[Polymyositis-dermatomyositis recognized during the follow-up of a patient with type 2 diabetes].

Abstract:

:Polymyositis-dermatomyositis is a rare systemic autoimmune disease which belongs to the class of idiopathic inflammatory myopathies. The disease exhibits high inter-individual variability, but chronic myositis is a common feature. As different manifestations often appear in atypical forms, establishing the precise diagnosis can be rather complicated. The prognosis and the patient's life expectations highly depend on whether the clinician considers this possibility in the diagnostic process or not. The authors present the case of a 50-year-old woman who was referred to hospital with suspected myopathy by her general practitioner. The history of the patient, the overall clinical picture and some marked laboratory abnormalities raised the possibility of polymyositis-dermatomyositis, which was unequivocally confirmed by immunological tests. Drug therapy was started immediately with the administration of high dose corticosteroid (1-2 mg/kg/day methylprednisolone), which was found to be an effective strategy leading to fast and remarkable improvement in the patient's condition. From the first hospital day, the patient also received insulin therapy in order to prevent any potential corticosteroid-induced imbalance in her carbohydrate metabolism. The long-term patient management was provided by an interdisciplinary team the members of which (both clinicians and other health care professionals) worked according to a co-ordinated, complex care plan, and managed not only the "physiological functions" but the different psychological and social problems as well, which are usually associated with the disease. The follow-up period of this polyphase disease process lasted for 4.5 years, during which only two relapses occurred, and muscle strength typically varied between 3 and 4 on a five grade scale with the exception of the relapse periods. Good outcome was attributed to the strict follow-up and individualized therapy/care.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Samer F,Csóka M,Dankó K

doi

10.1556/OH.2012.29300

subject

Has Abstract

pub_date

2012-03-25 00:00:00

pages

467-74

issue

12

eissn

0030-6002

issn

1788-6120

pii

1777331537Q88U32

journal_volume

153

pub_type

杂志文章
  • [Hans Selye, the grandmaster of creativity and originality].

    abstract::Hans Selye, the father of the stress concept, was a giant of science of the twentieth century. Beyond his best-known work on stress, he also made several discoveries on various other fields of experimental medicine. He described and characterized various pluricausal diseases. In addition, he made pivotal contributions...

    journal_title:Orvosi hetilap

    pub_type: 传,历史文章,杂志文章

    doi:10.1556/650.2015.30245

    authors: Somogyi Á

    更新日期:2015-08-30 00:00:00

  • [Polymerase chain reaction and its application].

    abstract::The polymerase chain reaction (PCR) is one of the most important new methods in molecular biology. It is widely used in genetic and anthropologic basic research, in oncology and virology, in all those fields, where molecular biologic methods can give answers to the questions raised. The procedure enables one to multip...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Sárosi I,Gerald E,Girish VN

    更新日期:1992-07-05 00:00:00

  • [Leiomyosarcoma in the male breast].

    abstract::Leiomyosarcoma of a 61 y.o. male's breast was removed by the authors. This observation is the first in the Hungarian and third in the world literature. Short survey is taken of the aetiology, prognosis and therapeutic possibilities of male breast cancers. ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Farkas E,Köves I,Besznyák I,Sápi Z,Sulyok Z

    更新日期:1991-07-07 00:00:00

  • [Vascular endothelial dysfunction, oxidative stress--a new topic within the referral section of Orvosi Hetilap].

    abstract::The author describes some of the numerous domains regarding the new topic called "Vascular endothelial dysfunction, oxidative stress". The endothelium is responsible for the constancy and integrity of the milieu interieur by producing various substances. Endothelial dysfunction occurs when there is imbalance between v...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2008.28402

    authors: Fischer T

    更新日期:2008-07-13 00:00:00

  • [Public health control of hyperhomocysteinemia and its consequences].

    abstract::The etiological role of hyperhomocysteinemia in the origin of neural-tube defects was proved, therefore a mandatory flour folic acid fortification program was introduced in the USA since January 1, 1998. In Hungary one kind of breads was fortified with folic acid, vitamin B12 and vitamin B6. The Hungarian randomised c...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Czeizel E,Kalina A

