Abstract：
INTRODUCTION AND HYPOTHESIS:Presence of microbial communities (microbiota) in an organ system depends on environmental factors, such as oxygen availability. We describe a novel technique to measure bladder urine oxygen tension (BUOT) in ambulatory women and use that technique to compare BUOT values to female urinary microbiota and participant urinary signs and symptoms. METHODS:Ambulatory female urogynecology patients presenting for clinical care who were willing to undergo transurethral catheterization underwent BUOT determination with a non-invasive flow-through oxygen sensor. To detect urinary microbiota in the bladder, 16S rRNA gene sequencing was performed on catheterized urine. Multivariate statistical analyses were performed to examine potential correlations among BUOT, urinary microbiota compositions and clinical variables. RESULTS:Significant variation in BUOT existed between individuals (range: 0.47-51.5 mmHg; median: 23.1 ± 13.5). Microbiota compositions were associated with BUOT (p = 0.03). BUOT was significantly lower in urines that were nitrite negative on dipstick analysis (p = 0.0001) and in participants who answered yes to having urinary leakage on the validated Urinary Distress Inventory (p = 0.01). CONCLUSIONS:BUOTs can be measured in ambulatory women. For urogynecology patients, a wide range of values exist. BUOT may be associated with the presence of urinary microbiota and resultant signs and symptoms.
journal_name
Int Urogynecol Jjournal_title
International urogynecology journalauthors
Shannon MB,Limeira R,Johansen D,Gao X,Lin H,Dong Q,Wolfe AJ,Mueller ERdoi
10.1007/s00192-019-03931-ysubject
Has Abstractpub_date
2019-08-01 00:00:00pages
1261-1267issue
8eissn
0937-3462issn
1433-3023pii
10.1007/s00192-019-03931-yjournal_volume
30pub_type
杂志文章abstract：INTRODUCTION AND HYPOTHESIS:To evaluate the efficacy and safety of the intravesical injection of Chinese botulinum toxin A (BTX-A) in patients with interstitial cystitis/bladder pain syndrome (IC/BPS). METHODS:Between January 2003 and June 2013, 124 women with IC/BPS were studied. Of these 124 patients, 66 were treate...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-015-2631-y
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVES:To report 12-year experience with replacing transvaginal mesh (TVM) with fascia lata autograft. METHODS:This was a chart review of TVM removal and replacement with a fascia lata autograft placement by a single surgeon between 2005 and 2017. The Pelvic Organ Prolapse Quantification (POP-Q) system before and ...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-019-03957-2
更新日期：2019-09-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:The objective of this study was to measure the effects of pregnancy and parturition on pelvic floor muscles and pelvic organ support. METHODS:Levator ani, obturator internus, and coccygeus (COC) muscle volumes and contrast uptake were assessed by MRI of seven females prior to pregnancy, 3 d...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-011-1443-y
更新日期：2011-09-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Obstetric anal sphincter injury (OASIS) rates are reported to be higher in Asian women living in Western countries than in those living in Asia, but the reasons for the differences remain unclear. The objectives of this study were for a single examiner to prospectively compare OASIS rates in...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-018-3649-8
更新日期：2019-03-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:The aim of the mediolateral episiotomy incision is to increase the diameter of the soft tissue of the vaginal outlet to facilitate birth and to prevent vaginal tears. Episiotomy angles that are too narrow and close to the midline increase the risk of obstetric anal sphincter injuries. In ord...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-017-3349-9
更新日期：2017-12-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Missing data is frequently observed in clinical trials; high rates of missing data may jeopardize trial outcome validity. PURPOSE:We determined the rates of missing data over time, by type of data collected and compared demographic and clinical factors associated with missing data among wom...
