Jitter analysis with concentric needle electrodes.

abstract：:The CD27(+) IgD(+) B cell population, known as IgM memory, reduces with age. It is thought that this population is responsible for pneumococcal polysaccharide T-independent responses, and that the age-related reduction might be partially responsible for the increased susceptibility of older people to bacterial pathoge...

journal_title：Annals of the New York Academy of Sciences

authors： Martin V,Wu YC,Kipling D,Dunn-Walters DK

更新日期：2015-12-01 00:00:00

abstract：:The aim of this prospective study was to assess the prevalence of antiphospholipid antibodies (aPL) in women who had undergone in vitro fertilization (IVF) and the relationship between aPL and IVF outcome. A total of 101 infertile women with at least three unsuccessful IVF attempts were consecutively included in this ...

journal_title：Annals of the New York Academy of Sciences

authors： Sanmarco M,Bardin N,Camoin L,Beziane A,Dignat-George F,Gamerre M,Porcu G

更新日期：2007-06-01 00:00:00

abstract：:Every day billions of cells die in our bodies to eliminate those that are harmful, useless, or senescent. The process can be divided into two steps: cell dying and cell clearance. In the first step, death machinery is activated in the cells and quickly kills them. During the second step, dead cells are engulfed by pha...

journal_title：Annals of the New York Academy of Sciences

authors： Nagata S

更新日期：2010-10-01 00:00:00

abstract：:In rats, arginine vasopressin augments bradycardia associated with baroreflex activation. We investigated whether modulation of peripheral cardiac parasympathetic nerve function by AVP may play a role in this effect. To accomplish this we utilized an in vivo model with which we previously demonstrated both adrenergic ...

journal_title：Annals of the New York Academy of Sciences

authors： Pardini BJ,Lund DD,Schmid PG

更新日期：1993-07-22 00:00:00

abstract：:On the basis of evidence just reviewed, the hormonal requirements during IVM of mammalian oocytes for fertilization and developmental competence may be summarized as follows: 1. Nuclear maturation occurs "spontaneously," without follicular factors or hormones, in all mammalian species. 2. Cumulus cells are necessary d...

journal_title：Annals of the New York Academy of Sciences

authors： Armstrong DT,Zhang X,Vanderhyden BC,Khamsi F

更新日期：1991-01-01 00:00:00

abstract：:Most anticancer treatments such as chemo- and radiotherapy induce DNA damage and apoptosis in normal cells. The aim of this study was to assess the induction of single and double DNA strand breaks (ssb and dsb, respectively) and apoptosis in normal human lymphocytes and rat thymocytes subjected to the action of H2O2, ...

journal_title：Annals of the New York Academy of Sciences

authors： Benítez-Bribiesca L,Sánchez-Suárez P

更新日期：1999-01-01 00:00:00

abstract：:To test whether the development of emotional resilience is a function of sensitive caregiving and child negative affect, we tested the joint contributions of 7-month maternal sensitivity and infant negative affect to the prediction of 33-month emotional resilience across the first 3 years of life. The aims of this stu...

journal_title：Annals of the New York Academy of Sciences

authors： Conway AM,McDonough SC

更新日期：2006-12-01 00:00:00

abstract：:Photochemical smog is caused by a free-radical chain mechanism which converts NO to NO2. The NO2 further reacts to produce ozone, nitric acid, and peracylnitrates. This chain mechanism can be inhibited by suitable free-radical scavengers. The chemistry and toxicology of one such free-radical scavenger, diethylhydroxyl...

journal_title：Annals of the New York Academy of Sciences

authors： Heicklen J

更新日期：1987-01-01 00:00:00

abstract：:The loss of mucus coat continuity and apoptosis have been shown in Helicobacter pylori (H. pylori)-infected gastric tissues. Blockade of p38 mitogen-activated kinase (MAPK) produced reversal in the LPS-induced reduction in mucin synthesis and apoptosis in gastric epithelial cells. This study investigates whether H. py...

journal_title：Annals of the New York Academy of Sciences

authors： Kim H,Seo JH,Kim KH

更新日期：2003-12-01 00:00:00

abstract：:Pulmonary sarcoidosis is a disease characterized by increased numbers of T lymphocytes within the alveolar structures and the consequent spontaneous release of a variety of mediators relevant to the pathogenesis of this disorder. This phenomenon is associated with a different expansion of the T cell subpopulations pre...

