Abstract:
INTRODUCTION AND HYPOTHESIS:This study assessed the safety and efficacy of vaginal extraperitoneal uterosacral ligament suspension (VEULS) with anterior overlay mesh versus sacrocolpopexy (SCP) for posthysterectomy vault prolapse. METHODS:This was a multicenter randomized trial of women with posthysterectomy vault prolapse stage >2 according to the Pelvic Organ Prolapse Quantification (POP-Q) system. Primary outcome was a composite of no vaginal bulge symptoms, no anatomical recurrence in the anterior or apical compartment at or beyond the hymenal ring, and no surgical retreatment for prolapse 12 months postsurgery. Secondary outcomes were peri- and postoperative complications, changes in prolapse, and urogenital and sexual symptoms at 12, 24, and 48 months based on the Pelvic Floor Distress Inventory (PFDI)-20. RESULTS:Between 2006 and 2011, 82 eligible women were randomized: 39 received VEULS and 43 received SCP. Primary composite outcome at 12 months for success was 41% for VEULS and 65% for SCP [odds ratio (OR 2.68, p = 0.03)]. Perioperative complications were more common in the SCP group. C-point was higher for SCP (-6.0 VEULS vs -8.0 SCP, p = 0.005) and total vaginal length (TVL) was longer for SCP (8.0 VEULS vs 9.0 SCP, p = 0.05). Cumulative mesh exposure rate at 4 years was similar between the uterosacral [4/39 (10.3%)] and sacrocolpopexy [4/43 (9.3%)] groups, bearing in mind that not all patients were examined at 4 years. Subjective outcomes derived from three domains of the PFDI-20 were similar at 12, 24, 48 months. Postoperative Pelvic Organ Prolapse Distress Inventory (POPDI) score improved similarly for both groups at all timepoints, with the minimally important difference of at least 21 reached for both groups. CONCLUSIONS:Composite outcome of success was better for SCP at 12 months, but subjective outcomes for prolapse at all timepoints over 4 years for VEULS and SCP were not significantly different.
journal_name
Int Urogynecol Jjournal_title
International urogynecology journalauthors
Ow LL,Lim YN,Lee J,Murray C,Thomas E,Leitch A,Rosamilia A,Dwyer PLdoi
10.1007/s00192-018-3687-2subject
Has Abstractpub_date
2018-11-01 00:00:00pages
1607-1614issue
11eissn
0937-3462issn
1433-3023pii
10.1007/s00192-018-3687-2journal_volume
29pub_type
杂志文章,多中心研究,随机对照试验abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to compare pelvic floor muscle strength (PFMS) and the prevalence of urinary incontinence (UI) and pelvic organ prolapse(POP) in women with and without diastasis recti abdominis (DRA) at 6-8 weeks postpartum. METHODS:Three hundred and ten women underwent routine ex...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-04005-9
更新日期:2020-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We aimed to compare the outcomes of native tissue vs. biological graft-augmented repair in the posterior compartment. We hypothesized that the addition of graft would result in superior anatomic and functional outcomes. METHODS:A retrospective review of posterior repairs between 2001 and 20...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1607-9
更新日期:2012-05-01 00:00:00
abstract::Clinical manifestations of vesicouterine fistulas, a rare complication of cesarean section, include amenorrhea and cyclic hematuria (menouria) without urinary incontinence, a triad collectively known as "Youssef's syndrome." Fistulas affecting the uterus usually reside above the isthmus or at the cervix and have a dis...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1849-1
更新日期:2013-04-01 00:00:00
abstract::Laparoscopic ventral mesh rectopexy (VMR) has become a popular surgical technique for treating women with full-thickness rectal prolapse with a low recurrence rate, as demonstrated by several studies. In addition, it is increasingly applied to female patients with obstructive defecation syndrome (ODS) caused by intuss...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3378-4
更新日期:2017-07-01 00:00:00
abstract:INTRODUCTION:InTone(TM) (InControl Medical) is a nonimplanted vaginal device providing biofeedback and electrical stimulation of pelvic floor muscles. The purpose of this study was to assess its efficacy and usability for treating urinary incontinence (UI). METHODS:Women with UI (stress, urge, mixed) were recruited fo...
