Abstract:
PURPOSE:To investigate the value of viscosity measured with ultrasonographic (US) elastography in liver fibrosis staging and to determine whether the use of a viscoelastic model to estimate liver elasticity can improve its accuracy in fibrosis staging. MATERIALS AND METHODS:The study, which was performed from February 2010 to March 2011, was compliant with HIPAA and approved by the institutional review board. Written informed consent was obtained from each subject. Ten healthy volunteers (eight women and two men aged 27-55 years) and 35 patients with liver disease (17 women and 18 men aged 19-74 years) were studied by using US elasticity measurements of the liver (within 6 months of liver biopsy). US data were analyzed with the shear wave dispersion ultrasound vibrometry (SDUV) method, in which elasticity and viscosity are measured by evaluating dispersion of shear wave propagation speed, as well as with the time-to-peak (TTP) method, where tissue viscosity was neglected and only elasticity was estimated from the effective shear wave speed. The hepatic fibrosis stage was assessed histologically by using the METAVIR scoring system. The correlation of elasticity and viscosity was assessed with the Pearson correlation coefficient. The performances of SDUV and TTP were evaluated with receiver operating characteristic (ROC) curve analysis. RESULTS:The authors found significant correlations between elasticity and viscosity measured with SDUV (r = 0.80) and elasticity measured with SDUV and TTP (r = 0.94). The area under the ROC curve for differentiating between grade F0-F1 fibrosis and grade F2-F4 fibrosis was 0.98 for elasticity measured with SDUV, 0.86 for viscosity measured with SDUV, and 0.95 for elasticity measured with TTP. CONCLUSION:The results suggest that elasticity and viscosity measured between 95 Hz and 380 Hz by using SDUV are correlated and that elasticity measurements from SDUV and TTP showed substantially similar performance in liver fibrosis staging, although elasticity calculated from SDUV provided a better area under the ROC curve.
journal_name
Radiologyjournal_title
Radiologyauthors
Chen S,Sanchez W,Callstrom MR,Gorman B,Lewis JT,Sanderson SO,Greenleaf JF,Xie H,Shi Y,Pashley M,Shamdasani V,Lachman M,Metz Sdoi
10.1148/radiol.12120837subject
Has Abstractpub_date
2013-03-01 00:00:00pages
964-70issue
3eissn
0033-8419issn
1527-1315pii
radiol.12120837journal_volume
266pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::Nineteen patients with unequivocal angiographic evidence of unilateral or bilateral posterior cerebral artery occulsion were scanned during the acute phase of the stroke. In 12 of them an abnormal accumulation of radioactivity was apparent on the posterior view, but only 2 also exhibited abnormal uptake on the corresp...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/123.2.393
更新日期:1977-05-01 00:00:00
abstract::Angiographic ablation of parathyroid adenomas with ionic contrast material was performed in 24 patients with persistent hyperparathyroidism who had undergone at least one prior unsuccessful surgical resection; 23 had mediastinal adenomas. The success rate was 83% at 1 month after ablation and 71% at both 5 and 9 years...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.165.3.3685340
更新日期:1987-12-01 00:00:00
abstract::Five cases, four histologically proved, or hamartoma of the tuber cinereum and hypothalamus in children (age range: 2--12 years) are reported. Three cases had pubertas praecox, and in all of these the hamartoma was located in the basal cistern between the chiasm and pons, and had a collar button shape and size typical...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/127.3.697
更新日期:1978-06-01 00:00:00
abstract::An aortobronchial fistula is a rare condition that is invariably fatal if not diagnosed and surgically treated. Aortic aneurysms, both atherosclerotic and infective, were the main causes in the originally described cases. However, thoracic cardiovascular surgery has recently become the predominant cause. The authors d...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.175.2.2326460
更新日期:1990-05-01 00:00:00
abstract::The value of computed tomography (CT) in determining the cause of obstructive jaundice in 67 proved cases is described. The presence of stones, the level of obstruction, the relative size of the ringlike structures produced by the dilated bile duct, and the shape of the distal visualized ring have proved to be the mos...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.139.3.7232730