journal_title：Annals of the New York Academy of Sciences

authors： Rossi GA,Sacco O,Cosulich E,Balbi B,Risso A,Ravazzoni C

更新日期：1986-01-01 00:00:00

abstract：:Mounting evidence suggests that oxidative processes contribute to the pathogenesis of atherosclerosis and that antioxidants may represent a strategy to complement the lowering of lipids in the therapy of this disease. Although multiple molecular events have been identified in vitro and although it is tempting to ascri...

journal_title：Annals of the New York Academy of Sciences

authors： Sigal E,Laughton CW,Mulkins MA

更新日期：1994-04-18 00:00:00

abstract：:The human serum resistance-associated (SRA) gene was identified in 28 (80%) of the 35 T.b. rhodesiense trypanosomes from parasitologically confirmed sleeping sickness cases, using the primers designed by Radwanska and in 27 (77.1%) of the same 35 T.b. rhodesiense trypanosomes using the primers designed by Gibson. Howe...

journal_title：Annals of the New York Academy of Sciences

authors： Enyaru JC,Matovu E,Nerima B,Akol M,Sebikali C

更新日期：2006-10-01 00:00:00

abstract：:T1DM is a disease that affects pancreatic beta cells and results in severe insulin depletion. T1DM is a multigenic disease, and the strongest genetic association with this disease is shown by the genes in MHC class II, namely, DQA1 and DQB1. The other gene that has been implicated in susceptibility to T1DM is the MICA...

journal_title：Annals of the New York Academy of Sciences

authors： Nikitina-Zake L,Ghaderi M,Park Y,Babu S,Eisenbarth G,Sanjeevi CB

更新日期：2004-12-01 00:00:00

abstract：:In the frame of the free-radical hypothesis of aging and literature data on increased life span of mated animals, we evaluated brain, kidney, and liver lipid peroxidation in C57Bl/6J mice of various ages and compared lipid peroxidation activity in mated and non-mated mice of both genders. An aging-associated increase ...

journal_title：Annals of the New York Academy of Sciences

authors： Oxenkrug GF,Requintina PJ

更新日期：2003-05-01 00:00:00

abstract：:West Nile virus (WNV) caused disease outbreaks in Israel in the 1950s and the late 1970s. In 1998 an outbreak of WNV in goose farms and evidence of infection in dead migratory birds were reported. Consequently, human diagnostic services for WNV were resumed, including virus isolation, serology, and RT-PCR. Risk factor...

journal_title：Annals of the New York Academy of Sciences

authors： Bin H,Grossman Z,Pokamunski S,Malkinson M,Weiss L,Duvdevani P,Banet C,Weisman Y,Annis E,Gandaku D,Yahalom V,Hindyieh M,Shulman L,Mendelson E

更新日期：2001-12-01 00:00:00

abstract：:A triple genetic association between serum IgE levels, mast cell numbers, and susceptibility to oral tolerance was observed in mice genetically selected to extreme phenotypes of oral tolerance (susceptibility and resistance), suggesting a coadaptation of genes controlling these traits. ...

journal_title：Annals of the New York Academy of Sciences

authors： da Silva AC,Silva MF,Bianchi C,Ribeiro RC,Nóbrega A,Sant'anna O

更新日期：2004-12-01 00:00:00

abstract：:The liver is morphologically and functionally modulated by sex hormones. Long-term use of oral contraceptives (OCs) and anabolic androgenic steroids (AASs) can induce both benign (hemangioma, adenoma, and focal nodular hyperplasia [FNH]) and malignant (hepatocellular carcinoma [HCC]) hepatocellular tumors. Hepatic ade...

journal_title：Annals of the New York Academy of Sciences

authors： Giannitrapani L,Soresi M,La Spada E,Cervello M,D'Alessandro N,Montalto G

更新日期：2006-11-01 00:00:00

abstract：:Long-lived proteins undergo age-related postsynthetic modifications by glycation and advanced glycation end products (AGEs), which destabilize them by altering their conformation and charge. It was accidentally discovered that ornithine (orn) increased with age in acid hydrolyzates of human skin collagen and lens crys...

journal_title：Annals of the New York Academy of Sciences

authors： Sell DR,Monnier VM

更新日期：2005-06-01 00:00:00

abstract：:Cardiac tissue engineering promises to revolutionize the treatment of patients with end-stage heart failure and provide new solutions to the serious problem of heart donor shortage. By its broad definition, tissue engineering involves the construction of tissue equivalents from donor cells seeded within three-dimensio...

journal_title：Annals of the New York Academy of Sciences

authors： Leor J,Cohen S

更新日期：2004-05-01 00:00:00

abstract：:Heart disease is the leading cause of death in the industrialized world. This is partially attributed to the inability of cardiomyocytes to divide in a significant manner, and therefore the heart responds to injury through scar formation. One of the challenges of modern medicine is to develop novel therapeutic strateg...

