Abstract:
:The role of endothelium in vasodilatation has only emerged in the last ten years. It was observed that many endogenous substances from endothelial cells triggered the release of a substance which was named endothelium-derived relaxing factor (EDRF). Later has been showed that NO accounted for most if not all of the biological activity of EDRF. The endothelial synthesis of NO originates from L-arginine and could be blocked by the methyl analogue (e.g. NG-mono-methyl-L-arginine). Beside endothelial cells NO could be identified in several mammalian tissues including brain, hepatocytes, lung and macrophages. NO mediated the control of vascular tone and blood pressure via vascular smooth muscle cells which exert relaxation and constriction of blood vessels. It is considered NO represents signal for the guanylate cyclase system which regulates the intracellular concentration of Ca2+ ions. It is well known that the concentration of Ca2+ ions play discern direct role in the relaxation and contraction of smooth muscle, respectively.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Antoni F,Csuka I,Romics Lsubject
Has Abstractpub_date
1992-03-29 00:00:00pages
773-6issue
13eissn
0030-6002issn
1788-6120journal_volume
133pub_type
杂志文章,评审相关文献
ORVOSI HETILAP文献大全abstract:INTRODUCTION:It shows the importance of cerebrovascular diseases that they are the third main cause of death exceeded only by coronary artery diseases and cancer. Cerebral ischemia leads to irreversible brain damage, thereby it is important to rescue the hypoperfused areas. Patients without stroke but with chronic cere...
journal_title:Orvosi hetilap
pub_type: 杂志文章,meta分析
doi:10.1556/OH.2007.28115
更新日期:2007-07-22 00:00:00
abstract::Polymyositis-dermatomyositis is a rare systemic autoimmune disease which belongs to the class of idiopathic inflammatory myopathies. The disease exhibits high inter-individual variability, but chronic myositis is a common feature. As different manifestations often appear in atypical forms, establishing the precise dia...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2012.29300
更新日期:2012-03-25 00:00:00
abstract::The authors review the case of a 30 years old female patient presenting with a 48 hours-standing anuria, who permanently used products of grist of a virtuous plant, Guarana and occasionally used a parenteral non-steroid painkiller. The clinical history and laboratory results showed acute renal and hepatic failure. The...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2007.27954
更新日期:2007-03-04 00:00:00
abstract::Cardiovascular diseases are the main causes of premature death worldwide despite the fact that cardiovascular mortality decreased significantly in the last few decades in financially developed countries. This reduction is partly due to the modern medical and revascularisation treatments, and partly because of the effe...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2016.30577
更新日期:2016-09-01 00:00:00
abstract::Metabolic bone disorders have attracted increasing attention in Hungary due to their significant impact on public health care. Measuring urinary calcium excretion is the first step in the biochemical assessment of bone metabolism. Fasting urinary calcium corrected by creatinine excretion is widely used all over the wo...
journal_title:Orvosi hetilap
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1997-06-01 00:00:00
abstract::Interest in endoscopic ultrasonography (EUS) has increased during the past fifteen years. Since few years new instrument have been produced, which was equipped with a small curved array transducer mounted in a front of the optic lens. The instrument, which is connected to a Hitachi ultrasonic scanner allows for duplex...
journal_title:Orvosi hetilap
pub_type: 临床试验,杂志文章
doi:
更新日期:1997-01-12 00:00:00
abstract::Non alcoholic fatty liver disease is the hepatic manifestation of metabolic syndrome, and the most common liver disease. Its more aggressive form is the non alcoholic steatohepatitis. Multiple genetic and environmental factors lead to the accumulation of triglicerides and the inflammatory cascade. High fat diet, obesi...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2017.30775
更新日期:2017-06-01 00:00:00
abstract::The results of 1122 laparoscopic cholecystectomies have been analyzed which were performed within a two year period of time. In 1097 (97.8%) cases the authors managed to carry out the laparoscopic procedure, however in 25 patients (2.2%) the operation had to be converted to an open surgery. There was no hospital morta...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-24 00:00:00
abstract::Around 25% of medullary thyroid carcinoma (MTC) cases are familial and follow an autosomal dominant mode of inheritance. In these cases, MTC is part of an inherited cancer syndrome that has three distinct forms: MEN2A, MEN2B and familial MTC (FMTC). MEN2A is the most frequent syndrome, followed by FMTC and MEN2B. In 9...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1999-12-05 00:00:00
abstract::The author calls the attention, with reference to the four cases observed lately, to the reappearence of the Volkmann's ischaemic contracture, which was described at the end of the 19th century, but has been almost forgotten with the developing of traumatology. It discusses the reasons of development, the results and ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2009.28515
更新日期:2009-01-04 00:00:00
abstract::The surgical management of congenital heart defects is changing continuously due to technical development. Aortic coarctation is one of the most frequent congenital heart diseases often with serious symptoms. The authors review the different surgical techniques (end-to-end anastomosis, pathplasty, interposition) and p...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2020.31730
更新日期:2020-05-01 00:00:00
abstract::Authors describe two cases of lead poisoning of unusual origin. A 43 year old male patient bought some waste metal in order to build a fence around his new house for saving money. He removed the old corroded coat of paint using a grinder without any protection. Consequently, he had got grave lead intoxication with col...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1997-11-02 00:00:00
abstract::The authors present the case history of a 2 year old child suffering from nesidioblastosis. Severe non-ketotic symptomatic hypoglycaemia developed within the first hour of birth. Diagnosis of nesidioblastosis was confirmed by high insulin concentration accompanying hypoglycaemia, the increase in blood glucose level af...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-07-23 00:00:00
abstract:INTRODUCTION:Oxidative-nitrative stress and poly(ADP-ribose) polymerase activation observed in gestational diabetes may play role in the increased cardiovascular risk in later life. AIM:The present study aimed to examine the influence of the severity of previous gestational diabetes (insulin need) on vascular function...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2015.30307
更新日期:2015-11-22 00:00:00
abstract::The authors detected Epstein-Barr virus (EBV) virus capsid (VCA) antibodies of IgM and IgG type together with EBNA and heterophil antibodies in the sera collected from 1882 unselected patients without infectious mononucleosis. Out of them IgM type antibodies were found in 123 cases and in an additional group of 30 pat...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1996-07-28 00:00:00
abstract::The advances in molecular genetic methods has lead to the discovery of the genetic alterations that underlie the etiology of most diseases previously held to be idiopathic. Targeted genetic examination of a pediatric male patient showing a normal intellect, an extended area of skin hypopigmentation, and suffering from...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2019.31404
更新日期:2019-05-01 00:00:00
abstract::The literature of breast-screening is vastly large, and enlarges by newer publications permanently. This summary can only be confined to publish data, with arbitrary selection. The mass-screening of complaintless and symptomless persons for early recognition of certain illnesses is to be completed according to distric...
