Abstract:
:Organochlorines (polychlorinated biphenyls and dioxin-like compounds) are suspected to play a role in the etiopathogenesis of endometriosis. This hypothesis, based on experimental data, has been circulating for years in the scientific community and several epidemiologic surveys have attempted to obtain confirmatory human data. The purpose of this mini-review is to provide an overview of the twelve epidemiological studies that have assessed the relationship between endometriosis and organochlorine exposure. Several studies did not observe a significant association between peritoneal endometriosis and organochlorines. The deep nodular form of endometriosis appears associated with a higher serum level of both dioxin-like compounds and polychlorobiphenyls. The type of control women, the nature of the chemicals measured, and the definition of the disease could modulate the ability to detect the possible relationship between endometriosis and organochlorine exposure.
journal_name
Chemospherejournal_title
Chemosphereauthors
Heilier JF,Donnez J,Lison Ddoi
10.1016/j.chemosphere.2007.09.044subject
Has Abstractpub_date
2008-03-01 00:00:00pages
203-10issue
2eissn
0045-6535issn
1879-1298pii
S0045-6535(07)01218-0journal_volume
71pub_type
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