Abstract:
:The involvement of endothelin, an important endogenous vascular constrictor, and prostanoids in coronary vasospasm was evaluated in 14 patients with and 12 patients without coronary vasospasm who had normal coronary angiograms. Coronary vasospasm was defined as a total or subtotal occlusion or diffuse and intense constriction of the left coronary artery provoked by intracoronary acetylcholine administration and associated with electrocardiographic ischemic ST-segment shifts. Blood samples were taken from the left coronary ostium and the coronary sinus before and during coronary spasm. The blood concentrations of endothelin, 6-keto-PGF1 alpha, and thromboxane B2 were measured. Patients with and without coronary vasospasm demonstrated no significant changes in endothelin and thromboxane B2 concentrations in the coronary sinus blood, or in the difference between left coronary ostium and coronary sinus blood. Patients with coronary vasospasm had 6-keto-PGF1 alpha concentrations in the coronary sinus before and during coronary vasospasm of 133.6 +/- 32.5 and 179.4 +/- 46.7 pg/ml, respectively (p < 0.05), and the differences between coronary sinus and coronary ostium concentrations were -25.7 +/- 29.5 and 41.6 +/- 22.6 pg/ml, respectively (p < 0.05). Patients without coronary vasospasm showed no significant changes in 6-keto-PGF1 alpha concentration. Endothelin and thromboxane A2 are not involved in coronary vasospasm, while prostacyclin concentration rises during coronary vasospasm provoked by acetylcholine.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Igarashi K,Horimoto M,Takenaka Tsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
257-62issue
3eissn
0914-5087issn
1876-4738journal_volume
23pub_type
杂志文章abstract:OBJECTIVES:To assess the clinical significance of iodine-123 beta-methyl-p-iodophenyl-pentadecanoic acid(BMIPP) single photon emission computed tomography(SPECT), the predictive value of BMIPP imaging in patients with angina pectoris was evaluated. METHODS:One hundred seventy-four patients who underwent BMIPP imaging ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::A 90-year-old woman was admitted to a local clinic with fever, anorexia, and right lower abdominal pain on March 25, 2004. She was referred to our hospital for detailed examination of an abdominal aortic aneurysm on May 18. Computed tomography revealed an abdominal aortic aneurysm measuring 78mm in maximal diameter an...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:The outcome of percutaneous coronary intervention (PCI) has been reported to be poor in hemodialysis (HD) patients even in the drug-eluting stent era. We have reported relatively poor outcomes after sirolimus-eluting stent implantation in the OUCH study. METHODS:The OUCH-TL study is a prospective, non-rando...
journal_title:Journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jjcc.2015.03.008
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Despite the frequent use of spectral analysis of intravascular ultrasound radiofrequency data (VH(®) IVUS) in clinical studies, the assessment for reproducibility using this with high frequency IVUS remains unexplored. PURPOSE:The aim of this study was to examine the reproducibility of VH IVUS using 45-MHz ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2014.05.004
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:In Kawasaki disease (KD), it has been clinically and experimentally reported that post-inflammatory vascular remodeling would induce the development of arteriosclerosis or early onset of atherosclerosis in the future. The effects of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors on cont...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2010.06.006
更新日期:2010-09-01 00:00:00
abstract::A 51-year-old man was admitted for evaluation of palpitation and syncope. Electrocardiography showed right bundle branch block with ST segment elevation. Intravenous administration of pilsicainide(50 mg) converted the saddle-back type into coved type ST elevation. Ventricular fibrillation was induced with double extra...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:The standard deviation of the washout rate in dipyridamole stress thallium-201 myocardial single photon emission computed tomography (SPECT) was correlated with the severity of coronary artery lesions and the viability of ischemic myocardium to provide a new quantitative parameter for judging indications for...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:The relationship between ongoing myocardial damage and heart failure with preserved left ventricular systolic function (HF-PEF) is still unclear. To investigate this relationship, we measured the cardiac-specific cytosolic marker, heart-type fatty acid binding protein (H-FABP), and a myofibrillar component (...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2012.06.006
更新日期:2012-12-01 00:00:00
abstract::The influence of morphological and dynamic changes in the interventricular septum (IVS) on right ventricular (RV) and left ventricular (LV) fillings in cases of LV or RV pressure overload was evaluated. Using pulsed Doppler echocardiography, LV and RV inflow signals were recorded in 20 healthy subjects, in 36 cases of...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1987-12-01 00:00:00
