当前位置： SCI文献检索 > Journal of Cardiology期刊下所有文献 > Serum malondialdehyde-modified low-density lipoprotein levels on admission predict prognosis in patients with acute coronary syndrome undergoing percutaneous coronary intervention.

Serum malondialdehyde-modified low-density lipoprotein levels on admission predict prognosis in patients with acute coronary syndrome undergoing percutaneous coronary intervention.

Abstract：

BACKGROUND:Malondialdehyde-modified low-density lipoprotein (MDA-LDL) is a predictive marker of cardiovascular events in patients with stable angina pectoris. However, little is known about this marker in patients with acute coronary syndrome (ACS). We investigated the prognostic relevance of MDA-LDL to cardiovascular outcomes in patients with ACS. METHODS:A total of 370 consecutive patients with ACS who underwent primary percutaneous coronary intervention (PCI) were enrolled from October 2009 to September 2014 at Mitoyo General Hospital. Serum MDA-LDL levels were measured at admission. The patients were divided into three tertile groups according to serum MDA-LDL levels. The primary outcomes were cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, revascularization, and heart failure requiring hospital admission. RESULTS:MDA-LDL levels in patients with acute myocardial infarction were significantly greater than those in patients with unstable angina pectoris (mean±standard deviation: 133±48U/L vs. 157±69U/L, p=0.001). During follow-up [472 (195-920) days], 82 (22%) events occurred. Kaplan-Meier analysis showed that patients in the highest MDA-LDL tertile had the worst prognosis (log-rank, p<0.001). Cox regression analysis showed that serum MDA-LDL levels were an independent predictor of cardiovascular events after PCI in patients with ACS, even after adjustment for age, sex, body mass index, conventional cardiovascular risk factors, other lipid biomarkers, statin use on admission, cardiac biomarkers, and presence or absence of multivessel disease (hazard ratio: 1.80 per 1 standard deviation U/L increase, 95% confidence interval: 1.07-3.16, p=0.027). CONCLUSION:Serum MDA-LDL levels on admission are a significant prognostic marker in patients with ACS who undergo successful PCI.

journal_name

J Cardiol

journal_title

Journal of cardiology

authors

Amioka N,Miyoshi T,Otsuka H,Yamada D,Takaishi A,Ueeda M,Hirohata S,Ito H

doi

10.1016/j.jjcc.2019.02.012

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

258-266

issue

3

eissn

0914-5087

issn

1876-4738

pii

S0914-5087(19)30051-6

journal_volume

74

pub_type

杂志文章

相关文献

Journal of Cardiology文献大全
  • Coronary artery spasm--clinical features, diagnosis, pathogenesis, and treatment.

    abstract：:Coronary (artery) spasm plays an important role in the pathogenesis of ischemic heart disease, including stable angina, unstable angina, myocardial infarction, and sudden death. The prevalence of coronary spasm differs among populations, is higher in Japan and Korea than in the Western countries probably due to geneti...

    journal_title：Journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jjcc.2008.01.001

    authors： Yasue H,Nakagawa H,Itoh T,Harada E,Mizuno Y

    更新日期：2008-02-01 00:00:00

  • Sodium-Glucose Cotransporter-2 inhibitors are potential therapeutic agents for treatment of non-diabetic heart failure patients.

    abstract：:Despite recent developments in various therapies, heart failure remains a leading cause of morbidity and mortality worldwide. New pharmacological approaches are therefore needed to improve the outcomes of patients with heart failure. Diabetes mellitus is an important risk factor for heart failure, but until recently t...

    journal_title：Journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jjcc.2020.03.009

    authors： Nakagawa Y,Kuwahara K

    更新日期：2020-08-01 00:00:00

  • Pentraxin 3 as a biomarker for acute coronary syndrome: comparison with biomarkers for cardiac damage.

    abstract：BACKGROUND:Pentraxin 3 (PTX3) is increased in circulating blood during the acute stage of acute coronary syndrome (ACS). Therefore, we compared diagnostic values of PTX3 for ACS with those of biomarkers for myocardial damage, such as troponin T (TnT) and heart-type fatty acid binding protein (H-FABP). METHODS AND RESU...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2011.03.006

    authors： Kume N,Mitsuoka H,Hayashida K,Tanaka M

    更新日期：2011-07-01 00:00:00

  • Rationale and design of the NAGOYA HEART Study: comparison between valsartan and amlodipine regarding morbidity and mortality in patients with hypertension and glucose intolerance.