journal_title:Orvosi hetilap
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:2003-02-16 00:00:00
abstract::HHV-6A in vitro augments expression of CD4 molecules on the surface of immune cells, facilitates HIV replication and cell death in dual infections. It is hardly known whether these processes take place in vivo; does HHV-6A enhance HIV infection and AIDS progression? To study HHV-6A fresh infections and reactivation, I...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1999-08-22 00:00:00
abstract::A case of eosinophilic gastritis is reported in a 65-year-old woman. The disease presented with signs of delayed emptying, vomiting and substantial thickening of the antrum. Partial gastrectomy was performed because of the suspicion of gastric cancer and pyloric stenosis. Histopathology established the diagnosis of eo...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2003-03-16 00:00:00
abstract:UNLABELLED:Transplant patients' attitudes and representations related to their illness, their body, and the healing process have a significant impact on their recovery. AIMS:The study involved 51 patients from the Department of Surgery, University of Szeged, Hungary. The primary aim was to examine the possible connect...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2012.29327
更新日期:2012-04-15 00:00:00
abstract:INTRODUCTION:Abnormal sensations such as pain and impairment of taste are symptoms of approximately 10% of patients having diabetes mellitus. AIM:The aim of the study was to investigate and quantify the different neuropeptide containing nerve fibres in the vallate papilla of the diabetic rat. METHODS:Immunohistochemi...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2013.29570
更新日期:2013-03-24 00:00:00
abstract::In nonselected patients 81.5% stone-free rate could be reached in 3 months. In authors's opinion Direx Tripter X-1 is suitable in the treatment of renal and ureteral calculi. They treated staghorn calculi by ESWL monotherapy with success. The Direx lithotripter was found to be effective and easy to operate; the potent...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1992-08-16 00:00:00
abstract:INTRODUCTION:Congenital heart defects are frequently present in patients with Down syndrome. AIM:The authors analyzed the impact of changing approach in surgical management of congenital heart defect on the life expectancy of patients with Down syndrome. METHOD:Between 1974 and 1997 the data of 359 children with Down...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2016.30529
更新日期:2016-10-01 00:00:00
abstract::Treatment of thoracoabdominal aortic aneurysms is one of the most difficult challenges of vascular surgery. Endovascular options for complex aneurysms in urgent situation are limited. Thoracoabdominal giant aortic aneurysms are especially rare phenomena, each of them requires patient-specific treatment. Staged-fashion...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31676
更新日期:2020-02-01 00:00:00
abstract::Major trauma is a frequent cause of death, and is the leading cause of death in the younger agegroups. Severe bleeding is often responsible for early mortality. The background of the latter is the trauma-induced coagulopathy (TIC), which - often very early - develops after the onset of bleeding. The high amount of blo...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31885
更新日期:2020-09-01 00:00:00
abstract::The authors discuss the role of nuclear medicine techniques in the modern diagnostics of breast cancer, including the methods currently used in Hungary and the future possibilities. ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2012.29256
更新日期:2012-01-08 00:00:00
abstract::A large number of studies have demonstrated the long term disadvantage of single lead ventricular pacing in sick sinus syndrome. Ventricular pacing mode predicts chronic atrial fibrillation in patients with preimplant paroxysmal atrial fibrillation. The goal of the report was to study the effectiveness of single atria...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1999-10-24 00:00:00
abstract::The author summarizes the most effective types of glaucoma surgery in advanced glaucoma. In high pressure advanced glaucoma a low target intraocular pressure is to be set. The most effective method of reaching this target pressure level is mitomycin C trabeculectomy combined with effective pre- and postoperative antii...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2013.29801
更新日期:2013-12-29 00:00:00
abstract::Inflammatory disorders of the thyroid gland are divided into three groups according to their duration (acute, subacute and chronic). De Quervain's thyroiditis (also termed giant cell or granulomatous thyroiditis) is a subacute inflammation of the thyroid, which accounts for 5% of thyroid disorders. The etiology is unk...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2014.29865
更新日期:2014-04-27 00:00:00
abstract:INTRODUCTION:Examination of the gut-liver axis came into the spotlight worldwide. Liver enzyme elevations are commonly seen in patients with inflammatory bowel disease (IBD), which is a diagnostic challenge in everyday clinical practice. Liver and biliary diseases are common extra-intestinal manifestations in Crohn's d...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2017.30781
更新日期:2017-07-01 00:00:00