Abstract:
:B vitamins rescue cleft palate induced by glucocorticoids in rodents; however, the mechanism of this effect remains largely unknown. The objective of our study was to assess the effect of dexamethasone and Vitamin B12 on cell proliferation and apoptosis during palatogenesis. In our study, mesenchymal cell proliferation in mouse embryonic palates decreased when the subjects were administered dexamethasone at embryo day 13.5 (E 13.5). However, mesenchymal cell proliferation was increased after dexamethasone exposure at E 14.0 and E 14.5 in comparison with the control group. After Vitamin B12 treatment, proliferation of mesenchymal cells was restored. No apoptosis was detected until bilaterial palatal shelves adhered and formed a medial epithelium seam in the control group and Vitamin B12-treated group. However, the apoptotic cells were detected under the medial edge epithelium before the palate contacted after dexamethasone treatment. The results suggested that Vitamin B12 restored proliferation, which had been reduced by dexamethasone via a delayed cellular cycle and apoptosis. This study implies that Vitamin B12 may be used to prevent or alleviate cleft palate induced by dexamethasone during embryonic palatogenesis.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
He W,Meng T,Lu SJ,Zheng Q,Li CH,Wu M,Shi Bdoi
10.1097/SAP.0b013e3181b4bc8dsubject
Has Abstractpub_date
2010-04-01 00:00:00pages
466-70issue
4eissn
0148-7043issn
1536-3708journal_volume
64pub_type
杂志文章abstract::Piezoelectric sensors have been shown to respond reproducibly to changes in tissue mechanical properties surrounding an implant over a 4-month period. The vibrational amplitude at a frequency corresponding to the radial resonance shows a statistically significant change over time. The initial period of inflammation is...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000189620.45708.5f
更新日期:2006-01-01 00:00:00
abstract::Management of soft-tissue defects over the Achilles tendon presents specific challenges to the plastic surgeon. Primary closure or local flaps are often not feasible repair options for such wounds, and many of these patients may be poor candidates for free-tissue transfer secondary to their comorbidity. In this case s...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000181342.25065.60
更新日期:2005-10-01 00:00:00
abstract::The authors describe the ability of the gracilis muscle to provide multiple tissue components- skin, muscle, nerve, and tendonin the reconstruction of a complex dorsal foot wound resulting from a sarcoma resection. The deficits of skin, deep peroneal nerve, anterior tibialis tendon, and dorsal extensor retinaculum wer...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200103000-00023
更新日期:2001-03-01 00:00:00
abstract::Myxoma of the jaw is a rare, benign bone tumor of odontogenic origin. Given the locally aggressive nature of the myxoma and the high rate of recurrence, there is a tendency to choose radical resection of the jaw segment containing the tumor mass as the treatment modality. As they appear to attain a considerable size p...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199707000-00016
更新日期:1997-07-01 00:00:00
abstract::Using a newly developed Doppler probe, we have found that a standard suture anastomosis in a rat femoral artery is accompanied by significant (30-60%) cross-sectional area stenosis, which dissipates to baseline levels within 24 hours. We hypothesized that spasm, deposition of coagulation products, or the suture techni...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199503000-00015
更新日期:1995-03-01 00:00:00
abstract::Four cases of unilateral temporomandibular (TM) joint ankylosis were successfully treated by metatarsophalangeal to TM joint replacement by microvascular technique. Results 6 to 20 months postoperatively were encouraging. Further follow-up studies are necessary to evaluate the long-term results. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198512000-00008
更新日期:1985-12-01 00:00:00
abstract::The trapdoor deformity has been thought to be the result of contraction of the semicircular scar of the skin surface. The hypothesis is presented that a sheet of internal scar is primarily responsible for raising the skin inside the semicircle. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199008000-00011
更新日期:1990-08-01 00:00:00
abstract::Gout is a disease characterized by abnormal metabolism of the uric acid, leading to undesired buildup of monosodium urate crystals affecting mainly the first metatarsal-phalangeal joint of the foot and less commonly other joints or the soft tissues of the body. The prevalence of the disease increases with age, and it ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0000000000001778