更新日期:1981-06-01 00:00:00
abstract:PURPOSE:To assess the feasibility of hybrid imaging of the heart with fluorine 18 fluorodeoxyglucose (FDG) on an integrated 3-T positron emission tomography (PET)/magnetic resonance (MR) imaging system. MATERIALS AND METHODS:The present study was approved by the local institutional review board. Written informed conse...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.13130231
更新日期:2013-08-01 00:00:00
abstract::Hyperpolarized metabolic magnetic resonance (MR) imaging offers greatly enhanced sensitivity to multinuclear MR spectroscopy, opening up a new tool with which to noninvasively assess metabolic changes in the diseased heart. In this issue of Radiology, O h-Ici et al ( 1 ) have demonstrated this ability by exploring the...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2016152489
更新日期:2016-03-01 00:00:00
abstract::Twenty-five infants and children with proved gastroesophageal reflux were studied by radionuclide gastroesophagography to determine its sensitivity in detecting reflux. Patients swallowed an inert radiotracer (Tc-99m sulfur colloid) and gamma camera images of the stomach and esophagus were made with and without abdomi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/131.2.483
更新日期:1979-05-01 00:00:00
abstract::Recent reports have indicated that non-contrast material-enhanced scans are of less value than urographic contrast material-enhanced studies in the computed tomographic (CT) evaluation of hepatic metastases. The authors retrospectively reviewed the CT scans of 28 patients with hypervascular liver metastases to determi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.162.1.3024210
更新日期:1987-01-01 00:00:00
abstract:PURPOSE:To evaluate the effect of scanner type and calcium measure on the reproducibility of calcium measurements. MATERIALS AND METHODS:This investigation was approved by the institutional review boards of each study site and by the Institutional Review Board of the Los Angeles Biomedical Research Institute. Informed...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiol.2362040513
更新日期:2005-08-01 00:00:00
abstract::Institutional review board approval and informed consent were obtained. This study was conducted to evaluate a newly developed technique for discriminative color coding of tagged stool during three-dimensional (3D) endoluminal fly-through computed tomographic (CT) colonography and to determine its effect on reading ef...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2483071645
更新日期:2008-09-01 00:00:00
abstract::Ankle trauma commonly results in significant injury. Knowledge of the anatomy of the normally nonopaque major supportive ligaments, and their relationships to the osseous structures seen on standard roentgenograms, facilitates interpretation of both plain films and ankle arthrograms. A group of normal, non-preserved a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/125.3.659
更新日期:1977-12-01 00:00:00
abstract:PURPOSE:To increase the capabilities of ultrasonographic (US) technology for the differential diagnosis of solid breast tumors by using a neural network. MATERIALS AND METHODS:One hundred forty US images of solid breast nodules were evaluated. When a sonogram was obtained, an analog video signal from the VCR output of...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.213.2.r99nv13407
更新日期:1999-11-01 00:00:00
abstract:PURPOSE:To compare areas of contrast material enhancement in the prostate at ultrasonography (US) with whole-mount radical prostatectomy specimens to determine if the use of contrast material improves the detection rate of prostate cancer. MATERIALS AND METHODS:Transrectal US was performed in 12 subjects with cancer o...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2222010582
更新日期:2002-02-01 00:00:00
abstract::Sun et al used pigs to evaluate transcatheter arterial embolization (TAE) as a potential treatment for benign prostatic hyperplasia (BPH). Although more data regarding the effectiveness, durability, and side effects of TAE are needed, it may prove to be competitive with other accepted forms of treatment. ...
journal_title:Radiology
pub_type: 评论,杂志文章
doi:10.1148/radiol.2463071721
更新日期:2008-03-01 00:00:00
abstract::Background Cardiac MRI late gadolinium enhancement (LGE) scar volume is an important marker for outcome prediction in patients with hypertrophic cardiomyopathy (HCM); however, its clinical application is hindered by a lack of measurement standardization. Purpose To develop and evaluate a three-dimensional (3D) convolu...