journal_title:International urogynecology journal
pub_type: 临床试验,杂志文章
doi:10.1007/s00192-014-2476-9
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to compare the results of repair of isolated, recurrent, posterior vaginal wall prolapse using standard posterior colporrhaphy versus non-absorbable polypropylene mesh in a routine health care setting. METHODS:This cohort study was based on prospectively collected ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-03856-y
更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The protocol and analysis methods for the Defining Mechanisms of Anterior Vaginal Wall Descent (DEMAND) study are presented. DEMAND was designed to identify mechanisms and contributors of prolapse recurrence after two transvaginal apical suspension procedures for uterovaginal prolapse. METH...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04511-1
更新日期:2020-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The primary objective of this study was to compare outcomes of absorbable and permanent suture for apical support with high uterosacral ligament vaginal vault suspension (HUSLS). The secondary objective was to investigate the rate of suture erosion. METHODS:This was a retrospective study of...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1708-0
更新日期:2012-07-01 00:00:00
abstract::A damaged sphincteric unit or support system, unstable urethral deformability or damaged sensory innervation are all potential causes of a dysfunctional urethral sphincter. With the current improvement in pharmacological targets and urodynamic understanding, studies have begun quantifying individual structures and the...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-019-04104-7
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective of the study was to identify reasons why women declined participation in a pilot randomised controlled trial (RCT) comparing tension-free vaginal tape (TVT) under general anaesthetic (GA) with single incision sling (SIS) under local anaesthetic (LA). These data would inform the...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1967-9
更新日期:2013-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Pelvic organ prolapse (POP) commonly presents with a "vaginal lump or bulge" and/or a "dragging sensation." The first symptom correlates strongly with clinical and imaging data. However, a "dragging sensation" may be less specific. Hence, we investigated the predictive value of both symptoms...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3410-8
更新日期:2018-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:With the increasingly extensive application of epidural analgesia, its effect on pelvic floor function outcomes has received growing attention. The aim of the study is to determine the possible effect of epidural analgesia on pelvic floor muscle (PFM) endurance and strength and the prevalenc...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-04176-5
更新日期:2020-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Hyperandrogenism in women with polycystic ovary syndrome (PCOS) could increase muscle mass and thereby pelvic floor muscle (PFM) strength, reducing the risk of urinary incontinence (UI). The aim of the present study was to assess PFM strength and UI among hyperandrogenic women with PCOS and ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2095-x
更新日期:2013-10-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Modern classifications of pelvic floor movements are based on pelvic floor assessment in a static midsagittal plane. This study presents a new and potentially useful 3D noninvasive tool for studying pelvic floor mobility in women with pelvic organ prolapse (POP). MATERIALS AND METHODS:Thirt...
