The use of biomedical sensors to monitor capsule formation around soft tissue implants.

Abstract:

:Piezoelectric sensors have been shown to respond reproducibly to changes in tissue mechanical properties surrounding an implant over a 4-month period. The vibrational amplitude at a frequency corresponding to the radial resonance shows a statistically significant change over time. The initial period of inflammation is marked by a significant reduction in amplitude, which is indicative of an increase in viscous dissipation of the tissue. As collagen displaces the cellular response, the amplitude continues to decrease. Finally, as the tissue matures, the capsule becomes stiffer, and the viscous dissipation lessens. These results are consistent with qualitative assessments of explanted capsules. Strain gauges encased in a monolithic block of silicone exhibited a greater degree of variability, yet show similar trends over time. The strain increases in the initial 4-week period and remains relatively steady over the following 4 weeks. Beyond 8 weeks, the gauges begin to extrude from the animal or suffer a loss of electrical continuity. Steps are being taken to improve the strain sensor longevity in the animals.

journal_name

Ann Plast Surg

authors

Bender JW,Friedman HI,Giurgiutiu V,Watson C,Fitzmaurice M,Yost ML

doi

10.1097/01.sap.0000189620.45708.5f

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

72-7

issue

1

eissn

0148-7043

issn

1536-3708

pii

00000637-200601000-00014

journal_volume

56

pub_type

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