Abstract:
BACKGROUND:Attention deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurobiological disorder of childhood onset, characterized by hyperactivity, impulsiveness or inattentiveness. AIM:To search for differences in risk for ADHD and its components among Chilean native and mixed populations and to look forpossible associations with dopamine receptor D4 (DRD4) and dopamine transporter 1 (DAT1) polymorphisms. MATERIAL AND METHODS:School teachers were requested to complete the Conners test, which uses DSM-IV criteria, to screen for ADHD risk among Aymara and Rapa-Nui students. RESULTS:Rapa-Nui children from Easter Island had the highest risk of hyperactivity/impulsiveness. Aymara children from the Arica-Parinacota Region had lower scores. Although inattentiveness scores had lower differences between groups, overall ADHD score differences among studied populations were highly significant. DRD4 and DAT1 alleles had a heterogeneous distribution. Easter islanders had more divergent frequencies, mostprobably as a result of separate migration routes utilized at different timeperiods during the colonization of America and Polynesia. CONCLUSIONS:The comparison of ADHD risk parameters between Rapa-Nui and Aymara children showed marked differences. Allele distri-bution of dopamine polymorphisms in Easter Island was also significantly different from northern Chile, due probably to different colonization histories. These findings suggest that higher ADHD risk scores in Easter Island children may be linked to the presence of different DRD4 alleles.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Paz Lagos L,Silva C,Rothhammer P,Carrasco X,Llop E,Aboitiz F,Rothhammer Fdoi
/S0034-98872011000500006subject
Has Abstractpub_date
2011-05-01 00:00:00pages
600-5issue
5eissn
0034-9887issn
0717-6163pii
S0034-98872011000500006journal_volume
139pub_type
杂志文章abstract::Acute coronary syndromes without ST segment elevation (Non-Q-Infarction and unstable angina) share a common pathophysiology, have no indication of thrombolysis, and should not routinely be catheterized on an emergency basis on admission. They should be put in bed rest, given anti-ischemic medications, aspirin and hepa...
journal_title:Revista medica de Chile
pub_type: 评论,社论
doi:
更新日期:1998-11-01 00:00:00
abstract::High blood pressure of unknown etiology has been related to many pathogenetic factors, mainly dietary salt intake, mental stress, alcohol consumption, sedentary living and aging. Hypertension is more common in condition such as obesity and diabetes mellitus. Sustained elevation of arterial pressure is mediated by vaso...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND:The easy access and inappropriate use of antimicrobials led to selection and spread of resistant microorganisms strains. It is imperative to search for new and more effective antimicrobials. One strategy is the screening of metabolites produced by microorganisms found in the environment. Actinomycetes are a ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872004000200003
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Pharmacological treatment improves survival in patients with heart failure with reduced ejection fraction. The use of sacubutril/valsartan and ivabradine has been recently approved and incorporated in the latest guidelines. AIM:To identify candidates eligible for these therapies among patients treated in a ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000300330
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Teaching practice is one of the most complex topics of the training process in medicine and other health care careers. The Teaching Practices Questionnaire (TPQ) evaluates teaching skills. AIM:To assess the factor structure and internal consistency of the Spanish version of the TPP among health care teacher...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872016000600015
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Intensive medicine is especially expensive and requires an efficient management. AIM:To measure the real costs of diseases treated in an intensive care unit and compare them with the costs assigned by the Chilean National Health Fund (FONASA) for 2008. MATERIAL AND METHODS:Retrospective review of 225 patie...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010000500005
更新日期:2010-05-01 00:00:00
abstract:UNLABELLED:Lack of social support can be one of the factors that influences recurrences of drug consumption after treatment of addictions. AIM:To assess the role of social support in maintaining drug abstinence after treatment. MATERIAL AND METHODS:We studied 306 subjects that were treated in drug addiction centers, ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,多中心研究
doi:/S0034-98872008000200005
更新日期:2008-02-01 00:00:00
abstract::DSM-5 is a significant factor in promoting the "remedicalization" of psychiatry as the focus of psychiatric knowledge, developed by the evidence-based medicine movement, shifted from the clinically-based biopsychosocial model to a research-based medical model. DSM-5 purposes are 1]clinical: diagnosis, prevention, earl...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000400475
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Psychological problems are a frequent cause of consultation in primary care outpatient clinics. AIM:To report the results for Santiago de Chile of the World Health Organisation multicentric collaborative study on Psychological Symptoms in General Health Care. PATIENTS AND METHODS:The results of 1453 patien...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:New vaccination strategies are needed to control the increasing problem of pertussis in teenagers and adults. AIM:To determine the immunogenicity and reactogenicity of a diphtheria-tetanus-acellular pertussis (dTpa) vaccine with reduced antigen content. MATERIAL AND METHODS:A single dose of the dTpa vaccin...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2002-05-01 00:00:00
abstract::Glucose toxicity refers to the structural and functional damage in the beta cells and target tissues of insulin, caused by chronic hyperglycemia. These alterations cause a lower hormonal secretion and action (insulin resistance). Lipid toxicity refers to the damage caused by persistently high free fatty acid levels, a...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:Squamous Cell Carcinoma (SCC) of the lip represents about 20% of all oral carcinomas. It is more common in men, peaking during their sixth and seventh decade, and is more prevalent in the lower lip. AIM:To determine the five years survival rate of Chilean patients with lip SCC. MATERIAL AND METHODS:The reg...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872015000700004
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:In Chile, leukemia is one of the diseases whose treatment is guaranteed by a special law called AUGE (universal access and explicit guaranties). Therefore, the knowledge of its treatment costs is of utmost importance. AIM:To determine and to characterize the direct costs of pharmacotherapy for leukemia at a...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009001200002