    abstract：BACKGROUND:Inhibitors of the renin angiotensin system are recommended as the first-line medications for diabetic hypertensive patients. However, there is less evidence supporting this recommendation especially among East Asians, a population with a unique distribution of cardiovascular disease compared to the Western p...

    journal_title：Journal of cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jjcc.2010.03.004

    authors： Matsushita K,Muramatsu T,Kondo T,Maeda K,Shintani S,Murohara T,NAGOYA HEART Study Group.

    更新日期：2010-07-01 00:00:00

  • Gender differences in the association between serum uric acid and prognosis in patients with acute coronary syndrome.

    abstract：BACKGROUND:Increased levels of uric acid (UA) have been associated with cardiovascular disease. This association is generally stronger in women than men. However, gender differences in the prognostic value of UA in patients with acute coronary syndrome (ACS) are unknown. We investigated gender differences in the relati...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2015.05.009

    authors： Kawabe M,Sato A,Hoshi T,Sakai S,Hiraya D,Watabe H,Kakefuda Y,Ishibashi M,Abe D,Takeyasu N,Aonuma K

    更新日期：2016-02-01 00:00:00

  • [Infarct size related to the distribution and site of coronary artery lesions studied by the unfolded map technique using single photon emission computed tomography].

    abstract：:To assess the relative importance of the anatomical characteristics of the coronary artery distribution and the sites of the arterial stenoses in relation to infarct size, 21 patients with old myocardial infarction and angiographically-proven 90% or greater stenoses (AHA classification) of one of the major coronary ar...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Kamihata H,Kurimoto T,Shimada T,Karakawa M,Matsuura T,Ogura E,Hata T,Hamaguchi Y,Inada M,Nishiyama Y

    更新日期：1988-03-01 00:00:00

  • Factors affecting in-hospital mortality and likelihood of undergoing surgical resection in patients with primary cardiac tumors.

    abstract：BACKGROUND:Previous studies on primary cardiac tumors were mainly based on small case series collected from a limited number of institutions. Contemporary data of patients with primary cardiac tumors treated with or without surgery in a nationwide clinical setting are limited. METHODS:Using the Diagnosis Procedure Com...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2016.05.008

    authors： Isogai T,Yasunaga H,Matsui H,Tanaka H,Hisagi M,Fushimi K

    更新日期：2017-01-01 00:00:00

  • [Concentric left ventricular hypertrophy in patients with aortic regurgitation].

    abstract：:Chronic aortic regurgitation (AR) is a disease incorporating volume overload of the left ventricle (LV) which is characterized by hyperactive left ventricular dilatation (LVD). However, we have encountered several patients who had concentric LV hypertrophy (LVH) instead of LVD. We therefore studied 50 consecutive pati...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Nishi H,Imawatari R,Chiba M,Koga Y,Toshima H

    更新日期：1989-12-01 00:00:00

  • Diagnostic value of automated quantification of nuclear cardiology in Japanese patients with single vessel coronary artery disease: comparison between Japanese and American normal databases.

    abstract：BACKGROUND:The Japanese diagnostic assessment of nuclear cardiology has usually been based on semi-quantitative visual analyses but not on automated quantification with a total perfusion deficit (TPD). We, therefore, aimed to determine whether automated TPD quantification is useful to detect coronary artery disease (CA...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2013.04.001

    authors： Yoda S,Nakanishi K,Tano A,Hori Y,Suzuki Y,Matsumoto N,Hirayama A

    更新日期：2013-10-01 00:00:00

  • Arterial stiffness and arterial function in adult cyanotic patients with congenital heart disease.

    abstract：BACKGROUND:Mortality in cyanotic patients with congenital heart diseases (CHD) is high, mainly due to cardiovascular complications. It is known that endothelial dysfunction, increased arterial stiffness, and impaired vascular function have negative influence on cardiovascular prognosis. The aim of the study was to asse...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2016.09.003

    authors： Trojnarska O,Szczepaniak-Chicheł L,Gabriel M,Bartczak-Rutkowska A,Rupa-Matysek J,Tykarski A,Grajek S