更新日期:2019-06-01 00:00:00
abstract::The history of functional motor recovery after reconstruction of traction injury to the common peroneal nerve is poor, regardless of technique and regardless of the experience of the surgeon doing the reconstruction. The hypothesis tested is that the failure of functional motor recovery after common peroneal nerve tra...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3180302668
更新日期:2007-09-01 00:00:00
abstract::Lipofibromatosis is a slow-growing, childhood soft-tissue neoplasm that is often confused with other conditions. We report a patient with lipofibromatosis causing extremity enlargement at birth. The lesion initially was thought to be a vascular anomaly or lipedema on clinical and MRI examination. When involving the lo...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181a13df6
更新日期:2009-06-01 00:00:00
abstract::Deeply invading tumors of the scalp present numerous extirpative and reconstructive problems requiring the combined expertise and skills of both medical and surgical disciplines. We have employed a combined multidisciplinary approach to recurrent tumors of the scalp and calvarium. Intraoperatively, a fresh-tissue mapp...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::In 1994, Suzuki et al proposed the pins-and-rubbers traction system, a new dynamic distraction technique for difficult complex intra-articular fractures of the digits of the hand. From February 1999 to April 2003, we used the Suzuki frame for 15 complex fractures of the proximal interphalangeal joint of the fingers. T...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000244975.89885.c7
更新日期:2007-05-01 00:00:00
abstract:ABSTRACT:Subungual exostosis is a benign tumor that occurs under the nail plate of the distal phalanx and causes nail deformity and pain. There are many reports of recurrence and postoperative nail deformity, and the surgical approach needs to be reassessed. Two typical surgical approaches are from the nail fold and th...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002619
更新日期:2020-12-15 00:00:00
abstract::Beckwith-Wiedemann syndrome (BWS) is a complex overgrowth disorder usually recognized at birth. Children diagnosed with BWS, particularly those with hemihypertrophy, experience an increased risk of developing benign and malignant tumors. This case report presents a 12-year-old girl with BWS and hemihypertrophy who rap...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/sap.0b013e3181b025f6
更新日期:2010-06-01 00:00:00
abstract::Plastic surgeons have traditionally perceived male patients as more psychologically disturbed than female patients. This study employed a matched sample design to explore the psychosocial experiences of 50 male and 50 female elective cosmetic surgery and cosmetic dentistry patients. It also aimed to compare male and f...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181a72f50
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:The recent rise in medical tourism, especially for cosmetic procedures, has been mirrored by an increase in the incidence of infections with Mycobacterium abscessus, which is an atypical mycobacterium that is ubiquitous in aquatic environments. M. abscessus soft tissue infections arise from the use of improp...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002061
更新日期:2020-03-01 00:00:00
abstract::The arcuate line is a relevant structure when reconstructing the abdominal wall after rectus abdominis musculocutaneous flap harvest. Its location is classically taught to be half the distance from the pubic symphysis to the umbilicus, but recent anatomic literature provides evidence to the contrary. Better understand...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000112285.44287.21
更新日期:2004-08-01 00:00:00
abstract::A bayonet-shaped airway allowing free respiration and undisturbed deglutition was reconstructed in 2 young women who had undergone tracheotomy and radiotherapy for thyroid carcinoma. The laryngeal vestibule, glottis, and subglottis had been destroyed, and the air passages were closed. An external gutter and an anterio...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198605000-00010
更新日期:1986-05-01 00:00:00
abstract::The effect of a levator retrodisplacement procedure upon conductive hearing loss in cleft palate patients was evaluated. Forty-two children with cleft palates, operated upon between 1970 and 1975, were included in the study. The results suggest that 73.5% of those in the levator retrodisplacement group achieved normal...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198304000-00008