更新日期:2009-12-01 00:00:00
abstract:UNLABELLED:Appropriate antimicrobial therapy shortens the duration of Shigellosis and significantly reduces the risk of transmission. Shigella strains resistant to common antimicrobials have increased during the past years, determining the need for a periodic surveillance, to guide effective therapy. AIM:To report the...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract::The preliminary results of a prospective and cooperative protocol for the treatment of soft tissue sarcomas of trunk and extremities, stages IB-IIIB are presented. Thirty one patients (17 males, 22 with a tumor larger than 5 cm) aged 16 to 68 years, were treated with one dose of epirubicin 70 mg/m2 i.v. and radiothera...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::Brain functioning is mainly intrinsic, not primarily reflexive. This is supported by the high energy requirements of the resting brain (20% of all the energy consumed) which only marginally increases with changes in brain activity. Modern neuroimaging and neurophysiological techniques have led to the discovery of the ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872013000300014
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Depression is considered the second leading cause of disability worldwide. AIM:To describe the clinical characteristics and the evolution of major depressive disorder (MDD) in secondary care. To evaluate the association between socio-demographic and clinic variables with the first or recurrent major depress...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000300007
更新日期:2017-03-01 00:00:00
abstract::To adequately plan the post graduate training of physicians, we need to know the needs for specialists in the country and the most prevalent diseases and causes of consultations. In 2004, the National System of Health Services assessed the number of hours and types of specialties available, their regional distribution...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008000100013
更新日期:2008-01-01 00:00:00
abstract::Splenic abscesses are infrequent and usually associated to sepsis and immunodepression. The diagnosis is commonly made in the necropsy. We report two cases of multiple splenic abscesses in type II diabetic patients that were diagnosed by ultrasound. Both patients were successfully managed with surgery (drainage of lef...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
abstract::The new Chilean regulation about patients' rights and duties is generating a significant change in the information that health care professionals must provide to their patients. This issue will gravitate on medical liability. If this duty is accomplished incorrectly, professionals would fall into an illicit act and be...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000800909
更新日期:2018-08-01 00:00:00
abstract::Background The treatment of choice of newly diagnosed multiple myeloma (NDMM) is an induction with proteasome inhibitors followed autologous stem cell transplantation (HSCT). Since 2013, the treatment of these patients in the public system is based on CTD (cyclophosphamide, thalidomide, and dexamethasone). Aim To eval...
journal_title:Revista medica de Chile
pub_type: 杂志文章,多中心研究
doi:10.4067/S0034-98872019001201561
更新日期:2019-12-01 00:00:00
abstract::Hospital bed availability, trends in number of beds, productivity and administrative aspects in the public and private hospital sectors are analyzed. At present, there are 3.3 beds per 1000 population in Chile. This represents a decrease from previous figures, in spite of increasing demands derived from population agi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND:The incidence of morbid obesity is increasing and gastric bypass is the most effective surgical treatment. AIM:To assess the long term results of resection gastric bypass among morbidly obese patients aged less than 18 and over 65 years in terms of weight loss and correction comorbidities. MATERIAL AND MET...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008001000003
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Cardiac rehabilitation (CR) programs play an important role in the control and prevention of new cardiac events. AIM:A survey was performed to evaluate the current situation of CR programs in Chile. MATERIAL AND METHODS:A questionnaire evaluating the structure of rehabilitation centers, characteristics of ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000500002
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:the six minute walking distance test (6MWD) is widely used to evaluate exercise capacity in several diseases due to its simplicity and low cost. AIM:to establish reference values for 6MWD in healthy Chilean individuals. MATERIAL AND METHODS:we studied 175 healthy volunteers aged 20-80 years (98 women) with...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010000900006
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Self-efficacy refers to people's expectations about personal resources available for goal achievement. Higher self-efficacy expectations are correlated with higher academic performance. AIM:To analyze the psychometric properties of the Academic Behavior Self-Efficacy Scale (ABSES) and to describe Self-effic...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000700914
更新日期:2019-07-01 00:00:00
abstract::Recent reports have described a pathogenic role of nitric oxide in several respiratory disease. It is specially useful in the adult respiratory distress syndrome, where it acts as a selective vasodilator and improves gas exchange, decreasing pulmonary shunting. Although it has a proven bronchodilator effect, its thera...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1997-08-01 00:00:00
abstract::The aim of this study was to assess the predictive value for mortality of admission and daily APACHE II score, mortality due to multiple organ failure and the Organ Failure Score in patients with acute hepatic failure. We retrospectively studied 15 such patients admitted to an intensive care unit. Thirteen patients di...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:The Chilean Ministry of Health has been using standards for nutritional evaluation and weight gain recommendations during pregnancy in the last 25 years. In the meantime new standards have been developed. AIM:To study the combined influence of preconception maternal nutritional status and gestational weight...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000600003
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Oral cancer in Chile corresponds approximately to 1.6% of all cancer cases. There are few studies about oral epithelial dysplasia and oral squamous cell carcinoma in the Chilean population. AIM:To determine the frequency of hyperkeratosis, mild, moderate and severe oral epithelial dysplasia, in situ carcino...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872016000200004
更新日期:2016-02-01 00:00:00