Abstract:
:Previous work in our laboratory has indicated that ischemic preconditioning improves musculocutaneous flap survival 2.5 times that of the control flap area when the flaps are subsequently subjected to 4 hours of global ischemia. The preconditioning protocol used in this study was arbitrarily designed to be 10 minutes of pedicle clamping followed by 10 minutes of reperfusion. This sequence was repeated for three cycles with a total preconditioning time of 1 hour. There are no published works comparing different preconditioning protocols in musculocutaneous flaps. The goal of this study was to determine if the ischemic cycle time and the number of cycles influenced the effectiveness of ischemic preconditioning. Fifty-one male Sprague-Dawley rats were divided into one control and six treatment groups of 6 to 10 animals in each group. A transverse rectus abdominis musculocutaneous flap based on the inferior epigastric vessels was elevated in each animal. Flaps were preconditioned by pedicle clamping and reperfusion for either 5 or 10 minutes per cycle. This was repeated for one, two, or three cycles. Controls were simply perfused for 30 minutes. Each flap was then subjected to 4 hours of global ischemia. Flap surface survival area was calculated on the fifth postoperative day by computerized video planimetry. Differences in survival areas between control and preconditioned flaps were compared using analysis of variance and t-tests. There was an overall statistical significance in the comparison of flap survival of preconditioned flaps with that of controls. A single 5-minute cycle improved flap survival 2.5 times the mean control area. Two and three 5-minute cycles resulted in a reduction of the preconditioning effect, with flap survival no different than controls. Ten-minute preconditioning cycles increased flap survival 1.5 to 3 times the mean control area. Flap survival was improved by increasing the number of 10-minute cycles. Cycle time and number of cycles have definite effects on the survival areas of preconditioned musculocutaneous flaps. Ischemic preconditioning with 10-minute cycles is superior to 5-minute cycles. Three cycles of 10-minute preconditioning is statistically superior to one or two cycles. Future studies are planned to study four or more cycles and longer cycle times.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Zahir TM,Zahir KS,Syed SA,Restifo RJ,Thomson JGdoi
10.1097/00000637-199804000-00018subject
Has Abstractpub_date
1998-04-01 00:00:00pages
430-5issue
4eissn
0148-7043issn
1536-3708journal_volume
40pub_type
杂志文章abstract::A patient who sustained frontal sinus fracture and who earlier had undergone an osteoplastic fat obliteration procedure is described. The literature is reviewed and recommendations are made for management of this and other cases of frontal sinus fractures with posterior table involvement. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-198608000-00012
更新日期:1986-08-01 00:00:00
abstract::Metastatic spread of head and neck cancer signifies a grave change in prognosis for the patient. The presence or absence of detectable metastasis is valuable knowledge both in planning treatment and in predicting prognosis. Knowledge of the metastatic behavior patterns of such tumors, and of the diagnostic means of de...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198005000-00008
更新日期:1980-05-01 00:00:00
abstract::Surgical procedures commonly associated with parenteral sedation or general anesthesia were completed in an office operating room with local anesthesia and oral medication. Diazepam and alprazolam were used in combination to produce a relaxed state, allowing local anesthesia to be instilled. Surgery was completed succ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200044050-00007
更新日期:2000-05-01 00:00:00
abstract::Internal and external diameters of sections of radial and ulnar arteries obtained from fresh cadavers were measured. Statistical analysis of the results obtained shows significant correlation (p less than 0.05). The wide range of values obtained suggests that, despite this degree of correlation, the internal diameter ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198709000-00006
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND:The facial dismasking flap (FDF) approach to operations on the deep skull base region consists of a coronal incision and a circumpalpebral incision. This approach provides a wide surgical field for extirpation of deep extended craniofacial tumors without leaving any undesirable scars on the face. Therefore, ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000662
更新日期:2017-01-01 00:00:00
abstract::Soft tissue defects in the periolecranon region are difficult to manage by standard techniques such as closure by approximation, split-thickness skin grafting, or healing by secondary intention. We employed cadaver injections and dissections to study the vascular anatomy of the periolecranon region in search of a suit...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198504000-00010