更新日期:1983-04-01 00:00:00
abstract:INTRODUCTION:The reconstruction of the postburn contracture area is always a challenge in the field of plastic surgery. Moreover, the joints are very sensitive to trauma and immobilization, showing a susceptibility to stiffness. The aim of this article is to emphasize the use of "Namaste flap"-modification of subcutane...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002076
更新日期:2019-12-01 00:00:00
abstract::The narrowness of the temporomandibular joint (TMJ) can cause difficulty in open reduction and fixation of condylar fracture. The authors designed a silicone block that acts as a fulcrum to create more space around the TMJ. The block is made of high-quality silicone that is firm, elastic, nontoxic, autoclave tolerant,...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199811000-00006
更新日期:1998-11-01 00:00:00
abstract::Capsular contracture is one of the most common complications resulting from implants placed during mammoplasty and rhinoplasty, and there is no definitive solution or a method for preventing it. Recent reports suggest that botulinum toxin A (BoTA) is effective at reducing keloid scars clinically. Peri-implant capsules...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318295de95
更新日期:2015-04-01 00:00:00
abstract::Biologic prostheses have emerged to address the limitations of synthetic materials for ventral hernia repairs; however, they lack experimental comparative data. Fifteen swine were randomly assigned to 1 of 3 bioprosthetic groups (DermaMatrix, AlloDerm, and Permacol) after creation of a full thickness ventral fascial d...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181e051ed
更新日期:2011-04-01 00:00:00
abstract::Multiple studies have compared the outcome of surgery for cubital tunnel syndrome (CUTS), yet there remains no clear guidelines for treatment. We describe an approach to CUTS that includes tailoring the procedure to the pathology found at surgery. Patients treated surgically were retrospectively reviewed. Following in...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318219183d
更新日期:2011-06-01 00:00:00
abstract::Our study of experimental contracture in rats confirms the existence in laboratory animals of a phenomenon very much like human capsule contracture. The ultrastructural features of capsules in rats are essentially identical to those for humans and rabbits. Macrophages with silicon-containing material were present. Sta...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198103000-00003
更新日期:1981-03-01 00:00:00
abstract::Avulsion fractures can pose technical difficulties for surgical fixation. The fragments are often small and around finger joints with access being difficult due to attachment of ligaments or tendons. Traditionally, these have been treated using K wires, lag screws, or pullout sutures.Hook plates were originally descri...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001119
更新日期:2017-09-01 00:00:00
abstract::The purpose of this study was to investigate nose maturation by cephalometric sagittal surface area methodology longitudinally in males and females. Both males and females exhibited a statistically significant continuum of nose growth from ages 6 to 18. Growth ceased in both sexes at age 18. Correlation coefficients i...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198704000-00007
更新日期:1987-04-01 00:00:00
abstract::Despite the advances in laser treatment of port wine stains (PWS), re-emergence of these lesions still occurs. We carried out a retrospective audit of all children that received laser treatment of PWS between 1997 and 2000 using the flashlamp-pumped dye laser with a 585-nm wavelength. Out of 110 patients treated, 15 r...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000221620.83178.fc
更新日期:2006-09-01 00:00:00
abstract::Out of 262 hands with total finger amputations treated by replantation of finger/fingers from January 2001 until January 2006, there were only 6 cases of type III ring avulsion injuries, all of which were replanted. Radical resection of the damaged part of the artery with primary vein grafting was used in each case; o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000252717.88972.01
更新日期:2007-08-01 00:00:00
abstract::Eight patients with fronto-orbito-sphenoidal fibrous dysplasia, aged between 9 and 37 years, half of them male, were radically or nearly radically excised with immediate autogenous bone graft reconstruction. They had had frontal bulging and proptosis on the affected sides for 3 to 20 years. Four had decreased vision o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198509000-00002
更新日期:1985-09-01 00:00:00