Abstract:
PURPOSE:The purpose of this study was to characterize airway problems, speech outcomes, and facial growth in patients with Stickler syndrome undergoing cleft palate repair. METHODS:A retrospective, longitudinal study was performed at the Children's Hospital of Philadelphia on 25 patients with Stickler syndrome and 53 nonsyndromic patients with clefts of the secondary palate repaired between 1977 and 2000. Airway problems were characterized by the incidence of Pierre Robin Sequence (PRS) and the necessity for surgical airway management. Speech was analyzed using the Pittsburgh weighted values for speech symptoms associated with velopharyngeal incompetence (VPI). Longitudinal anthropometric measurements represented up to 12 years of longitudinal cephalofacial growth. RESULTS:Seventy-two percent of patients with Stickler syndrome were diagnosed with PRS, 55.6% of whom required surgical airway management. Conversely, 20.8% of nonsyndromic patients were diagnosed with PRS (P < 0.0001), 18% of whom required surgical intervention (P < 0.05). Speech outcomes were poorer in patients with Stickler syndrome with 40% demonstrating borderline VPI and 13.3% demonstrating VPI, compared with 21.8% and 9.1%, respectively, in the nonsyndromic group. Both groups exhibited significantly shallower upper and mid facial depths and wider upper facial breadths when compared with normal standards of facial growth. Although there was a tendency toward decreased facial depths in patients with Stickler syndrome relative to nonsyndromic patients, the differences were nonsignificant. CONCLUSIONS:Patients with Stickler syndrome show significant potential for early airway compromise and a poorer prognosis for speech outcome after cleft palate repair. Their cephalofacial growth does not differ significantly from that of nonsyndromic cleft palate patients.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Jackson OA,Kaye AE,Lee A,Minugh-Purvis N,Cohen MA,Solot CB,McDonald-McGinn D,Jawad AF,Zackai EH,Kirschner REdoi
10.1097/SAP.0000000000002114subject
Has Abstractpub_date
2020-06-01 00:00:00pages
665-671issue
6eissn
0148-7043issn
1536-3708journal_volume
84pub_type
杂志文章abstract::Three cases of hereditary lateral cervical fistulas are reported. The patients had lateral cervical fistulas bilaterally and different types of auricular malformations. The mothers of the patients also had lateral cervical fistulas. Moreover, one mother had bilateral microtias and the other mothers bilateral preauricu...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198805000-00009
更新日期:1988-05-01 00:00:00
abstract::The most common cause of nasal obstruction is chronic enlargement of the inferior turbinate bones. The variety of medical and surgical treatments available for this condition bears testimony to their frequent ineffectiveness and the frustration of the physician or surgeon caring for these patients. Removal or destruct...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197909000-00009
更新日期:1979-09-01 00:00:00
abstract::Burn units and experienced burn nurses are valuable, expensive resources that are underutilized when the burn census is low. Burn facilities can be used to treat other conditions or injuries to provide optimum wound management or to provide overflow intensive care unit beds. We studied via a questionnaire survey the a...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198911000-00008
更新日期:1989-11-01 00:00:00
abstract::Simultaneous breast augmentation and abdominoplasty through a transverse suprapubic incision offers women the opportunity to undergo body restoration with one operation, one anestheitc, one incision, and no scars on or near the breasts. Prompted by the earlier work of Planas [5] and others, we have performed this comb...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198004000-00004
更新日期:1980-04-01 00:00:00
abstract::Thirty cases of constriction band syndrome diagnosed and treated with surgery at Ramathibodi Hospital, Bangkok, during 1973 to 1986 are reported. The incidence of this congenital anomaly could not be verified in this series because the number of cases was limited and the cause could not be concluded. The less frequent...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198811000-00017
更新日期:1988-11-01 00:00:00
abstract::The reverse sural artery flap is frequently used for reconstruction of the distal third of the leg, ankle, and heel. The major disadvantage of the flap is compression of the pedicle within the subcutaneous tunnel and venous congestion. Others have cited a decrease in this problem by harvesting a midline cuff of gastro...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:2005-03-01 00:00:00
abstract::Plastic surgeons with a practice that includes breast augmentation, breast reduction, and breast reconstruction should have a working knowledge of both genetic and environmental breast cancer risk factors and of risk stratification of these patients. Specific tests to determine genetic susceptibility to certain cancer...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200045050-00017
