Abstract：
OBJECTIVE:To identify the variables associated with sepsis-associated mortality, as well as to develop a severity risk score to predict death in very low-birth-weight (VLBW) neonates affected by nosocomial sepsis. STUDY DESIGN:Retrospective cohort study. Infants weighing ≤ 1500 g with neonatal sepsis of nosocomial origin were included. Epidemiological, clinical, and laboratory variables were recorded at onset (0 hours), at 12 hours, and at 24 hours. Bivariate and multivariate analyses were performed. RESULT:The study population included 95 VLBW infants who presented 129 episodes of nosocomial sepsis. In the bivariate analysis, gram-negative bacilli as the etiology of sepsis, seizures, age, postconceptional age, weight, serum procalcitonin (24 hours), platelet count (24 hours), blood urea nitrogen (0 and 24 hours), creatinine (24 hours), diuresis (12 and 24 hours), mean blood pressure (12 and 24 hours), pH, base excess (0, 12, and 24 hours), and SpO(2) (pulse oximetric saturation):F(IO(2)) (fraction of inspired oxygen) ratio (12 and 24 hours) were significantly associated with mortality. In the multivariate analysis, weight at the onset of sepsis, base excess (0 hours), and SpO(2):F(IO(2)) ratio (12 hours) were independent predictors of mortality. CONCLUSION:A lower weight at the onset of sepsis, base excess, and SpO(2):F(IO(2)) ratio are useful to predict nosocomial sepsis-associated mortality in VLBW infants.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Prieto CL,Colomer BF,Sastre JBdoi
10.1055/s-0032-1324701subject
Has Abstractpub_date
2013-05-01 00:00:00pages
353-8issue
5eissn
0735-1631issn
1098-8785journal_volume
30pub_type
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journal_title：American journal of perinatology
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journal_title：American journal of perinatology
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journal_title：American journal of perinatology
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journal_title：American journal of perinatology
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journal_title：American journal of perinatology
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更新日期：2019-05-01 00:00:00
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journal_title：American journal of perinatology
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journal_title：American journal of perinatology
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doi：10.1055/s-2007-999800
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更新日期：2018-11-01 00:00:00
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更新日期：2020-12-15 00:00:00
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更新日期：2009-05-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993914
更新日期：1998-02-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2002-20175
更新日期：2002-01-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
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更新日期：1992-09-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0033-1347363
更新日期：2014-03-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0037-1598244
更新日期：2017-07-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1552934
更新日期：2015-11-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2004-831888
更新日期：2004-08-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994724
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journal_title：American journal of perinatology
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更新日期：2012-10-01 00:00:00
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更新日期：2017-03-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2005-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-11-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1563548
更新日期：2016-01-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994064
更新日期：1998-01-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章,评审
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更新日期：2009-01-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the role of first-trimester uterine artery Doppler in the prediction of recurrent preeclampsia (PE). METHODS:Uterine artery pulsatility index (UtPI) was measured at 11 to 13 weeks' gestation in 1,810 women with singleton pregnancies who had developed PE in a previous pregnancy. They were categori...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0033-1338172
更新日期：2014-02-01 00:00:00