    更新日期：2017-07-01 00:00:00

  • Comprehensive evaluation of the apex beat using 64-slice computed tomography: Impact of left ventricular mass and distance to chest wall.

    abstract：OBJECTIVES:Although physicians frequently perform palpation of the apex beat to evaluate left ventricular (LV) size and hypertrophy, the clinical significance of apex beat palpation is still unclear. The introduction of multislice computed tomography (MSCT) has enabled assessment not only of coronary stenoses but also ...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2009.11.008

    authors： Ehara S,Okuyama T,Shirai N,Oe H,Matsumura Y,Sugioka K,Itoh T,Otani K,Hozumi T,Yoshiyama M,Yoshikawa J

    更新日期：2010-03-01 00:00:00

  • Developmental origins of health and disease theory in cardiology.

    abstract：:Numerous epidemiological and animal studies disclosed that birth weight is inversely associated with the incidence of the lifestyle-related disorders in adult life, such as cardiovascular disease, diabetes, and /or chronic kidney disease. Lower birth weight occurs in numerous undesired intrauterine environments includ...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2020.02.003

    authors： Arima Y,Fukuoka H

    更新日期：2020-07-01 00:00:00

  • Efficacy and safety of bivalirudin in coronary artery disease patients with mild to moderate chronic kidney disease: Meta-analysis.

    abstract：BACKGROUND:Patients with chronic kidney disease (CKD) have elevated bleeding and ischemic outcomes. We aim to assess the short- and long-term efficacy and safety of bivalirudin compared to heparin plus glycoprotein IIb/IIIa inhibitors (GPIs) in coronary artery disease (CAD) patients with CKD. METHODS:Randomized trials...

    journal_title：Journal of cardiology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jjcc.2017.10.018

    authors： Zeng X,Lincoff AM,Schulz-Schüpke S,Steg PG,Elbez Y,Mehran R,Stone GW,McAndrew T,Lin J,Zhang X,Shi W,Lei H,Jing Z,Huang W

    更新日期：2018-05-01 00:00:00

  • The importance of serial cardiac troponin measurement for evaluating the response to immunosuppressive therapy for myocarditis.

    abstract：:A 71-year-old woman was admitted to our department because of acute myocarditis. She was ameliorated with conventional heart failure treatment, however she developed left ventricular dilatation and cardiac troponin T (cTnT) was elevated again to >1.0 ng/ml 6 month after the first admission. She was re-admitted because...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2008.05.002

    authors： Kadota S,Takeuchi Y,Izuhara M,Baba O,Shioji K,Uegaito T,Kadota E,Matsuda M

    更新日期：2008-10-01 00:00:00

  • [Hemodynamic sequelae following valve replacement in patients with aortic regurgitation].

    abstract：:Serial echocardiographic analyses of the left ventricle (LV) were performed in 61 patients with aortic regurgitation before, one-six months, and six years after aortic valve replacement (AVR). There was no significant difference in the preoperative hemodynamic and echocardiographic data between 54 survivors and six de...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Onishi S,Handa S,Ikeda F,Hosokawa M,Yoshino H,Ogawa S,Nakamura Y,Soma Y,Inoue T

    更新日期：1989-06-01 00:00:00

  • Combined surgery for ischemic cardiomyopathy: report of a case.

    abstract：:A 65-year-old female with catecholamine-dependent ischemic cardiomyopathy was admitted to our hospital. Preoperative examination revealed severe triple vessel coronary artery disease, severe mitral valve regurgitation and left ventricular (LV) dilatation associated with low ejection fraction. Coronary artery bypass gr...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2008.03.006

    authors： Ishikawa S,Ueda K,Kawasaki A,Neya K,Abe K,Suzuki H,Shirato H,Yamazaki E,Aoyagi Y

    更新日期：2008-08-01 00:00:00

  • Recovery of atrioventricular block following steroid therapy in patients with cardiac sarcoidosis.

