Abstract:
:In a prospective phase II study 15 patients suffering from anaplastic thyroid carcinoma or thyroid sarcoma were treated by surgery and chemotherapy. Chemotherapy varied according to age of the patient and histological subtype of the tumour. The following regimen was used: 100 mg/m2 BSA CDDP, 20 mg/m2 mitoxantrone and 1.5 mg/m2 vincristine. 10 patients responded to chemotherapy, 4 of whom had a complete response. Responders showed a longer mean and median survival time (20.8 months versus 4.5 ms, 15.5 ms vs. 3.8 ms, respectively) than non-responders. In the group responding to chemotherapy no evidence of metachronous metastases was found. Local recurrence was absent only in the patients showing a complete response. Anaplastic carcinomas with areas of differentiated thyroid carcinoma and small cell carcinomas (after exclusion of malignant lymphoma of the thyroid) showed a higher response rate to chemotherapy than spindle or giant cell carcinoma or thyroid sarcoma.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Kober F,Heiss A,Keminger K,Depisch Dsubject
Has Abstractpub_date
1990-04-27 00:00:00pages
274-6issue
9eissn
0043-5325issn
1613-7671journal_volume
102pub_type
杂志文章abstract::Childhood IQ and adult morbidity and mortality are known to be linked even beyond socioeconomic variables. Yet, their interrelations are insufficiently understood. It has been suggested that bodily sensations play a fundamental role in health-related self-regulation and that intelligence can influence the information ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-010-1481-3
更新日期:2010-12-01 00:00:00
abstract:AIMS:Comorbidities pose a major challenge to screening, selection and follow-up of transcatheter aortic valve implantation (TAVI) patients as well as to the procedure itself. The aim of the present study was to assess cardiac and non-cardiac readmission rates besides clinical endpoint data in the first 50 patients of a...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-011-0075-z
更新日期:2012-01-01 00:00:00
abstract::Within the framework of an experimentally introduced curriculum in Medical Physiology during the past three years, voluntary tests of the multiple-choice type were offered at the end of each term in order to provide students with feedback on their achievements. Positive results contribute to the final grade. Analysis ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1979-07-13 00:00:00
abstract::The retrospective analysis of 672 consecutive patients with breast cancer revealed malignant pleural effusion and lymphangitic carcinomatosis of the lung to be the sites of first relapse of the disease in only 2% and 1%, respectively. In half of the 10 patients with malignant pleural effusions evaluable for survival, ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::1589 patients treated between 1965 and 1985 at the First Surgical Department of Vienna University were investigated to answer the following questions: 1. Development of postoperative mortality. 2. Is a palliative gastrectomy indicated? 3. Does gastrectomy en principe improve survival? 4. Quality of life after total ga...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-06-12 00:00:00
abstract::To evaluate the impact of the increase in consultation fees on malaria incidence in children presenting in the outpatient clinic of a privately funded hospital, we measured the impact of two fee increases on the number of pediatric outpatients. A 74% reduction in outpatients and a 78% reduction in malaria cases occurr...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/BF03040905
更新日期:2004-05-31 00:00:00
abstract::The results obtained by closest cooperation between gynaecologist and andrologist in the treatment of sterile marriages are reported. 127 couples were treated over a period of 20 months. Almost 100% of the males and 60% of the females were sub- or infertile. Treatment of both partners was meticulously coordinated in o...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1980-05-09 00:00:00
abstract:INTRODUCTION:Several variables of health-related human behaviour have been analysed with regard to a possible association with lunar phases. The aim of this study was to evaluate a possible relation between the lunar cycle and the number of requests for appointments at an outpatient clinic. This variable has not been s...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/BF03040335
更新日期:2003-05-15 00:00:00
abstract::Cholelithiasis is a rare, but important condition to be considered in the differential diagnosis of abdominal symptoms in childhood and adolescence. A survey over a 20-year period revealed 10 cases between the ages of 11 and 20 years, with a clinical history of cholelithiasis of between 5 days and 6 years. The most co...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1977-10-28 00:00:00
abstract::The case is reported of a patient in whom a granulosa cell tumour of the right ovary was removed at the age of 47 years. 14 years later the same type of tumour was found in the left ovary, together with an adenocarcinoma of the body of the uterus. 5 years after removal of these neoplasms splenectomy was carried out on...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1977-04-29 00:00:00
abstract::In myasthenia gravis respiratory function is often disturbed in the night, especially during REM sleep, despite of normal daytime respiratory function. Nevertheless, nocturnal respiratory problems are rarely diagnosed. Sleepiness, concentration and memory problems can be symptoms of a sleep related breathing disorder....
