Abstract:
INTRODUCTION AND HYPOTHESIS:To evaluate the efficacy and safety of the intravesical injection of Chinese botulinum toxin A (BTX-A) in patients with interstitial cystitis/bladder pain syndrome (IC/BPS). METHODS:Between January 2003 and June 2013, 124 women with IC/BPS were studied. Of these 124 patients, 66 were treated with BTX-A and 58 underwent bladder hydrodistention plus sodium hyaluronate (Cystistat) instillation. Intravesical injection of 100 U of Chinese BTX-A was immediately followed by cystoscopic hydrodistention under intravenous general anesthesia. The patients were evaluated using the O'Leary-Saint score, a visual analog scale pain score, a urinary frequency record and a quality of life questionnaire before treatment and 1 week, and 1, 3, 6 and 12 months after treatment. RESULTS:Of the patients who received BTX-A injection, only 2 had acute urinary retention, 23 received a repeat injection, and 20 were lost to follow-up. Of the patients treated with hydrodistention plus Cystistat instillation, 2 had urinary tract infection, 11 switched to BTX-A injection at 6 months, and 23 were lost to follow-up. BTX-A was shown to remain effective for up to 6 months after treatment. After repeated Chinese BTX-A injections, symptoms improved significantly. Hydrodistention plus Cystistat remained effective for up to 3 months after treatment. CONCLUSIONS:Intravesical injection of Chinese BTX-A is a safe and effective therapeutic option for patients with IC/BPS. The average duration of the effect of one dose of Chinese BTX-A amongst the responders was 6 months. Repeated injection of Chinese BTX-A is safe and effective.
journal_name
Int Urogynecol Jjournal_title
International urogynecology journalauthors
Gao Y,Liao Ldoi
10.1007/s00192-015-2631-ysubject
Has Abstractpub_date
2015-07-01 00:00:00pages
1021-6issue
7eissn
0937-3462issn
1433-3023journal_volume
26pub_type
杂志文章abstract:INTRODUCTION AND HYPOTHESIS:No previous studies have investigated the efficacy of mirabegron 50 mg as the first-line therapy in OAB patients. Hence, the primary objective of this study was to evaluate the efficacy of mirabegron in treatment-naive patients in comparison with those who had discontinued antimuscarinic the...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3219-x
更新日期:2017-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The literature presents controversial results regarding the role of delivery mode in pelvic floor muscle (PFM) function after birth. Some studies showed a greater impairment of PFM function after vaginal delivery compared with cesarean section, while others have not identified a significant ...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-020-04231-6
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To estimate the incidence rates of stress urinary incontinence (SUI) surgery among Finnish women from 1987 to 2009 by age, and to evaluate the trends in SUI surgery. METHODS:We conducted a retrospective register-based study. All SUI procedures on adult women over age 18 years in Finland wer...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2926-z
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:Concerns about vaginal mesh have reduced the use of mid-urethral slings (MUS) in some countries. In view of their potential withdrawal in Belgium and The Netherlands, we polled urogynaecologists on their practice for treating stress urinary incontinence (SUI) and what their experience is with alternative p...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-019-04135-0
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Different techniques of mesh placement for cystocele repair are known. Our goal was to compare anatomical and functional outcomes of three different techniques of mesh placement over a 3-year follow-up. METHODS:Between March 2003 and June 2004, 230 patients (stage 2-4 pelvic organ prolapse ...
journal_title:International urogynecology journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00192-011-1650-6
更新日期:2012-06-01 00:00:00
abstract::Clinical manifestations of vesicouterine fistulas, a rare complication of cesarean section, include amenorrhea and cyclic hematuria (menouria) without urinary incontinence, a triad collectively known as "Youssef's syndrome." Fistulas affecting the uterus usually reside above the isthmus or at the cervix and have a dis...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1849-1
更新日期:2013-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Ureteral injury during gynecological surgery can be managed in a variety of ways, from endoscopic stent placement to ureteroneocystotomy with accompanying psoas hitch and/or Boari flap. The majority of these occur during hysterectomy; therefore, gynecologic surgeons may not be as familiar wi...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04627-4
更新日期:2021-01-06 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:This study was designed to assess the effect of gynecological morbidities on Mexican women's self-rated health status and emotional health. METHODS:A cross-sectional population-based study was conducted among Mexican women aged 25-54. We analyzed information on 1,303 participants living in ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3537-7
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of soy isoflavone extract (SIE) on the uterus and urethra of castrated female rats. METHODS:Ovariectomized adult virgin Wistar rats (n = 45) received, for 30 days: placebo (GI); SIE from day 5 of castration (GII); or day 28 of castration (GIII). A standardized SIE was administered by g...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-009-0995-6
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Intravesical onabotulinumtoxinA (Botox) injections are effective for the treatment of idiopathic overactive bladder (OAB) symptoms. The aim of our study was to assess the predisposing factors for urinary retention in women with OAB after intravesical Botox injection. METHODS:All participant...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3212-4
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Polypropylene meshes are frequently used in abdominal and vaginal reconstructive surgery. Recently, several authors have claimed that mesh-associated complications may be linked to mesh shrinkage. We have performed a prospective study with postoperative follow-up by ultrasound examination at...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1308-9
更新日期:2011-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To study the prevalence and risk factors of overactive bladder (OAB) symptoms and its relationship with symptoms of pelvic organ prolapse (POP). METHODS:This is a cross-sectional study including women aged between 45 and 85 years, registered in eight general practices. All women were asked ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1323-x
更新日期:2011-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Older studies suggesting an association between detrusor overactivity and bacteriuria used an outdated microbiological threshold. We hypothesised that bacteriuria ≥10(3) CFU/ml would be more prevalent in women with urinary incontinence than continent controls. METHODS:A prospective, cross-s...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1506-0