    abstract：BACKGROUND:Atrioventricular (AV) block is one of the main clinical manifestations in patients with cardiac sarcoidosis (CS). Although steroid therapy is considered to be effective for AV block, the efficacy has not been demonstrated in detail. METHODS AND RESULTS:Fifteen CS patients presenting with advanced or complet...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2013.07.007

    authors： Yodogawa K,Seino Y,Shiomura R,Takahashi K,Tsuboi I,Uetake S,Hayashi H,Horie T,Iwasaki YK,Hayashi M,Miyauchi Y,Shimizu W

    更新日期：2013-11-01 00:00:00

  • [Clinical significance of additional ST segment elevation immediately after successful reperfusion in patients with anterior wall acute myocardial infarction].

    abstract：:The clinical significance of additional ST segment elevation immediately after reperfusion in acute myocardial infarction (AMI) is still unclear. The influence of additional ST elevation on myocardial damage was examined in 62 patients with first anterior AMI. All patients had coronary reflow (thrombolysis in myocardi...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Kosuge M,Kimura K,Ishikawa T,Nemoto T,Shimizu T,Mochida Y,Iwasawa Y,Sugiyama M,Kuji N,Miyazaki N,Tochikubo O,Ishii M

    更新日期：1996-07-01 00:00:00

  • Meta-analysis of transcatheter aortic valve implantation for bicuspid versus tricuspid aortic valves.

    abstract：BACKGROUND:We performed meta-analysis and meta-regression of transcatheter aortic valve implantation (TAVI) for the bicuspid aortic valve (B-AV) versus the tricuspid aortic valve (T-AV). METHODS:MEDLINE and EMBASE were searched through June 2018 using PubMed and OVID. We included comparative studies of TAVI patients w...

    journal_title：Journal of cardiology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jjcc.2019.03.018

    authors： Takagi H,Hari Y,Kawai N,Kuno T,Ando T,ALICE (All-Literature Investigation of Cardiovascular Evidence) Group.

    更新日期：2019-07-01 00:00:00

  • [Post-myocardial infarction ventricular aneurysm and intractable ventricular tachycardia supported by left ventricular assist device: a case report].

    abstract：:A 57-year-old man was admitted under a diagnosis of myocardial infarction. Cardiac catheterization revealed total occlusions of the right coronary artery and the left anterior descending artery, and ventriculography showed aneurysmal change in the anterior and septal segments. Circulatory support was introduced with i...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Ueno K,Konishi T,Fukata M,Okura K,Furukawa H,Shiba Y,Yumoto K,Tamaki T,Nogami A,Kato K

    更新日期：2004-05-01 00:00:00

  • Three-dimensional echocardiography by semi-automatic border detection in assessment of left ventricular volume and ejection fraction: comparison with magnetic resonance imaging.

    abstract：:The feasibility of three-dimensional echocardiographic reconstruction by semi-automatic border detection to assess left ventricular volume and function was investigated in a clinically applicable setting in 23 patients with various cardiac diseases and 7 normal volunteers. The commercial equipment permits digital acqu...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Iwase M,Kondo T,Hasegawa K,Kimura M,Matsuyama H,Watanabe Y,Hishida H

    更新日期：1997-08-01 00:00:00

  • [Health-related quality of life in Japanese patients with ischemic heart disease: a multicenter cooperative investigation assessed using SF-36].

    abstract：OBJECTIVES:To investigate the quality of life (QOL) of Japanese patients with ischemic heart disease. METHODS:The QOL data of 753 patients with chronic and stable ischemic heart disease was assessed using SF-36 Japanese version 1.2 and compared with Japanese national norms. Physical (PCS) and Mental Component Summary ...

    journal_title：Journal of cardiology

    pub_type： 杂志文章,多中心研究

    doi：

    authors： Nishiyama S,Momomura S,Ishiwata S,Daida H,Hara K,Nishimura S,Nakamura M,Yamashina A,Shirai T,Yutaro N,Yamazaki T,Research Group of Quality of Life for Ischemic Heart Disease.

