["Does happiness help healing?" Immune response of hospitalized children may change during visits of the Smiling Hospital Foundation's Artists].

Abstract:

UNLABELLED:Psychoneuroimmunologic studies on positive emotions are few, and their clinical relevance is limited. AIMS:This "SHoRT" (Smiling Hospital Research Team) study evaluates the effects that Smiling Hospital artists have on hospitalized children. METHODS:Blood samples were taken in a non-painful way through branules in an accredited Infectology Ward, 30 minutes before and 1 hour after a visit of tale tellers, puppeteers and handicraft artists. 24 children were visited and 9 were included in the control group. Blood lymphocyte counts and Th1/Th2 cytokine levels were determined. Artists evaluated their effect on a subjective scale. RESULTS:In the visited group, the increase of lymphocytes was 8.43% higher, the decrease was 12.45% lower, and the proportion of children showing increased lymphocyte counts was more increased. Changes were more marked after more successful visits. Authors found non-significant, still considerable changes in interferon-γ level (p < 0.055) and in Th1/Th2 cytokine ratios. CONCLUSIONS:This pediatric study suggests that immunological changes may develop when more attention is given to hospitalized children.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Béres A,Lelovics Z,Antal P,Hajós G,Gézsi A,Czéh A,Lantos E,Major T

doi

10.1556/OH.2011.29228

subject

Has Abstract

pub_date

2011-10-23 00:00:00

pages

1739-44

issue

43

eissn

0030-6002

issn

1788-6120

pii

20Q7G1766256177X

journal_volume

152

pub_type

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