更新日期:2011-10-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:There seems to be a temporal association between increasing use of "hands off" the perineum in labour and reduced use of episiotomy with an increasing rate of anal sphincter injuries. We aimed to determine how common the practice of "hands off" the perineum is. METHODS:An observational post...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1454-8
更新日期:2011-10-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We evaluated the surgical feasibility, sexual satisfaction and complications of vaginal reconstruction with sigmoid colon in patients with congenital absence of vagina and menses retention. METHODS:Retrospective analysis of surgical techniques and long-term postoperative follow-up was perfo...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1799-7
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Female sexual function disorders (FSFDs) have received less attention than male sexual function disorders, despite being more prevalent. Furthermore, most available literature is on the effect of vaginal delivery (VD) on sexual function, and studies on the effect of caesarean section (CS) ar...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04541-9
更新日期:2020-10-10 00:00:00
abstract::In this article, we provide a concise review of the literature on nocturia and its interference with sleep and, consequently, on quality of life. There are few studies addressing the possible influences of nocturia on sleep disruption. Nocturia is a potential contributor to sleep disorders because affected individuals...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-011-1525-x
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The effect of exercise in relation to overweight and overactive bladder (OAB) in young women has not been sufficiently supported by studies. The objective of our study was to reduce symptoms of OAB through a 3-month exercise programme in young overweight women with OAB. The sample consisted ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-04157-8
更新日期:2020-05-01 00:00:00
abstract::Oxybutynin chloride is primarily indicated for the treatment of overactive bladder syndrome (OAB). It remains the most widely prescribed compound for OAB in the world. OAB is defined as the presence of urinary urgency, usually accompanied by daytime urinary frequency and nocturia, with or without urgency urinary incon...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-012-1915-8
更新日期:2013-04-01 00:00:00
abstract::The article "Impact of surgeon experience on routine prolapse operations", written by Emil Nüssler, Jacob Kjær Eskildsen, Emil Karl Nüssler, Marie Bixo, and Mats Löfgren, was originally published without open access. ...
journal_title:International urogynecology journal
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00192-017-3525-y
更新日期:2018-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:This time-series analysis was carried out to determine if the use of the EPISCISSORS-60®, episiotomy scissors specifically designed to achieve a cutting angle of 60°, would continue to sustain obstetric anal sphincter injuries (OASIS) reductions at our hospital 2 years after its introduction...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-019-04201-7
更新日期:2020-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Delays in receiving obstetric care during labor contribute to high rates of maternal morbidity in sub-Saharan Africa. This exploratory study was conducted to identify important delays experienced during the development and subsequent repair of obstetric fistula in northern Tanzania. METHODS...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3416-2
更新日期:2018-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Minimally invasive sacral colpopexy has increased over the past decade, with many senior physicians adopting this new skill set. However, skill acquisition at an academic institution in the presence of postgraduate learners is not well described. This manuscript outlines the introduction of ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2085-z
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To evaluate factors for vesicovaginal fistula (VVF) formation following incidental cystotomies during benign hysterectomies. METHODS:Hysterectomies performed at two university centers between January 1, 2000 and December 31, 2008 were reviewed. Demographic and operative data were abstracted...
journal_title:International urogynecology journal
pub_type: 杂志文章,多中心研究
doi:10.1007/s00192-011-1375-6
更新日期:2011-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to identify risk factors for postpartum anatomic pelvic organ prolapse (aPOP) by comparing women with and without aPOP at 6 weeks postpartum with regard to pelvic floor measurements antepartum and obstetrical characteristics. METHODS:We carried out a prospective observatio...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3650-2
更新日期:2019-03-01 00:00:00
abstract::Leiomyomas of the external genitalia are uncommon soft tissue tumors. We report the case of a 47-year-old woman with perineal leiomyomas mimicking Bartholin's gland mass according to the preoperative magnetic resonance imaging (MRI) findings. Leiomyomas in the vulvar region should be differentiated from complicated Ba...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-009-0998-3
更新日期:2010-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Lower tract urinary symptoms are underestimated by women as well as health professionals. The objective of this study was to evaluate the behavior of adult women with urinary incontinence and overactive bladder symptoms in seeking medical treatment. METHODS:Two hundred ninety-two women betw...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1352-5
更新日期:2011-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective of this study was to investigate complications, urinary incontinence symptoms, and overall satisfaction in patients undergoing the tension-free vaginal tape-SECUR (TVT-S) for stress urinary incontinence (SUI). METHODS:We reviewed consecutive patients treated with TVT-S between...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1114-4
更新日期:2010-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Rectopexy and sacrocolpopexy can be performed concurrently to treat rectal and vaginal prolapse. We hypothesized that concurrent procedures might be associated with more complications than rectopexy and sacrocolpopexy alone. METHODS:Patients undergoing laparoscopic sacrocolpopexy or rectope...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3699-y
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to compare the results of repair of isolated, recurrent, posterior vaginal wall prolapse using standard posterior colporrhaphy versus non-absorbable polypropylene mesh in a routine health care setting. METHODS:This cohort study was based on prospectively collected ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-03856-y
更新日期:2019-10-01 00:00:00