    更新日期：2005-12-01 00:00:00

  • [Noninvasive evaluation of left ventricular function using new systolic time intervals obtained from continuous-wave Doppler echocardiography].

    abstract：:Left ventricular function was evaluated using parameters derived from the flow velocity waveforms at the ascending aorta as obtained at the suprasternal notch by continuous-wave Doppler echocardiography in 39 patients; 12 with chest pain but without coronary stenosis, eight with angina pectoris; and 19 with myocardial...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Ohte N,Nakano S,Hashimoto T,Narita H,Fujinami T

    更新日期：1990-01-01 00:00:00

  • [Venous flow velocity patterns and cardiac function studied by Doppler echocardiography].

    abstract：:To study the relations of central venous flow velocity (VFV) to cardiac pump function, hepatic venous flow velocity was recorded using Doppler echocardiography in six normal subjects and 47 patients with heart disease, of whom 28 had sinus rhythm and 19, atrial fibrillation. The area under the VFV profile during systo...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Himura Y,Kannagi T,Tanio H,Nakamura Y,Kumada T,Kawai C

    更新日期：1988-09-01 00:00:00

  • Minimal energy requirement for external cardioversion and catheter ablation for long-standing persistent atrial fibrillation.

    abstract：BACKGROUND:The minimal energy requirement (Emin) for electrical cardioversion (ECV) reflects the atrial substrate in patients with long-standing persistent atrial fibrillation (L-PeAF), but the relationship between EminECV and radiofrequency catheter ablation (RFCA) has not yet been studied. We hypothesize that EminECV...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jjcc.2016.02.014

    authors： Kim IS,Kim TH,Yang PS,Uhm JS,Joung B,Lee MH,Pak HN

    更新日期：2017-01-01 00:00:00

  • [Aorto-coronary bypass surgery for children with Kawasaki disease].

    abstract：:The results of aorto-coronary bypass surgery in 28 children with coronary artery lesions due to Kawasaki disease were evaluated. Ages at surgery ranged from one to 17 years, and the intervals from disease onset to surgery ranged from 2 months to 16.8 years. All patients were followed by selective coronary arteriograph...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Suzuki A,Kamiya T,Ono Y,Nakamura Y,Yagihara T

    更新日期：1991-01-01 00:00:00

  • Ultrasound attenuated coronary plaque as a risk factor for slow flow or no-reflow during percutaneous coronary intervention: a case report.

    abstract：:Slow flow or no-reflow is a serious complication during percutaneous coronary intervention (PCI), but little is known about the risk factors. A 64-year-old man underwent coronary angiography and PCI for stable angina. Pre-interventional intravascular ultrasound demonstrated an ultrasound attenuated coronary plaque, as...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Furuichi S,Itoh A,Ishibashi-Ueda H,Noguchi T,Miyawaki M,Nomura K,Arita Y,Otsuka M,Shindo T

    更新日期：2007-04-01 00:00:00

  • [Involvement of endothelin and prostanoids in coronary vasospasm].

    abstract：:The involvement of endothelin, an important endogenous vascular constrictor, and prostanoids in coronary vasospasm was evaluated in 14 patients with and 12 patients without coronary vasospasm who had normal coronary angiograms. Coronary vasospasm was defined as a total or subtotal occlusion or diffuse and intense cons...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Igarashi K,Horimoto M,Takenaka T

    更新日期：1993-01-01 00:00:00

  • [Clinical investigation of inhomogeneity of washout rate in dipyridamole stress thallium scintigraphy: implication of new parameter for the indication of coronary intervention].

    abstract：OBJECTIVES:The standard deviation of the washout rate in dipyridamole stress thallium-201 myocardial single photon emission computed tomography (SPECT) was correlated with the severity of coronary artery lesions and the viability of ischemic myocardium to provide a new quantitative parameter for judging indications for...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Arao M,Setsuta K,Seino Y,Takano T

    更新日期：2000-11-01 00:00:00

  • Risk factors and the effects of xamoterol in idiopathic dilated cardiomyopathy.

    abstract：:A long-term follow-up study was performed for 110 patients with idiopathic dilated cardiomyopathy (DCM) for 34 +/- 12 months (range 3-122 months). Thirteen patients died of heart failure, 15 of sudden death and one of non-cardiac death. The 3- and 5-year survival rates were 78 and 62%, respectively. The important fact...

    journal_title：Journal of cardiology

    pub_type： 杂志文章

    doi：

    authors： Watanabe K,Hirokawa Y,Suzuki K,Masani F,Otsuka H,Izumi T,Shibata A

    更新日期：1992-01-01 00:00:00