevention and treatment of non-melanoma skin cancer. Until recently, clinically approved indications have been restricted to actinic keratoses, nodular and superficial basal cell carcinoma, and, since 2006, Bowen disease. However, the range of indications has been expanding ...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-009-0716-x
更新日期:2009-11-01 00:00:00
abstract::Epithelial cells play an important role in reparative events. Therefore, therapies that can stimulate the proliferation and metabolism of these cells could accelerate the healing process. To evaluate the effects of low-level laser therapy (LLLT), human keratinocytes were irradiated with an InGaAsP diode laser prototyp...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1057-8
更新日期:2013-02-01 00:00:00
abstract::We report the results of endoscopic laser therapy on 59 patients with upper gastrointestinal vascular ectasia. After 300 sessions, complications were two nonbleeding and three bleeding ulcers, treated successfully with endoscopic therapy. After treatment, blood transfusions were abolished in 61% and reduced in 22% of ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-006-0389-7
更新日期:2006-09-01 00:00:00
abstract::In this study, the impact of two-dimensional (2D) and three-dimensional (3D) vision on laparoscopic performance of novice surgeons is examined. Twenty-five novice surgeons were directed to complete four basic tasks from European Training in Basic Laparoscopic Urological Skills (E-BLUS) with both 2D and 3D systems in a...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1739-0
更新日期:2015-05-01 00:00:00
abstract::Skin flaps are still a matter of concern among surgeons, as failures can occur leading to flap necrosis. However, low-level laser irradiation has been reported as an effective tool to improve the viability of ischemic flaps, yet its mechanisms of action remain unclear. We investigated the effect of low-level laser irr...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-1011-1
更新日期:2012-05-01 00:00:00
abstract::The biodistribution and pharmacokinetics of meta-tetra(hydroxyphenyl)chlorin (mTHPC)(1) have been documented in humans, rats, dogs and rabbits. It has been demonstrated to be an effective photodynamic therapy agent for treatment of squamous cell carcinoma. Squamous cell carcinoma is a common feline neoplasm, causing s...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s101030200014
更新日期:2002-01-01 00:00:00
abstract::The bactericidal activity of a pulsed fibre-optic Nd-YAP laser on various strains of oral bacteria: Prevotella nigrescens, Streptococcus sanguis, Actinomyces viscosus (i), Fusobacterium nucleatum, Actinobacillus actinomycetemcomitans and Peptostreptococcus micros (i) was evaluated. A 200-μm optical fibre was placed in...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s101030050010
更新日期:1998-12-01 00:00:00
abstract::Interstitial laser Doppler flowmetry was used to measure the effect of interstitial laser-induced thermotherapy on local blood perfusion in normal rat liver in the peripheral treatment region elevated to hyperthermic temperatures. The Nd:YAG laser emitting at 1064 nm was utilised as heat generation source. The plane-c...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s101030050036
更新日期:1999-06-01 00:00:00
abstract::Low-energy laser irradiation (Ga-Al-As semiconductor laser, output 50 mW) was applied to rat osteoclast precursor cells for 1, 3, 6, or 10 min at 24-h intervals during the culture period. The number of tartrate-resistant acid phosphatase positive multinucleate cells was increased by approximately 1.3-fold in the 3- an...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-005-0368-4
更新日期:2006-04-01 00:00:00
abstract::Photodynamic rejuvenation therapy (PDRT) is a growing field in cosmetic dermatology. In this study, different sources of light (a yellow laser, a red laser and ultraviolet A (UVA) lamps) were used to activate a second-generation photosensitiser, hypericin. Uptake of hypericin was monitored over 24 h and efficacy of PD...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1115-2
更新日期:2013-02-01 00:00:00
abstract::The molecular changes in gene expression following ablative laser treatment of skin lesions, such as atrophic scars and UV-damaged skin, are not completely understood. A standardized in vitro model of human skin, to study the effects of laser treatment on human skin, has been recently developed. Therefore, the aim of ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2175-0
更新日期:2017-05-01 00:00:00
abstract::In this study, shear bond strength (SBS) of metal orthodontic brackets to porcelain following conditioning by Er:YAG (erbium-doped yttrium aluminum garnet) and Nd:YAG (neodymium-doped yttrium aluminum garnet) laser in comparison to conventional methods was evaluated. One hundred glazed porcelain discs with an upper ce...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0878-6
更新日期:2012-03-01 00:00:00
abstract::Several studies suggest a biomodulatory influence of low-level laser irradiation in the inflammatory and reparative processes of dental tissues. The aim of this study was to investigate the stimulatory effect of 808-nm laser irradiation on root development of rat molars and also to evaluate the histological reaction o...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0935-9
更新日期:2012-05-01 00:00:00
abstract::We evaluate the safety, efficacy, and oncological outcomes of early palliative photoselective vaporization of the prostate (PVP) by GreenLight high-performance system (HPS) 120-W laser in patients with acute urinary retention (AUR) induced by advanced prostate cancer (PCa). A total of 39 advanced PCa patients with AUR...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1252-7
更新日期:2013-09-01 00:00:00