Abstract:
:A 29-year-old man presented with abdominal cramps and bloody diarrhoea. Blood tests revealed elevated C-reactive protein (21.3 mg/dL; normal range 0.01 - 0. 82 mg/dL) and white blood cells (28200/μL, normal range 4000 - 10000/μL). Stool tests were negative for enteropathogenic bacteria and Clostridium difficile toxins A/B. Ultrasound and computed tomography showed massive swelling of the transverse colon and right colonic flexure. At endoscopy, circular necrosis of the mucosa was encountered in the proximal segments of the colon whereas distal parts of the organ showed patchy inflammation of minor severity. Extended stool testing identified Escherichia coli type O104:H4 as the causative microorganism. There was no evidence for haemolytic uraemic syndrome. Under conservative treatment the patient recovered clinically, serologically and endoscopically. At follow-up endoscopy, longitudinal ulcers and vital mucosa were present. In this case report the segmental pattern of mucosal necrosis in a patient with EHEC infection is noteworthy.
journal_name
Z Gastroenteroljournal_title
Zeitschrift fur Gastroenterologieauthors
Scheppach W,Reissmann N,Breunig E,Konwisorz A,Schwarz TF,Müller JG,Tappe Ddoi
10.1055/s-0031-1299289subject
Has Abstractpub_date
2012-02-01 00:00:00pages
209-12issue
2eissn
0044-2771issn
1439-7803journal_volume
50pub_type
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