Abstract:
:Chronic aortic regurgitation (AR) is a disease incorporating volume overload of the left ventricle (LV) which is characterized by hyperactive left ventricular dilatation (LVD). However, we have encountered several patients who had concentric LV hypertrophy (LVH) instead of LVD. We therefore studied 50 consecutive patients with isolated AR but without aortic stenosis and found seven patients with concentric LVH having LV wall thickness (determined by summing ventricular septal and posterior wall thicknesses) exceeding 30 mm and LV diastolic diameters of less than 60 mm. These seven patients with AR and LVH were older (55 +/- 27 vs 42 +/- 11 years) and tended to have milder degree of AR, compared with the remaining 43 patients having AR and LVD. However, patients with AR and LVH did not differ from AR and LVD as to the cardiothoracic ratio, SV1 + RV5, T-waves, ejection fraction, operative findings of valvular morphology and underlying etiologies. In contrast, patients with AR and LVH presented higher systolic (196 +/- 41 vs 149 +/- 26 mmHg, p less than 0.01) and diastolic pressures (74 +/- 14 vs 51 +/- 13 mmHg, p less than 0.01) and higher systemic vascular resistance (1,854 +/- 399 vs 1,388 +/- 352 dyne.sec.cm-5, p less than 0.05) during catheterization than did those with AR and LVD. However, blood pressure at the time of admission was not different in the two groups. These observations indicate that concentric LVH is not rare among patients with AR, and that an association of pressure overload with volume overload of the LV, particularly during exercise or stress, may lead to concentric LVH, even in patients with chronic AR.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Nishi H,Imawatari R,Chiba M,Koga Y,Toshima Hsubject
Has Abstractpub_date
1989-12-01 00:00:00pages
1099-105issue
4eissn
0914-5087issn
1876-4738journal_volume
19pub_type
杂志文章abstract:BACKGROUND:Cardiac rehabilitation (CR) has numerous beneficial effects, including the modification of coronary risk factors and improvement of the prognosis, in patients with coronary artery disease (CAD). Limited data are available regarding the effects of CR on the physical status and risk factors in patients with me...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2009.01.004
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Based on the importance of left ventricular (LV) diastolic function in stratification of the cardiac prognosis in patients with systolic heart failure (SHF), we attempted to identify the prognostic impact of Doppler echocardiographic examinations and plasma B-type natriuretic peptide (BNP) concentration. ME...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2008.07.008
更新日期:2008-12-01 00:00:00
abstract::The clinical benefit of cholesterol-lowering treatment is unknown in the Japanese elderly in whom the prevalence of morbidity and mortality related to coronary artery disease are known to be low. To evaluate the efficacy of cholesterol-lowering treatment with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase i...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVES:To study the involvement of vasospasm as the trigger of acute myocardial infarction without significant stenosis, the circadian variation of the time of onset of acute myocardial infarction was compared with that of vasospastic angina without significant stenosis. METHODS:The subjects consisted of 3 groups,...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::A 67-year-old woman without history of heart disease was admitted with chest oppression. Her electrocardiogram (ECG) at the time of admission showed ST segment elevation in leads V2-V6. Cardiac ultrasound revealed severe hypokinesis in mid to apical portion of anterior wall. Emergent coronary angiography showed normal...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2008.06.008
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Puerarin is the most abundant isoflavonoid in kudzu root. It has been used to treat angina pectoris and myocardial infarction clinically. However, little is known about the effect of puerarin on cardiac hypertrophy. METHODS:Aortic banding (AB) was performed to induce cardiac hypertrophy in mice. Puerarin pr...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2013.06.008
更新日期:2014-01-01 00:00:00
abstract::To investigate the influence of atrioventricular asynchronous contraction on left and right ventricular performance, pulsed Doppler echocardiographic studies were performed in 10 patients who received permanent pacemaker (VVI mode), but without significant heart disease except for complete heart block. After setting t...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Although combination therapy for various cardiac conditions with dual antiplatelet therapy (aspirin and thienopyridine derivatives) and warfarin sodium has become increasingly popular, the safety and effectiveness of this aggressive treatment regimen remain unknown. METHODS AND RESULTS:We retrospectively en...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2009.12.014
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Early recognition of cardiac arrest is essential for increasing the likelihood of successful resuscitation. However, many factors could obstruct the recognition of cardiac arrest and delay the delivery of cardiopulmonary resuscitation and automated external defibrillator use. We have developed a new system u...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2020.11.006
更新日期:2020-11-23 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Intravenous myocardial contrast echocardiography is used clinically, but use in small animals has not been evaluated. The conditions for myocardial opacification and the feasibility of myocardial contrast echocardiography were examined in mice. METHODS:Closed chest mice were examined. The lef...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to identify a cut-off value to predict the resolution of incomplete-stent-apposition (ISA) after cobalt-chromium everolimus-eluting stent (CoCr-EES) implantation at early follow-up. BACKGROUND:To date, appropriate stent apposition at the acute period using intracoronary imaging ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.12.006
更新日期:2020-06-01 00:00:00
abstract::Vaccines are primarily used worldwide as a preventive medicine for infectious diseases and have recently been applied to cancer. We and others have developed therapeutic vaccines designed for cardiovascular diseases that are notably different from previous vaccines. In the case of cancer vaccines, a specific protein i...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jjcc.2017.01.010
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:To determine which improves clinical outcomes more, sutureless (including rapid-deployment) aortic valve replacement (AVR) or transcatheter aortic valve implantation (TAVI), we performed a meta-analysis of comparative studies. METHODS:MEDLINE and EMBASE were searched through June 2015 using Web-based search...