journal_title：International urogynecology journal
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00192-015-2661-5
更新日期：2015-08-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:St Mark's incontinence score (SMIS) and the Wexner score have been constructed and validated as interview-based scoring systems. We developed a single questionnaire from which a separate SMIS or Wexner score could be derived. This study aimed to demonstrate the level of agreement between sel...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-019-03945-6
更新日期：2019-12-01 00:00:00
abstract：INTRODUCTION:Lower urinary tract symptoms (LUTS) in subjects with Mayer-Rokitansky-Küster-Hauser syndrome treated by Davydov's laparoscopic neo-vaginoplasty were measured. METHODS:Davydov's laparoscopic neo-vaginoplasty was undertaken at the Department of Obstetrics/gynecology, San Raffaele Hospital, Milan, Italy, fro...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-020-04311-7
更新日期：2020-12-01 00:00:00
abstract：INTRODUCTION:InTone(TM) (InControl Medical) is a nonimplanted vaginal device providing biofeedback and electrical stimulation of pelvic floor muscles. The purpose of this study was to assess its efficacy and usability for treating urinary incontinence (UI). METHODS:Women with UI (stress, urge, mixed) were recruited fo...
journal_title：International urogynecology journal
pub_type： 临床试验,杂志文章
doi：10.1007/s00192-014-2476-9
更新日期：2015-01-01 00:00:00
abstract：:Combining anti-incontinence and pelvic organ prolapse surgery for patients with occult urinary stress incontinence is controversial. The concern is that some of these patients may remain continent after vaginal prolapse repair making the addition of anti-incontinence surgery unnecessary. However, this can be explained...
journal_title：International urogynecology journal
pub_type： 杂志文章,评审
doi：10.1007/s00192-011-1563-4
更新日期：2012-07-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:The aim of the study was to assess the interobserver and intraobserver reliability of translabial 3D ultrasound imaging of the urethral sphincter in non-pregnant nulliparous asymptomatic women. METHODS:A study using a 3D translabial ultrasound on thirty-seven women was performed. Urethral s...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-012-1669-3
更新日期：2012-08-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Stress urinary incontinence (SUI) may appear after the correction of pelvic organ prolapse (POP). The aim of this study was to externally validate a described predictive model for de novo SUI and to assess its clinical performance when used as a diagnostic test. METHODS:This was a retrospec...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-018-3805-1
更新日期：2019-10-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:We present a video reviewing the key steps involved in safe anterior cul-de-sac entry during vaginal hysterectomy, including tips for troubleshooting difficult cases such as: uterine procidentia, cervical elongation, and multiple prior cesarean sections. METHODS:Anterior cul-de-sac entry is...
journal_title：International urogynecology journal
pub_type： 杂志文章,评审
doi：10.1007/s00192-018-3646-y
更新日期：2018-08-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Pelvic floor muscles (PFM) are deleteriously affected by vaginal birth, which contributes to the development of pelvic floor disorders. To mechanistically link these events, experiments using animal models are required, as access to human PFM tissue is challenging. In choosing an animal mode...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-014-2423-9
更新日期：2014-11-01 00:00:00
abstract：INTRODUCTION:This study investigated perioperative and mid-term clinical outcomes after laparoscopic sacrocolpopexy (LSCP) with light titanium-coated polypropylene (TCP) mesh in a large group of patients affected by International Continence Society stage II-IV pelvic organ prolapse (POP). METHODS:This multicenter retr...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-019-04146-x
更新日期：2020-04-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:The aim of the study was to evaluate the predictors and reasons for help-seeking behavior among women with urinary incontinence (UI) in Germany and Denmark. METHODS:This international postal survey was conducted in 2014. In each country, 4,000 women of at least 18 years of age were randomly...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-017-3434-0
更新日期：2018-04-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:This study evaluated the efficacy and tolerability of transcutaneous posterior tibial nerve stimulation (TPTNS) in the treatment of overactive bladder (OAB) after failure of a first-line anticholinergic treatment. MATERIALS AND METHODS:We performed a prospective observational study and incl...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-014-2359-0
更新日期：2014-08-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Mediolateral episiotomy is one of the most frequent surgical interventions performed in obstetrics. There is conflicting evidence as to whether mediolateral episiotomy reduces the risk of obstetric anal sphincter injuries (OASI). Recent studies suggest that functional asymmetry of pelvic flo...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-018-3560-3
更新日期：2018-10-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:World Health Organisation (WHO) data suggest that more than two million women and girls live with fistula and that an additional 50-100,000 are newly affected each year. In Tanzania, it has been estimated that there are between 1,200 and 3,000 new cases of obstetric fistula annually. METHOD...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-013-2185-9
更新日期：2014-02-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:The aim of this study was to compare the results of pelvic organ prolapse repair using a capturing device-guided transvaginal mesh in a single- vs multicenter setting. METHODS:One hundred and twelve women operated by two surgeons at one center (2-year follow-up) were compared with 207 women...
