Abstract：
:Phytochemical investigation of seed coats of Pterospermum acerifolium afforded two phytoceramides (1, 2) and two acylated phytosterol glucosides (3, 4) together with five known compounds (5-9). Their structures were elucidated on the basis of extensive spectroscopic analysis using 1D, 2D NMR and Mass spectrometry. Compounds 1, 2, 3, and 4 were assessed for their osteogenic activity using primary cultures of osteoblasts harvested from neonatal rat calvaria. Among these compounds, 1 and 2 markedly stimulated osteoblast differentiation assessed by alkaline phosphatase production and osteoblast mineralization by alizarin red-S staining.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Dixit P,Chand K,Khan MP,Siddiqui JA,Tewari D,Ngueguim FT,Chattopadhyay N,Maurya Rdoi
10.1016/j.phytochem.2012.06.005subject
Has Abstractpub_date
2012-09-01 00:00:00pages
117-25eissn
0031-9422issn
1873-3700pii
S0031-9422(12)00261-0journal_volume
81pub_type
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