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:2001-04-17 00:00:00
abstract::The present study aimed at elucidating lytic effector cell function in 32 schizophrenic patients and comparing the results with data obtained in 27 normal probands. Natural killer cell (NK) activity and antibody dependent cellular cytotoxicity (ADCC) were tested. Schizophrenics did not differ from normal controls in e...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1988-06-10 00:00:00
abstract:BACKGROUND:Osteoarthritis (OA) of the hip is a frequent and debilitating joint disease. Only few clinical risk factors for hip OA are established and clinically applicable biomarkers to identify patients at risk are still lacking. The glycoprotein vascular cell adhesion molecule 1 (VCAM-1) is expressed by chondrocytes ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-019-1497-2
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To determine the proportion of children with an acute cough and laboratory evidence of Bordetella pertussis (B. pertussis) and B. parapertussis infection. METHODS:A prospective study was done, including children aged 0 months to 16 years who attended the outpatient clinic of the Innsbruck University Hospital...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2002-06-14 00:00:00
abstract::Surgical removal of enlarged parathyroid glands is the treatment of choice in most cases of tertiary renal hyperparathyroidism. Complications of this surgical procedure are rare. We report two cases of patients who developed acute hyperthyroidism after total parathyroidectomy with parathyroid autotransplantation for r...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-008-0996-3
更新日期:2008-01-01 00:00:00
abstract::Normalisation of intact parathyroid hormone serum level confirms sufficient resection of parathyroid tissue after total parathyroidectomy in patients with secondary hyperparathyroidism. The short half-life of the intact parathyroid hormone is such that complete resection may even be confirmed by intraoperative monitor...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1999-03-26 00:00:00
abstract::Stool samples from 523 children aged between 3 months and 6 years were examined for Cryptosporidium parvum by means of the direct immunofluorescence technique in March 1996. The specimens were sent to the Federal Public Health Laboratory in Innsbruck from general practitioners and pediatricians and from hospitals in T...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The case reports are presented of two siblings with familial thymoma. The thymomas developed at the same age in both siblings. The tumours were removed by thoracotomy and classified histologically as identical thymic squamous cell carcinomas. The brother is still alive and well four years after treatment; the sister d...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1983-06-10 00:00:00
abstract::Concomitant hydrocortisone and arginine vasopressin therapy increases arginine vasopressin plasma levels and may improve survival in septic shock. The objective of this post hoc analysis of a prospective study was to determine whether hydrocortisone therapy increases arginine vasopressin plasma levels in patients with...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-011-1568-5
更新日期:2011-04-01 00:00:00
abstract:AIM OF THE STUDY:To establish the prevalence of vertebral fractures according to age groups, sex and vertebral level in a sample of a Croatian urban population aged > or =50. We also tried to establish how many people had been diagnosed with osteoporosis by their family physician. PARTICIPANTS AND METHODS:Lateral thor...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00508-004-0292-9
更新日期:2005-01-01 00:00:00
abstract::In the introduction, the changes in the clinical features of tuberculosis over the past few decades are analyzed. Despite the reverse trend in incidence, tuberculosis is still one of the major infectious diseases in the world. The essential points in fighting tuberculosis are prophylaxis and early diagnosis, therapy h...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract:PURPOSE:Patients with localized prostate cancer are treated with 3D radiotherapy using a rectal balloon catheter for internal immobilization of the prostate, thereby reducing the radiation dose to the dorsal rectal wall. The purpose of the study was to investigate clinical feasibility and the influence of acute rectal ...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s00508-006-0588-z
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:The 6 min pegboard and ring test (6PBRT) is a valid and reproducible test of unsupported arm exercise endurance. The aim of this study was to determine the associations between the 6PBRT, activities of daily living (ADL) and hemoglobin levels in chronic obstructive pulmonary disease (COPD). METHODS:This stu...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-020-01635-8
更新日期:2020-03-25 00:00:00
abstract::As a result of progress in the modern treatment of burns, systemic candidosis (CA), in the sense of "surviving mycoses", has become increasingly frequent. The site of entry is not usually the wound, but the intestinal tract, which becomes overgrown by the yeasts as a consequence of the requisite therapy with antibacte...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-11-12 00:00:00
abstract::A report is given of 135 panendoscopic examinations in acute upper gastrointestinal bleeding. The importance of endoscopy is underlined by the high incidence of erosions and potential bleeding sources, since these lesions are not detected by radiological examination. Nor is it possible by means of X-rays to distinguis...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-10-15 00:00:00
abstract:BACKGROUND:The purpose of our study was to assess anal function in professional mountain bikers, as an increasing number of cycling enthusiasts report functional and morphological problems in the anal region. We tried to find out if constant saddle vibration suffered by professional cyclists could lead to defecation di...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-006-0741-8
更新日期:2007-01-01 00:00:00
abstract::In order to investigate the association of urinary excretion of sodium and potassium with blood pressure, 72 prepubertal healthy children between 8 and 9 years were investigated in a cross sectional study. We determined anthropometric data, diastolic (DBP), and systolic blood pressure (SBP) and urinary excretion of so...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Guideline adherence of general practitioners (GP) regarding treatment of chronic conditions shows room for improvement. Thus, concepts have to be designed to promote quality of care. The aim of the interventional study "Improvement of Quality by Benchmarking" was to assess whether quality can be improved by self-audit...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,多中心研究
doi:10.1007/s00508-016-1064-z
更新日期:2016-10-01 00:00:00
abstract::Various kinds of electric currents were examined with regard to their efficacy in the relief of pain when applied transdermally. The most suitable form of current was applied to 39 cases (who had been especially selected in a negative sense) suffering from intractable pain. About half were patients with malignant dise...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1977-02-10 00:00:00
abstract::Titres of blood-group isoagglutinins and the serum concentration of immunoglobulins M and G were investigated in 388 inmates (89.7% females) of an old-age home, ranging in age from 78 to 99 years [mean (+/- s) = 85.7 years +/- 4.1 years]. Concentrations of isoagglutinins were positively correlated to the concentration...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-07-19 00:00:00