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Most head and neck melanomas occur on the face, with the cheek being the most frequently affected site. So far, small numbers of researches on cheek melanomas have yielded insufficient and controversial results. In this trial, we aimed to define the histopathological and clinical features specific to cheek m...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001695
更新日期:2019-04-01 00:00:00
abstract::Possessing viscous and elastic rheological properties, skin is viscoelastic. Mechanical creep, defined as the elongation of skin with a constant load over time beyond intrinsic extensibility, has been described as the vehicle harnessed for wound closure with presuturing, intraoperative tissue expansion, skin-stretchin...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-199808000-00019
更新日期:1998-08-01 00:00:00
abstract::Facial contours are thought to depend on the appropriate balance of hard and soft tissue. To obtain aesthetically good results in head and neck reconstruction, surgeons should know the exact three-dimensional shape and volume of both hard and soft tissue to be reconstructed. The authors used computer-assisted three-di...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200104000-00006
更新日期:2001-04-01 00:00:00
abstract::B vitamins rescue cleft palate induced by glucocorticoids in rodents; however, the mechanism of this effect remains largely unknown. The objective of our study was to assess the effect of dexamethasone and Vitamin B12 on cell proliferation and apoptosis during palatogenesis. In our study, mesenchymal cell proliferatio...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181b4bc8d
更新日期:2010-04-01 00:00:00
abstract:INTRODUCTION:Allograft use has increased recently with the rising use of allograft materials in breast surgery. There are few data that compare the performance of the various allograft materials in this application, despite marketing efforts by the manufacturers to present one allograft material as superior to another....
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318281aece
更新日期:2013-09-01 00:00:00
abstract::A superior advantage of the superficial circumflex iliac artery perforator flap is that any donor site residue can easily be hidden by clothing. Usually designed as narrow or moderate-sized flaps based on medial perforators of the superficial branch, this readily allows primary donor site closure. However, for larger ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002159
更新日期:2020-08-01 00:00:00
abstract::Twenty-five feet (18 patients) plus 2 traumatically amputated feet were used for angiographic analysis of the first metatarsal arteries. The author classified the first (dorsal and plantar) metatarsal arteries into three types: the first dorsal metatarsal artery, dominant type (seen in 17 feet), the first plantar meta...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198107000-00002
更新日期:1981-07-01 00:00:00
abstract:BACKGROUND:Evidence suggesting that adipose tissue is a metabolically active tissue has generated debate on the effects of large-volume liposuction (LVL) on metabolic and cardiovascular health. Given the inconsistency in the literature, the authors performed a systematic review to identify available evidence in order t...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0000000000001195
更新日期:2017-12-01 00:00:00
abstract::Limited data of body image and quality of life are available after panniculectomy. Although it is generally considered a medically necessary procedure, we believe that the benefits of this procedure are many. The Short Form of The Situational Inventory of Body Image Dysphoria Short Form and the Multidimensional Body S...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31820b3af6
更新日期:2011-05-01 00:00:00
abstract::Reconstruction involving seven venous flaps on six patients was performed. One saphenous venous flap demonstrated partial dermal necrosis; the remaining six survived completely. The largest flap to survive was 5 x 15 cm. Three technical requirements are emphasized; (1) a healthy recipient bed, (2) a donor site with a ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199505000-00011
更新日期:1995-05-01 00:00:00
abstract:PURPOSE:To study the availability and effects for application of 4 kinds of perforator flaps in repairing skin and soft tissue defects in different positions around the knee joints. METHODS:The present study included 26 cases (16 males and 10 females) with soft tissue defects with ages from 7 to 82 years who came to o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001544