更新日期:1985-04-01 00:00:00
abstract:BACKGROUND:Whether postoperative care in the intensive care unit (ICU) is a necessity for patients undergoing head and neck free flap reconstruction remains debatable. In August 2012, our institute initiated a policy to care for these patients in the ICU, opposed to the previous policy of care in the ward. Thus, we use...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001301
更新日期:2018-02-01 00:00:00
abstract::We present an original technique of transposition of the fifth ray by intracarpal osteotomy. After a review of various techniques and their disadvantages, the principles of the procedure are described. It includes a resection of the whole fourth ray and translocation of the fifth ray following a wedge-shaped osteotomy...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198609000-00009
更新日期:1986-09-01 00:00:00
abstract:BACKGROUND:Early hepatic artery (HA) thrombosis and primary graft failure contribute greatly to the mortality of patients after liver transplantation. Herein, we present the treatment of intimal injury of HA by intraoperative fluorescence vascular stenting. METHODS:A sample of 471 patients receiving liver transplantat...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001899
更新日期:2019-08-01 00:00:00
abstract::Hemangioma of the zygomatic bone is an extreme rarity. Six cases have been reported in the English literature. These reports and the 2 new patients presented here constitute the basis for our data. Clinical, histopathological, therapeutic, and reconstructive considerations are discussed. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198706000-00013
更新日期:1987-06-01 00:00:00
abstract::In the absence of clinically positive regional nodes, any value of prophylactic dissection in malignant melanomas depends on accurate preoperative determination of the pathway of lymphatic drainage. We report on the use of noninvasive radionuclide lymphoscintigraphy in the determination of regional patterns of lymph n...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract::Since 1993, a total of 41 free osteofasciocutaneous fibular flaps with an extended skin island (average dimensions, 16.9 cm long [range, 12-22 cm] x 10.7 cm wide [range, -16 cm], or 180.8 cm [range, 112-352 cm ]) have been used in by the authors in various clinical applications. To evaluate donor site morbidity, the 4...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200208000-00005
更新日期:2002-08-01 00:00:00
abstract::Hypertrichosis is an often stigmatizing cosmetic problem not only for women but also for male-to-female transsexual patients. The hitherto described therapeutic measures include chemical epilation, razoring, camouflage, electrolysis and thermolysis, and waxing. All of these measures are transient, more or less painful...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199708000-00009
更新日期:1997-08-01 00:00:00
abstract::Prosthetic graft material is often used for the repair of abdominal wall defects that result from trauma, infection, neoplastic, or congenital deformities. A new material, porcine small intestinal submucosa, has been successfully used as an arterial and venous graft material in both canine and primate animal models wi...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract::Thirteen breast reconstructions in 11 patients, averaging 58 years of age, underwent mastectomies. The technique uses a saline implant either totally or partially covered with a human acellular dermal matrix. The mean postoperative follow-up time was 14 months. Ninety percent of the patients were considered high risk;...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000185460.31188.c1
更新日期:2006-01-01 00:00:00
abstract::Although microsurgery has rapid expanded, problems related to microarterial anastomosis continue. Cigarette smoking is one of the major risks for anastomosis by increasing platelet adhesion, and its effects on endothelial cells. Aim of this article is to study the negative effects of cigarettes on microarterial anasto...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181b404fa
更新日期:2010-07-01 00:00:00
abstract::Peripheral nerve gap injuries continue to present a clinical challenge to today's surgeons. One method of surgical repair, implantation of acellular allografts, has been developed with the aim of bridging the gap with a cadaveric graft after removal of its cellular components, thereby accelerating axonal regeneration ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001464
更新日期:2018-08-01 00:00:00
abstract::The repair of intractable ulcer over the Achilles' tendon in a patient with Werner's syndrome is described. The ulcer was covered successfully with a lateral supramalleolar flap combined with a delay procedure. Partial necrosis of the flap occurred; however, the necrotic area could be repaired with a skin graft becaus...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199809000-00015
更新日期:1998-09-01 00:00:00