journal_title:Journal of cardiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.jjcc.2015.09.009
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Serum levels of lipoprotein (a) [Lp(a)] have been reported as a residual risk marker for adverse events in patients with coronary artery disease (CAD). However, the prognostic impact of Lp(a) on long-term clinical outcomes among diabetic patients on statin therapy after percutaneous coronary intervention (PC...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2020.01.013
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Leakage of Ca2+ from the sarcoplasmic reticulum (SR) is a critical contributing factor to heart failure pathophysiology. Therefore, reducing SR Ca2+ leaks may provide significant additive benefits when used in combination with conventional therapies. Dantrolene, a drug routinely used to treat malignant hyper...
journal_title:Journal of cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jjcc.2019.08.020
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Third-generation drug-eluting-stents (3rd DES) may improve coronary arterial healing and reduce neoatherosclerosis formation. We evaluated post-stent findings and subsequent vascular healing of 3rd DES by comparing to second-generation drug-eluting-stents (2nd DES) at intermediate-term follow-up using optica...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2020.05.013
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:Rapid mobilization and discharge following rapid acute phase reperfusion are recommended for elderly patients with acute myocardial infarction to achieve a better outcome and performance. The safety and efficacy of new and old treatment protocols were retrospectively compared for patients with acute myocardi...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-10-01 00:00:00
abstract::The influence of complete revascularization on long-term outcome of patients with multivessel coronary artery disease undergoing percutaneous transluminal coronary angioplasty (PTCA) was determined by analysis of 10-year survival in 167 consecutive patients treated at Juntendo University Hospital during 1984-1993. For...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::Crow-Fukase syndrome is a disease of plasma cell dyscrasia. Congestive heart failure is the biggest complication affecting the prognosis. A 57-year-old male was admitted with edema and low grade fever. Globe and stocking type polyneuropathy, increased levels of adrenocorticotropic hormone and thyroid-stimulating hormo...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:There have been no reviews regarding intravascular ultrasound (IVUS) catheter entrapment during percutaneous coronary intervention (PCI). This study investigated the incidence, retrieval methods, and outcomes of IVUS catheter stuck within implanted stents. METHODS:Between January 2015 and July 2018, a total...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.07.005
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Although an increased epicardial adipose tissue (EAT) volume around the left atrium (LA) is related to the atrial fibrillation (AF) burden, the role of EAT inflammation in AF is unclear. We investigated the association between AF and inflammation of the EAT around the LA. METHODS:We retrospectively identifi...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2015.11.005
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Anticoagulant therapy is used for preventing cerebral infarction in patients with non-valvular atrial fibrillation (NVAF). However, in clinical practice, many patients with NVAF are not prescribed oral anticoagulants (OACs). In this study, we retrospectively investigated the prescription status of OACs at th...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.11.002
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Missense mutations in KCNH2, a gene encoding the Kv11.1 channel, cause long QT syndrome (LQTS) type 2 primarily by disrupting the intracellular transport of Kv11.1 to the plasma membrane. The present study aimed to clarify the functional changes by two novel KCNH2 missense mutations. METHODS:We performed ge...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2017.10.004
更新日期:2018-04-01 00:00:00
abstract::Surgical indications for patients with ischemic heart disease are discussed from a physician's viewpoint. Among the subsets of this disease, surgical treatment is undoubtedly recommended for patients with serious complications following acute myocardial infarction (MI) such as cardiac rupture, interventricular septal ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
abstract::The correlation between the time-course changes in the serum concentration of myosin light chain 1 (ML-1) and left ventricular (LV) function was investigated in 37 patients with initial anterior acute myocardial infarction (AMI) after successful reperfusion. All patients were confirmed to have coronary arteries recana...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:The most prevalent and serious infection related to left ventricular assist devices (LVADs) is driveline infection (DLI). From 2014, we employed a revised surgical technique (triple tunnel method), which deployed a longer subfascial driveline (DL) route. METHODS AND PATIENTS:We retrospectively analyzed 34 p...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2018.04.003
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Objective nutritional indexes have been shown to predict prognoses in some clinical settings. We aimed to investigate the prognostic values of these indexes in patients undergoing transcatheter aortic valve implantation (TAVI). METHODS:We retrospectively analyzed 95 consecutive patients who underwent TAVI a...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.02.017
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Although eastern Asian countries are exposed to high levels of air pollution, the impact of long-term exposures to fine particulate matter (PM2.5) air pollution on all-cause and cardiovascular mortality is not well identified. We assessed the relationship between long-term PM2.5 exposure and all-cause/cardio...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.11.004
更新日期:2020-05-01 00:00:00
abstract::The significance of the early maximal negative T wave on electrocardiography was evaluated in 74 patients with initial acute anterior myocardial infarction (MI) admitted within 6 hours of onset. The relationship between the negative T wave and the severity of MI, as assessed by MI size and left ventricular dysfunction...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:The deleterious effect of renal impairment in non-valvular atrial fibrillation (AF) patients has recently been reported. We investigated the impact of moderate to severe renal impairment on long-term clinical outcomes in AF patients. METHODS:A total of 2126 AF patients were enrolled and divided into two gro...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2016.04.006
更新日期:2017-03-01 00:00:00