Abstract：
:A study was conducted to evaluate the association between PCBs in residential indoor air and in the serum of older, long time residents of three upper Hudson River communities. Samples of indoor air and of serum were collected from 170 persons 55 to 74 years of age, and analyzed for PCBs using glass capillary gas chromatography. After adjusting for age, BMI, cigarette smoking, and Hudson River fish consumption with multiple linear regression analysis, the results indicated statistically significant associations between concentrations in indoor air and serum for PCB-28, a lightly chlorinated congener common in air that accumulates in serum, and PCB-105. Duration of exposure was an important factor, since among persons who had lived in their home for 39 years or more, 11 of the 12 most commonly detected congeners were significantly correlated, as was their sum (∑ PCB). Significant associations between indoor air and serum PCB concentrations also were more likely when collected in cooler months and if the two samples were collected within 20 d of each other. The study is among the first to indicate that PCB concentrations characteristic of residential indoor air are associated with a detectable increase in body burden.
journal_name
Chemospherejournal_title
Chemosphereauthors
Fitzgerald EF,Shrestha S,Palmer PM,Wilson LR,Belanger EE,Gomez MI,Cayo MR,Hwang SAdoi
10.1016/j.chemosphere.2011.06.027subject
Has Abstractpub_date
2011-09-01 00:00:00pages
225-31issue
2eissn
0045-6535issn
1879-1298pii
S0045-6535(11)00670-9journal_volume
85pub_type
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