journal_title:Radiology
pub_type: 杂志文章,多中心研究
doi:10.1148/radiol.2019190737
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To evaluate the use of a redundant system in improving quality of care in the trauma setting by examining a subset of our quality assurance program. MATERIALS AND METHODS:Five hundred thirty-one consecutive abdominal and pelvic CT reports obtained in patients with trauma at a level I trauma center from August ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2241011470
更新日期:2002-07-01 00:00:00
abstract::Patients who carry the BRCA1 and BRCA2 gene mutations have an underlying genetic predisposition for breast and ovarian cancers. These deleterious genetic mutations are the most common genes implicated in hereditary breast and ovarian cancers. This monograph summarizes the evidence behind current screening recommendati...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiol.2019181814
更新日期:2019-06-01 00:00:00
abstract::This case series describes the radiologic appearances of gynecomastoid hyperplasia of the breast in our experience. The clinical histories, breast images, and histopathologic findings in six women were reviewed. At mammography, there was no abnormality in two women, an enlarging asymmetric density in three women, and ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.214.2.r00fe24553
更新日期:2000-02-01 00:00:00
abstract::A cancellation of signal intensity at the interface separating selected tissue-equivalent materials is observed in inversion recovery proton MR images. The absence of signal intensity at the interface is always one pixel wide and appears only when the tissue-equivalent materials forming the interface differ substantia...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.160.2.3014600
更新日期:1986-08-01 00:00:00
abstract::Ultrasound scanning is useful in evaluating renal transplants: it is atraumatic, independent of renal function, and well suited for analyzing such common complications as lymphocele, abscess, hydronephrosis, and hematoma. When there is uncertainty as to the nature of a paranephric mass, ultrasonically guided percutane...
journal_title:Radiology
pub_type: 杂志文章
doi:
更新日期:1976-02-01 00:00:00
abstract::High-resolution, real-time ultrasonography (US) with graded compression was used to evaluate 90 patients with clinically suspected acute appendicitis. US visualization of a noncompressible appendix was the primary criterion for a diagnosis of acute appendicitis. The overall sensitivity was 89%, the specificity was 95%...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.163.1.3547490
更新日期:1987-04-01 00:00:00
abstract:PURPOSE:To measure both volume and signal intensity of the fetal lung at magnetic resonance (MR) imaging and to evaluate the clinical use of this method to predict fetal pulmonary hypoplasia. MATERIALS AND METHODS:A total of 87 fetuses evaluated with MR imaging at 24-39 weeks of gestation were classified into a contro...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2313021689
更新日期:2004-06-01 00:00:00
abstract::As computer networks become an integral part of the radiology practice, it is appropriate to raise concerns regarding their security. The purpose of this article is to present an overview of computer network security risks and preventive strategies as they pertain to the radiology enterprise. A number of technologies ...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiology.220.2.r01au32303
更新日期:2001-08-01 00:00:00
abstract::In a retrospective study, thin-walled cystic lesions were identified in four patients with proved bronchioalveolar carcinoma (BAC). The radiographic appearances are described, and possible mechanisms of formation of the lesions are discussed. Although such appearances due to BAC have rarely been described in the liter...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.185.2.1329140
更新日期:1992-11-01 00:00:00
abstract::Positron emission tomography (PET) provides metabolic information that has been documented to be useful in patient care. The properties of positron decay permit accurate imaging of the distribution of positron-emitting radiopharmaceuticals. The wide array of positron-emitting radiopharmaceuticals has been used to char...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiol.2312021185
更新日期:2004-05-01 00:00:00
abstract::A recently developed duplex ultrasonic imaging system that combines high-resolution real-time imaging with simultaneous Doppler analysis provides accurate evaluation of hemodynamically significant occlusive vascular lesions. This system was used in the evaluation of the extracranial carotid arteries, iliofemoral arter...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.150.2.6691110
更新日期:1984-02-01 00:00:00
abstract:PURPOSE:To assess interobserver and intraobserver reliability of three quantitative measures of coronary artery calcium burden: calcium "score," number of calcified lesions, and calcified area. MATERIALS AND METHODS:Electron beam computed tomographic (CT) scanning was used in a series of 25 patients to detect coronary...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.190.2.8284380
更新日期:1994-02-01 00:00:00
abstract:PURPOSE:To evaluate clinically suspected Morton neuroma with contrast material-enhanced magnetic resonance (MR) images. MATERIALS AND METHODS:Fifteen patients with clinically suspected Morton neuroma underwent examination with conventional T1- and T2-weighted MR imaging and a combination of fat suppression and adminis...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.189.1.8372200
更新日期:1993-10-01 00:00:00
abstract::Cathartic colon has been described radiologically, but the pathological characteristics have not been reported. The authors describe a case in which radiological/pathological correlation was possible, with emphasis on the pathology of the colon. The disease simulates chronic ulcerative colitis radiologically and patho...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/116.3.557
更新日期:1975-09-01 00:00:00