journal_title：International urogynecology journal
pub_type： 杂志文章,多中心研究
doi：10.1007/s00192-017-3364-x
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:This study assessed the safety and efficacy of vaginal extraperitoneal uterosacral ligament suspension (VEULS) with anterior overlay mesh versus sacrocolpopexy (SCP) for posthysterectomy vault prolapse. METHODS:This was a multicenter randomized trial of women with posthysterectomy vault pro...
journal_title：International urogynecology journal
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00192-018-3687-2
更新日期：2018-11-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Stress urinary incontinence (SUI) is treated using intravaginal laser therapy. We wanted to find out how incontinence severity at baseline and the number of laser interventions affect success rate, and whether the effect of laser therapy was obvious 6 months and 2 years after the last laser ...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-019-04148-9
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of soy isoflavone extract (SIE) on the uterus and urethra of castrated female rats. METHODS:Ovariectomized adult virgin Wistar rats (n = 45) received, for 30 days: placebo (GI); SIE from day 5 of castration (GII); or day 28 of castration (GIII). A standardized SIE was administered by g...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-009-0995-6
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Double Incontinence (DI) is incontinence of urine and stool and is an extreme manifestation of pelvic floor dysfunction. The objective of this study was to estimate the prevalence and incidence of DI and the risk factors in elderly women in São Paulo, Brazil. METHODS:This was a prospective ...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-017-3365-9
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:Nocturia is the number of times urine is passed during main sleep. This definition tells us that it is a need to void; it does not tell us what triggers it. The aim of this study is to report bladder sensations that wake up women with nocturia (N). Descriptions of sensations in relation to various overactive...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-020-04257-w
更新日期：2020-05-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:The effect of pregnancy and mode of delivery on pelvic floor muscle function (PFMF) is unclear. Our aim was to prospectively evaluate the effect of pregnancy and childbirth on PFMF. METHODS:Subjective (Oxford scale) and objective (perineometry) assessments of PFMF were performed at 20 and 3...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-011-1501-5
更新日期：2011-11-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Posthysterectomy vaginal vault prolapse repair is a challenge for urogynecologists. Surgical management can be successful with native tissue by the vaginal approach with sacrospinous ligament fixation. However, severe complications have been described, including nerve injury and life-threate...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-016-3255-6
更新日期：2017-07-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:We sought to compare rates of recurrent cystocele following sacrocolpopexy with and without paravaginal repair (PVR). METHODS:This retrospective cohort study compared outcomes for patients undergoing sacrocolpopexy with (group A) and without (group B) concomitant PVR. Defining anterior fail...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-009-1013-8
更新日期：2010-03-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Bladder pain syndrome (BPS) is a disease of unknown etiology defined as an unpleasant sensation related to the bladder, associated with lower urinary tract symptoms of more than 6 weeks' duration, in the absence of any identifiable causes. Despite its impact on quality of life (QoL) and soci...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-019-04075-9
更新日期：2019-11-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Circumferential vesicourethrovaginal fistula is a severe form of obstetric injury that is challenging to repair and carries a poor prognosis related to eventual continence. Here, we report the successful repair of a circumferential vesicovaginal fistula associated with near total loss of the...
journal_title：International urogynecology journal
pub_type： 杂志文章
doi：10.1007/s00192-020-04398-y
更新日期：2020-06-23 00:00:00