journal_title:International urogynecology journal
pub_type: 临床试验,杂志文章
doi:10.1007/s00192-016-2948-1
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Ongoing debate exists about whether the rectovaginal septum (Denonvilliers' fascia) is myth or reality. This study evaluates magnetic resonance images (MRI) of women with Müllerian agenesis for the presence of fascial layers between the rectum and the bladder to test the hypothesis that this...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2214-8
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the study was to assess the interobserver and intraobserver reliability of translabial 3D ultrasound imaging of the urethral sphincter in non-pregnant nulliparous asymptomatic women. METHODS:A study using a 3D translabial ultrasound on thirty-seven women was performed. Urethral s...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1669-3
更新日期:2012-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To evaluate the efficacy of double-J stenting as an initial procedure to manage ureteral injuries detected late after gynecological surgery. METHODS:Eight patients whom the insertion of double-J stent was done primarily were evaluated. Medical records were investigated retrospectively. RES...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-009-1092-6
更新日期:2010-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the study was to evaluate the subjective outcome between 1 and 5 years after tension-free vaginal tape (TVT) operation and the need for follow-up. METHODS:A prospective questionnaire study was performed including questions about incontinence, urinary tract infection, emptying pro...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1601-2
更新日期:2012-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to evaluate urinary symptoms and urodynamic diagnoses in women following repair of obstetric fistula of the lower urinary tract. METHODS:Women with previous genital tract fistula and ongoing urinary symptoms were evaluated at the Addis Ababa Fistula Hospital. The w...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1948-z
更新日期:2013-06-01 00:00:00
abstract::The concept of genitourinary syndrome of menopause (GSM) was recently introduced and has been gaining widespread use. While some justifications for its introduction are straightforward, others may be questionable. Numerous unspecific symptoms and signs were included in the definition of the syndrome, but the minimum n...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-017-3295-6
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to identify risk factors for postpartum anatomic pelvic organ prolapse (aPOP) by comparing women with and without aPOP at 6 weeks postpartum with regard to pelvic floor measurements antepartum and obstetrical characteristics. METHODS:We carried out a prospective observatio...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3650-2
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:A great variety of conservative and surgical procedures to correct vaginal vault prolapse have been reported. The aim of this study was to describe practice pattern variation-the difference in care that cannot be explained by the underlying medical condition-among Dutch gynecologists regardi...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3832-y
更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Management of stress urinary incontinence (SUI) with intravaginal devices is an alternative to surgical management, but data of a high level of evidence remain scarce. Our goal was to assess efficacy, tolerance, and acceptability of the 75NC007 intravaginal device for SUI management. METHOD...
journal_title:International urogynecology journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00192-012-1814-z
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim was to develop a nomogram based on clinical and surgical factors to predict the likelihood of voiding dysfunction after surgery for deep endometriosis. METHODS:This was a retrospective study of 789 patients (training set) who underwent surgery for deep endometriosis with colorectal ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04428-9
更新日期:2020-07-11 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We report 2-year data on the effectiveness and safety of the MiniArc single-incision sling in women with stress urinary incontinence. METHODS:This multi-center, prospective, single-arm, industry-sponsored study measured the effectiveness of the MiniArc sling via quantitative (cough stress t...
journal_title:International urogynecology journal
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s00192-012-1734-y
更新日期:2012-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Urinary tract infections (UTIs) are common with indwelling catheter use. Our primary aim was to compare UTI rates in women sent home after surgery with continuous bladder drainage versus a urinary catheter valve. METHODS:This was a non-inferiority prospective randomized controlled study bet...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04436-9
更新日期:2020-07-18 00:00:00
abstract::A 46-year-old white female underwent a left hemipelvectomy for chondrosarcoma. She presented with total incontinence and a bulging vaginal mass. Exam confirmed complete transurethral bladder eversion that was addressed with transvaginal multilayer bladder neck closure and suprapubic tube placement. Eventually she unde...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-009-0950-6
更新日期:2010-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the study was to evaluate the predictors and reasons for help-seeking behavior among women with urinary incontinence (UI) in Germany and Denmark. METHODS:This international postal survey was conducted in 2014. In each country, 4,000 women of at least 18 years of age were randomly...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3434-0
更新日期:2018-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Depression is more common in patients with urinary incontinence (UI). Drug or rehabilitation therapy have been shown to be effective in reducing urgency UI (UUI) symptoms, but whether these treatments can ameliorate the negative impact of UUI on the psychological aspects of quality of life i...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-013-2116-9
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The vagina and surrounding structures have been shown to remodel during pregnancy. Our objective was to characterize the biomechanical properties of the vagina in the rodent model in vivo utilizing three-dimensional (3D) ultrasound. METHODS:The vagina was visualized by ultrasound after dist...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2313-6
更新日期:2014-07-01 00:00:00