abstract::Neurocutaneous flaps are utilized routinely in reconstructive surgery and even more so during the past decade. In this study, the vascular supply of the neurocutaneous flap in the rat model is presented and evaluated. Thirty-six flaps (3.5x3 cm2) were dissected on the medial aspect of the leg based on a pedicle of the...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199910000-00012
更新日期:1999-10-01 00:00:00
abstract:INTRODUCTION:Plantar hyperkeratosis, such as corns and calluses, is common in older people and associated with pain, mobility impairment, and functional limitations. It usually develops on the palms, knees, or soles of feet, especially under the heels or balls. There are several treatment methods for plantar hyperkerat...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001304
更新日期:2018-02-01 00:00:00
abstract::The purpose of this pilot study was to compare proliferation, collagen synthesis, and growth factor production, which are important contributing factors for wound healing, of the bone marrow stromal cells (BSCs) with those of dermal fibroblasts in vitro. Cultured human BSCs and dermal fibroblasts from the same patient...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000178809.01289.10
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Current trends in the management of medial orbital wall fractures are toward the development of transconjunctival incisions and the use of endoscopic-assisted methods. Different authors have suggested variations of the medial transconjunctival approach. METHODS:(1) In 30 fresh cadaver orbits, the classic tr...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000531
更新日期:2016-03-01 00:00:00
abstract::A semiautomatic anthropometric caliper was developed to accelerate and simplify anthropometric data acquisition. A technical slide caliper, connected via optical data cable interface to a standard PC, was amended with a data-input switch. A data sheet was filled in with consecutive measurements in 30 volunteers and co...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000238344.15224.33
更新日期:2007-06-01 00:00:00
abstract::Many techniques for cleft lip repair have been reported, but these techniques do not consider the contour lines of the upper lip and, in fact, destroy them. The upper lip has complicated contour lines including the vermilion free margin, vermilion border, upper lip horizontal groove (upper lip groove), philtrum (dimpl...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199109000-00008
更新日期:1991-09-01 00:00:00
abstract::This is a short clinical report depicting an exceptionally early presentation of radiation-induced angiosarcoma and overview of the literature. This case highlights the need for a high level of clinical suspicion in those patients presenting with unresolving cutaneous skin changes after radiotherapy for breast cancer....
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0000000000001856
更新日期:2019-08-01 00:00:00
abstract::Despite many advances in reconstructive techniques, the full-thickness scalp defect remains a difficult problem for the reconstructive surgeon. Patient and disease-specific factors occasionally make reconstruction with a dermal regeneration template (DRT) an attractive option when other methods are less advised. Altho...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318243390b
更新日期:2012-05-01 00:00:00
abstract::After 30 years of clinical use, the 1992 Food and Drug Administration moratorium on silicone gel breast implants (SGBIs) resulted from a paucity of scientific data concerning their safety. The frequency of rupture and reoperative procedures was not known, nor were reliable data available for changes in the physical pr...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,meta分析
doi:10.1097/00000637-200209000-00001
更新日期:2002-09-01 00:00:00
abstract::The clavicular myocutaneous island flap, with circulation provided by the platysma and superficial cervical fascia, was first performed by Paul Tessier in 1970, taking his motivation from the prior experience of John Barron with subcutaneous island flaps. A manuscript written by Dr. Tessier on his experience of 120 ca...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0b013e3182183652
更新日期:2011-12-01 00:00:00
abstract::Prominent malar eminences are considered aesthetic and have been equated with a more youthful appearance. The precise area for accentuation and the surgical method for altering contour have not been universally agreed upon. A new technique for evaluation is suggested, and a surgical osteotomy for malar contouring is d...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198803000-00003
更新日期:1988-03-01 00:00:00
abstract::With a rise in tissue expander-based breast reconstructions (TEBRs) using acellular dermal matrix (ADM), we have seen an increase in ADM-specific complications. In this study, we aimed to evaluate clinically significant seroma (CSS) formation-defined by the need for a drainage procedure-to determine if there was a dif...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3182923dc9
更新日期:2013-09-01 00:00:00