    更新日期:2003-10-05 00:00:00

  • [Micturition syncope].

    abstract::The micturition syncope is a special manifestation of the so called "situational syncopes". These reflex syncopes share efferent mechanisms with the neurocardiogenic, or vasovagal syncope. A case of a patient is reported, who presented with micturition syncope. The patient's tendency for vasovagal syncope was document...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Rudas L,Kardos A,Halmai L,Török T,Pap I

    更新日期:1996-12-08 00:00:00

  • [Perioperative management of patients with Parkinson's disease. Review of the literature].

    abstract::Similarly to an increase in life expectancy, the incidence of Parkinson's disease increases as well. In parallel with this, more patients with Parkinson's disease undergo elective or urgent surgical interventions. According to recent statistical data, more than half of the patients with Parkinson's disease are not pro...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/650.2015.30233

    authors: Fülesdi B,Mitre C,Molnár C

    更新日期:2015-08-23 00:00:00

  • [The future of pathology--from the viewpoint of clinical pathology].

    abstract::Pathology is one of the fundamental diagnostic fields of medicine, its position has changed and will undergo transformation in the 21st century due to the introduction of new methods. Theoretically, pathology was based upon 3 pillars: 1. the autopsies, 2. the surgical pathology, i.e. the processing and evaluation of d...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Bajtai A,Nemesánszky E

    更新日期:2002-04-28 00:00:00

  • [Immune responses of IgG, IgA and anti-CagA IgG to Helicobacter pylori in dyspeptic and peptic ulcer patients].

    abstract::The anti-H. pylori IgG, IgA, and anti CagA responses in dyspeptic patients have been evaluated. Of 481 patients 76% tested positive for IgG anti-H. pylori, 57% for anti-CagA, and 52% IgA for anti H. pylori. There was a significant age-related increase in IgG anti-H. pylori and IgA anti-H. Pylori prevalence, whereas an...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Tamássy K,Auli P,Fekete B,Antonello C

    更新日期:1997-04-20 00:00:00

  • [H2-receptor antagonists and alcohol: clinical significance].

    abstract::The aim of the review is to evaluate the putative clinical interactions between alcohol metabolism and the administration of H2-receptor antagonists. Places of the first-pass metabolism of ethanol in the body have been investigated as well. According to the in vitro experimental results the H2-receptor antagonists can...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Nemesánszky E,Csepregi A

    更新日期:1996-06-16 00:00:00

  • [SPECT--single photon emission computer tomography. A new imaging method in isotope diagnosis].

    abstract::The paper gives an introduction to the basis and quality control of a relatively new imaging method. First the different kinds of SPECT instruments, and then the aspects of diagnostic application are described. Details are given on examinations of the central nervous system, the abdomen, the hearth and the skeletal sy...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Csernay L

    更新日期:1989-03-19 00:00:00

  • [Clinical pharmacological aspects of the proton pump inhibitor therapy: importance of pharmacogenetic differences in the clinical practice].

    abstract::Proton pump inhibitors (PPIs) are widely used for the treatment of gastroesophageal reflux disease, as well as other acid-related disorders. Omeprazole, lansoprazole, pantoprazole, rabeprazole and esomeprazole effectively suppress gastric acid secretion by blocking the gastric acid pump, H+/K+ -adenosine triphosphatas...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2007.27902

    authors: Mullner K,Molnar B,Tulassay Z

    更新日期:2007-03-25 00:00:00

  • [Optical biopsy of the retina in vivo: on optical coherence tomography and its clinical use in ophthalmology].

    abstract::Optical Coherence Tomography (OCT) is a novel, non invasive imaging method, which enables in vivo assessment of living tissues, providing near histological resolution images. The first description of its clinical introduction was in ophthalmology, which substantially changed our view of specific retinal diseases. OCT ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Somfai GM,Salacz G

    更新日期:2005-05-22 00:00:00

  • [The role of computed tomography perfusion in the diagnosis of brain ischaemic stroke].