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION:Indications for prophylactic antibiotic therapy in nonoperative, closed fractures of the orbit and zygoma remain controversial and are based on anecdotal data. The purpose of this study was to report the incidence of infectious sequelae among patients who presented to our institution with stated fractures ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002572
更新日期:2020-10-28 00:00:00
abstract::Previous work in our laboratory has indicated that ischemic preconditioning improves musculocutaneous flap survival 2.5 times that of the control flap area when the flaps are subsequently subjected to 4 hours of global ischemia. The preconditioning protocol used in this study was arbitrarily designed to be 10 minutes ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199804000-00018
更新日期:1998-04-01 00:00:00
abstract::Primary nerve grafting in traumatic injuries is rarely performed because of the uncertainty of the extent of injury, the limited availability of nerve grafts, and the damage to adjacent soft tissue. In this report the authors present two cases of acute nerve grafting after trauma-the first of the common peroneal nerve...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200111000-00015
更新日期:2001-11-01 00:00:00
abstract:PURPOSE:We had reported the surgical outcome of reverse skin redraping technique for restoration of previously performed epicanthoplasty. In this study, we introduce a modified reverse skin redraping technique that added mini-epicanthoplasty in patients with unsatisfactory results after epicanthoplasty. METHODS:Three ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000991
更新日期:2017-06-01 00:00:00
abstract::Lip augmentation is a well tolerated procedure that can lead to a more youthful appearance. Autologous tissue offers the safest and most long lasting results. Recently, a new source of autologous tissue, breast implant capsule, was described in the performance of permanent lip augmentation. Long term data in thirteen ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199803000-00012
更新日期:1998-03-01 00:00:00
abstract::Breast reconstruction after nipple sparing mastectomy (NSM) plays, nowadays, a fundamental role in breast cancer management. There is no consensus on the best implant-based reconstruction technique, considering 2 stages (expander-prosthesis) or direct-to-implant (DTI). A retrospective review of consecutive adult femal...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001893
更新日期:2019-10-01 00:00:00
abstract::We have developed a new in vivo model for the study of fetal wound healing. Fetal ICR mice (total gestation, 21 days) received a full-thickness incisional wound in the hind limb at gestational day 14 (N = 100). The wound was made with a 28.5-gauge needle that was passed transplacentally into the amniotic cavity. The w...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199710000-00008
更新日期:1997-10-01 00:00:00
abstract::This study reviewed the fate of titanium plates used to correct maxillofacial trauma in 76 patients to define risk factors for plate removal. Medical records of 76 consecutive patients at a single institution, over a 10-year period, were retrospectively reviewed. Variables included age, sex, trauma type, diagnosis, fr...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000183802.38116.37
更新日期:2005-12-01 00:00:00
abstract::Incisional hernias develop in 2% to 11% of patients who undergo laparotomy. Prosthetic mesh repair provides more strength, tension-free closure, and decreased recurrence rates as compared to primary tissue repairs. Complications-fistula formation, adhesions, skin erosion, and seroma/abscess formation-however, include ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318212f380
更新日期:2012-02-01 00:00:00
abstract::The use of the nasoalveolar molding technique (NAM) aims to reduce passively the width of the alveolar gap, while improving the AP discrepancy but also focusing on the nose. We developed a within-subjects study in which 11 infants with unilateral lip deformity and varying degrees of alveolar gaps were treated by NAM. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000259001.98869.d8
更新日期:2007-11-01 00:00:00
abstract::Tight abdominal closures, as can be seen during transverse rectus abdominis musculocutaneous (TRAM) flap breast reconstruction, have been shown to increase intra-abdominal pressure, thereby decreasing thoracopulmonary compliance and increasing the workload of breathing. The purpose of this article was to quantitate pu...
journal_title:Annals of plastic surgery
pub_type: 临床试验,杂志文章
doi:10.1097/SAP.0000000000000310
更新日期:2016-01-01 00:00:00
abstract::The growth of vascularized onlay bone (autogenous) transfers on the skulls of 27 newborn New Zealand white rabbits was studied. Freeze-dried bone weight in control newborns and control adults (group 1) was compared with that in experimental adult animals (group 2). In the experimental group, the bone was transferred o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198706000-00008
更新日期:1987-06-01 00:00:00