journal_title：Annals of the New York Academy of Sciences

authors： Bolli P,Chaudhry HW

更新日期：2010-11-01 00:00:00

abstract：:Mass spectrometric analysis of the low-molecular-weight (LMW) range of the serum/plasma proteome is revealing the existence of large numbers of previously unknown peptides and protein fragments, predicted to be derived from circulating low-abundance proteins. While genomics and proteomics are the primary discovery res...

journal_title：Annals of the New York Academy of Sciences

authors： Byrum S,Montgomery CO,Nicholas RW,Suva LJ

更新日期：2010-03-01 00:00:00

abstract：:The available evidence suggests that plasma leakage in dengue hemorrhagic fever is caused by the action of circulating mediators on the vascular endothelium, and that the host immune response is a critical determinant of this response. We have been exploring the role of dengue virus-specific T lymphocytes in the immun...

journal_title：Annals of the New York Academy of Sciences

authors： Rothman AL

更新日期：2009-09-01 00:00:00

abstract：:Previous research on development of the Xenopus olfactory bulb from our laboratory has shown that mitral cells begin to differentiate after olfactory axons make contact with the olfactory bulb, and the number of olfactory axons is correlated with the number of mitral cells throughout development. In embryos, removal o...

journal_title：Annals of the New York Academy of Sciences

authors： Burd GD,Sein V

更新日期：1998-11-30 00:00:00

abstract：:In biochemical and immunocytochemical comparisons of adhering junctions of different epithelia, we have observed differences in molecular composition not only between the intermediate filament-attached desmosomes and the actin filaments-anchoring adherens junctions but also between desmosomes of different tissues and ...

journal_title：Annals of the New York Academy of Sciences

authors： Borrmann CM,Mertens C,Schmidt A,Langbein L,Kuhn C,Franke WW

更新日期：2000-01-01 00:00:00

abstract：:The primate orbitofrontal cortex (OFC) is often treated as a single entity, but architectonic and connectional neuroanatomy indicate that it has distinguishable parts. Nevertheless, few studies have attempted to dissociate the functions of its subregions. Here we review findings from recent neuropsychological and neur...

journal_title：Annals of the New York Academy of Sciences

authors： Rudebeck PH,Murray EA

更新日期：2011-12-01 00:00:00

abstract：:The monoaminergic and cholinergic systems are implicated in different forms of behavioral arousal that can be dissected in terms of their forebrain targets and the nature of the behavioral processes they modulate in distinct regions. Thus, evidence in rats with selective neurochemical manipulations tested behaviorally...

journal_title：Annals of the New York Academy of Sciences

authors： Robbins TW,Granon S,Muir JL,Durantou F,Harrison A,Everitt BJ

更新日期：1998-06-21 00:00:00

abstract：:In natural tissues, cells form multiple attachment sites to their extracellular matrix. By means of those attachments, cells deform as the tissue deforms in response to the natural mechanical stresses and strains that the tissue must sustain during function. These mechanical forces are the energy input that instruct t...

journal_title：Annals of the New York Academy of Sciences

authors： Urry DW,Pattanaik A

更新日期：1997-12-31 00:00:00

abstract：:A cholinergic hypofunction in Alzheimer's disease (AD) may lead to formation of beta-amyloids that might impair the coupling of M1 muscarinic ACh receptors (mAChRs) with G proteins. This disruption in coupling can lead to decreased signal transduction, to a reduction in levels of trophic amyloid precursor proteins (AP...

journal_title：Annals of the New York Academy of Sciences

authors： Fisher A,Michaelson DM,Brandeis R,Haring R,Chapman S,Pittel Z

更新日期：2000-01-01 00:00:00

abstract：:Most of the plasma suppressive activity was associated with alpha 2M in both normal subjects and cancer patients. alpha 2M binding to physiological levels of proteases was associated with an increase in the ability to suppress lymphocyte reactivity in the TEEM test. alpha 2M binding to proteases released a peptide tha...

journal_title：Annals of the New York Academy of Sciences

authors： Alomran A,Shenton BK,Donnelly PK,Francis DM,Proud G,Taylor RM

更新日期：1983-01-01 00:00:00

abstract：:The sexual quality of adult song is the result of genetic and epigenetic mechanisms shaping the neural song system throughout life. Genetic brain-intrinsic mechanisms determine the neuron pools that develop into forebrain song control areas independent of gonadal steroid hormones, androgens and estrogens. One fate of ...

journal_title：Annals of the New York Academy of Sciences

authors： Gahr M

更新日期：2004-06-01 00:00:00