    abstract:UNLABELLED:In recent years, the broad introduction of fast multidetector computed tomography (CT) systems and the availability of commercial software for perfusion analysis have made cerebral perfusion imaging with CT a practical technique for the clinical environment. AIM AND METHODS:This article reviews the use of C...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2008.28323

    authors: Halász S,Puskás T

    更新日期:2008-06-08 00:00:00

  • [Comparison of SCORE and Reynolds cardiovascular risk assessments in a cohort without cardiovascular disease].

    abstract:INTRODUCTION:Cardiovascular risk assessment may help in the identification of symptom-free subjects with high cardiovascular risk. AIM:The author studied the correlation between SCORE and Reynolds risk assessment systems based on data from the cardiovascular risk screening program carried out in subjects without cardi...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2013.29730

    authors: Móczár C

    更新日期:2013-10-27 00:00:00

  • [Gastric and duodenal intramural hematoma: report of two cases].

    abstract::Two cases of intramural hematoma arising in the duodenum and the stomach are reported. Both patients were male, aged 40 and 58 years, and suffered from chronic pancreatitis. Hematoma of the duodenal wall may have resulted from the acute exacerbation of the chronic pancreatitis in the first patient. As to the second ca...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Dibuz M,Szabó T,Monoki E,Nagymélykuti L,Illyés M,Varga E,Csípö L

    更新日期:1998-12-06 00:00:00

  • [Hormonal and biochemical characterization of breast cyst fluid in gross cystic mastopathy].

    abstract::A total of 93 breast cyst fluids (BCF) obtained by needle aspiration of women suffering from gross cystic mastopathy was hormonally investigated. The mean age of the patients was 45 years (range 27-65). Estradiol (E2), progesterone (PROG), testosterone (TE), prolactin (PROL), estriol (E3), dehydroisoandrosterone and i...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Számel I,Budai B,Daubner K,Kralovánszky J,Csetényi J,Otto S,Besznyák I

    更新日期:1994-04-24 00:00:00

  • [Influence of diabetes mellitus on cerebral ischemia and reperfusion injury].

    abstract::Cerebral ischemia, caused by disturbance of the blood supply to the brain, is a major cause of death in our days. Diabetes mellitus exacerbates neuronal death induced by an ischemic insult. It is important to characterize the underlying mechanism of the cell damage in order to design therapeutic agents. The purpose of...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Murányi M,Lacza Z

    更新日期:2006-10-01 00:00:00

  • Incidence of haematological malignancies in adults in Szabolcs-Szatmár-Bereg county, Hungary. Analysis of data of a 36-year period

    abstract:INTRODUCTION:During a 36-year period (between January 1, 1983 and December 31, 2018), 5159 adult patients with newly diagnosed haematological malignancy were registered in the leukaemia/lymphoma registry of Szabolcs-Szatmár-Bereg county. AIM:The review of the incidence of different haematological malignancy in the aut...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/650.2020.31750

    authors: Jakó J,Takács P,Szerafin L

    更新日期:2020-08-01 00:00:00

  • [Acute renal failure caused by plant extract].

    abstract::The authors review the case of a 30 years old female patient presenting with a 48 hours-standing anuria, who permanently used products of grist of a virtuous plant, Guarana and occasionally used a parenteral non-steroid painkiller. The clinical history and laboratory results showed acute renal and hepatic failure. The...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2007.27954

    authors: Vágási K,Degrell P,Késoi I,Kovács T,Pintér I,Molnár B,Cseh J,Nagy J,Wittmann I

    更新日期:2007-03-04 00:00:00

  • [Facilitating the diagnosis of depression and burnout by identifying demographic and work-related risk and protective factors among nurses].

    abstract:INTRODUCTION:Depression and burnout are frequent comorbidities among nurses. Despite similar symptoms, their management differ. Therefore, their timely diagnosis is essential. AIM:To identify demographic and work-related risk and protective factors of burnout and depression, and facilitate their diagnosis. METHOD:A c...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/650.2015.30220

    authors: Ádám S,Nistor A,Nistor K,Cserháti Z,Mészáros V

    更新日期:2015-08-09 00:00:00

  • [Inclusion body myositis pathomechanism and therapy].

    abstract::Inclusion body myositis is an acquired inflammatory muscle disease belonging to the family of idiopathic inflammatory myopathy with vacuole formation. Approximately 15-28% of idiopathic inflammatory myopathy patients suffer from inclusion body myositis. Early diagnosis is very important due to the slowly progressive d...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2008.28070

    authors: Váncsa A,Dankó K

    更新日期:2008-07-27 00:00:00

  • [The cumulative risk index in stroke prevention].

    abstract::The screening and special management of high risk patient, is possible strategy to reduce the high morbidity and mortality of stroke. In the II. district of Budapest we examined high vascular risk patients cooperating with general practitioners. We let the severity of risk with arithmetic of the cumulative risk index....

