Grover disease: review of subtypes with a focus on management options.

Abstract:

:Grover disease (GD) is a benign eruption that causes a papulovesicular rash on the trunk and proximal extremities. It often resolves spontaneously but can follow a more chronic and fluctuating course that may last several years. Although the etiology remains unknown, several associated triggers have been identified including heat and sweating, cool and dry air, renal failure, malignancy, and the initiation of several drugs. Since the disease tends to resolve on its own, management is aimed at disease prevention and symptomatic relief. First-line therapy includes topical steroids and vitamin D analogues with adjuvant antihistamines. In more severe cases that are refractory to less aggressive therapy, systemic corticosteroids, retinoids, and phototherapy may lead to successful resolution. Novel therapies are few and have little evidence but involve innovative use of light therapy and immune modulators. Herein, we review the literature and new trends of GD with a focus on established and novel treatments.

journal_name

Int J Dermatol

authors

Aldana PC,Khachemoune A

doi

10.1111/ijd.14700

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

543-550

issue

5

eissn

0011-9059

issn

1365-4632

journal_volume

59

pub_type

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