Abstract:
AIM:To prospectively evaluate and compare the potential of various diffusion metrics obtained from mono-exponential model (MEM), bi-exponential model (BEM), and stretched exponential model (SEM)-based diffusion-weighted imaging (DWI) in the grading of meningiomas. MATERIAL AND METHODS:Consecutive 93 patients with histopathologically confirmed meningiomas received DWI of multiple b-values. Apparent diffusion coefficient (ADC), pure molecular diffusion (D), pseudo-diffusion coefficient (D*), perfusion fraction (f), water molecular diffusion heterogeneity index (alpha), and distributed diffusion coefficient (DDC) were calculated and compared between low-grade and high-grade meningiomas. Receiver operating characteristic and multivariable stepwise logistic regression analyses were performed to evaluate the diagnostic performance of different parameters. RESULTS:The mean and normalised ADC, D, f, and DDC values were significantly lower in high-grade meningiomas than those in low-grade meningiomas (all p<0.05). The AUCs of D and DDC were significantly higher than that of f in the differentiation (all p<0.05). D was the only variable that could be used to independently differentiate high-grade and low-grade meningiomas (p<0.001). CONCLUSION:Different models of DWI, including MEM, BEM, and SEM, are useful in the differentiating high-grade and low-grade meningiomas; however, D obtained from BEM is the most promising diffusion parameter for predicting the grade of meningiomas.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Lin L,Xue Y,Duan Q,Chen X,Chen H,Jiang R,Zhong T,Xu G,Geng D,Zhang Jdoi
10.1016/j.crad.2019.04.007subject
Has Abstractpub_date
2019-08-01 00:00:00pages
651.e15-651.e23issue
8eissn
0009-9260issn
1365-229Xpii
S0009-9260(19)30194-1journal_volume
74pub_type
杂志文章abstract::Three patients with pancreatic clonorchiasis were examined with endoscopic retrograde pancreatography. On each of the three cases there was diffuse irregular dilatation of tributaries of the pancreatic duct in the pancreatic tail. The main pancreatic duct and tributaries draining into the body and head portion were no...
journal_title:Clinical radiology
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pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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journal_title:Clinical radiology
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journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1979-07-01 00:00:00
abstract::In a prospective study 59 consecutive outpatients having double-contrast barium enemas (DCBE) were randomised into four groups. Each group had their enema performed at either a 15, 30, 45 or 60 minute interval following the end of a 1.5 litre cleansing water enema. Review of the films by two radiologists demonstrated ...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
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abstract:AIM:To evaluate the image quality of contrast-enhanced chest computed tomography (CT) with low tube voltage settings using an iterative reconstruction algorithm (iDose4) and standard dose filtered back projection (FBP) CT in patients with normal body mass index (BMI). MATERIALS AND METHODS:Eighty patients with normal ...
journal_title:Clinical radiology
pub_type: 杂志文章,随机对照试验
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更新日期:2013-05-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(99)91071-1
更新日期:1999-02-01 00:00:00
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journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1981-09-01 00:00:00