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Szilágyi G,Szamosi T,Sárai A,Szemerédi P,Nagy Z

    更新日期:2000-04-23 00:00:00

  • [Potentials of interventional radiology: percutaneous radiofrequency ablation].

    abstract::The efficacy of the treatment of hepatic malignancies has improved, mostly due to the physical procedures which affect the tumors locally. The authors performed 210 radio-frequency ablations in 1.38 patients. They recommend this procedure based on their experiences. RF treatment is performed together with other therap...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Péter M,Tóth J

    更新日期:2004-02-15 00:00:00

  • [Possibilities of postnatal diagnosis in congenital cytomegalovirus infection].

    abstract::The authors review two cases of suspected congenital cytomegalovirus (CMV) infections in which modern laboratory approaches were applied to establish the diagnosis postnatally. In the first case, intrauterine infection was suggested by ventriculomegaly, detected by means of a head ultrasonographic scan. The postnatal ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Tokodi I,Pusztai R,Deák J,Kátai A,Kovács I,Simon G

    更新日期:2004-04-25 00:00:00

  • [A new thrombocyte aggregation-inhibiting and fibrinolysis-promoting synthetic molecule: RGDF (Arg-Gly-Asp-Phe) coupled with the carboxyterminal antiplasmin peptide].

    abstract:OBJECTIVE:Synthesize such hybrid peptides, which contain the RGD (Arg-Gly-Asp) sequence coupled with another peptide containing lysine residues in special positions, to inhibit simultaneously platelet activation and promote fibrinolytic processes. DESIGN:The in vitro haemostasis modifying properties of the synthesized...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Udrardy M,Schwartzott D,Jackson K,McKee PA

    更新日期:1995-01-15 00:00:00

  • [Epilepsy surgery in childhood: theory and practice].

    abstract::1-1.5% of the Hungarian child population has epilepsy, and around 20% of them produces seizures in spite of modern antiepileptic drugs. A part of the pharmaco-resistant children may benefit from surgical removal of the epileptogenic focus. Presurgical evaluation has been developed a lot since the progress of neuroimag...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Fogarasi A,Neuwirth M,Gyorsok Z,Czirják S,Vajda J,Bognár L

    更新日期:2003-11-30 00:00:00

  • [Subtotal petrosectomy - indications, surgical technique, experiences in Pécs].

    abstract::Introduction: Subtotal petrosectomy (STP) has been known for decades and it is considered being on the borderline between ear and skull-base surgery. Due to its excessive radicalism and adverse effects on hearing, it has been a forgotten surgical technique until recently. Over the last decade, due to its many benefits...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/650.2020.31691

    authors: Gerlinger I,Molnár K,Nepp N,Tóth I,Tóth T,Szanyi I,Bakó P,Pap I

    更新日期:2020-04-01 00:00:00

  • [Epidermoid cyst of the cecum].

    abstract::This paper describes a case of an epidermoid cyst arising in the anterior wall of the coecum. Epidermoid and dermoid cysts of the coecum are exceptionally rare. These cysts arise by the sequestration of squamous epithelium during embryological development, or following trauma or surgery. The true cysts are the result ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Vajda K,Drabos E

    更新日期:2001-07-22 00:00:00

  • [The value of detecting eosinophil cationic protein in various dermatoses].

    abstract::Recent data have proved that eosinophil cells actively contribute to the pathogenesis of numerous inflammations, including that of atopic dermatitis. The expression of the activated secreted forms of eosinophil cationic protein (ECP) as well as the determination of the rise and fluctuation of the ECP level of the seru...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Schneider I,Magyarlaki M,Tóth K

    更新日期:1994-10-30 00:00:00