abstract:BACKGROUND:Relative myocardial perfusion imaging can misdiagnose "balanced" ischemia caused by coronary artery disease (CAD). We assessed the feasibility of myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) using dynamic single-photon emission computed tomography (SPECT) with a cadmium-zinc-telluride (...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.09.006
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Although eastern Asian countries are exposed to high levels of air pollution, the impact of long-term exposures to fine particulate matter (PM2.5) air pollution on all-cause and cardiovascular mortality is not well identified. We assessed the relationship between long-term PM2.5 exposure and all-cause/cardio...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.11.004
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:We determined the effect of two-time inflation of the stent balloon on stent expansion and its responsible factor. METHODS:Subjects included 61 patients with de novo coronary artery lesions, in whom 12 sirolimus-eluting, 27 paclitaxel-eluting, and 22 other stents were deployed twice at identical inflation p...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2011.12.003
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:Serum malondialdehyde-modified low-density lipoprotein(MDA-LDL) was measured as a marker of oxidative stress, and the changes in serum MDA-LDL compared in patients with acute myocardial infarction and stable angina pectoris treated by percutaneous transluminal coronary angioplasty (PTCA). METHODS:Forty-one ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:There have been no reviews regarding intravascular ultrasound (IVUS) catheter entrapment during percutaneous coronary intervention (PCI). This study investigated the incidence, retrieval methods, and outcomes of IVUS catheter stuck within implanted stents. METHODS:Between January 2015 and July 2018, a total...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.07.005
更新日期:2020-02-01 00:00:00
abstract:AIMS:The effects of inotropic agents on left ventricular (LV) synchrony in heart failure patients are still unknown. The purpose of this study was to investigate the effects of dobutamine on LV mechanical dyssynchrony and LV systolic performance in patients with dilated cardiomyopathy (DCM) and a narrow QRS using real-...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2012.12.012
更新日期:2013-04-01 00:00:00
abstract::A 54-year-old man was admitted as an emergency following an episode of syncope and severe dyspnea. The clinical presentation and laboratory data strongly suggested pulmonary embolism, so intravenous thrombolytic therapy was performed. Immediately following the initiation of thrombolytic therapy, the patient experience...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract::Elevated levels of lipoprotein(a) [Lp(a)] have been associated with an increased risk of ischemic heart disease (IHD), and higher levels of Lp(a) are associated with lesions of significantly greater severity. We have examined Lp(a), total cholesterol (TC) and high density lipoprotein-cholesterol (HDL-C) levels in pati...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Assessment of deterioration of regional wall motion by echocardiography is not only subjective but also features difficulties with interobserver agreement. Progress in digital communication technology has made it possible to send video images from a distant location via the Internet. OBJECTIVES:The possibil...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2007-02-01 00:00:00
abstract::Despite significant advances in pharmacological treatments, pulmonary arterial hypertension remains an incurable disease with an unreasonably high morbidity and mortality. Although specific pharmacotherapies have shifted the survival curves of patients and improved exercise endurance as well as quality of life, it is ...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jjcc.2015.02.001
更新日期:2015-10-01 00:00:00
abstract::Slow flow or no-reflow is a serious complication during percutaneous coronary intervention (PCI), but little is known about the risk factors. A 64-year-old man underwent coronary angiography and PCI for stable angina. Pre-interventional intravascular ultrasound demonstrated an ultrasound attenuated coronary plaque, as...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Chronic kidney disease (CKD) is an evolving paradigm for the risk assessment of cardiovascular diseases. We hypothesized that an advanced stage of CKD may predict the presence of peripheral arterial disease (PAD). METHODS:Screening for PAD by an ankle-brachial pressure index (ABI) ≤0.9 was conducted in a co...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2015.01.011
更新日期:2015-11-01 00:00:00
abstract::Patients with myocardial infarction (MI) and triple vessel coronary disease generally have poor prognoses. However, it is not known whether there are particular angiographic variables associated with the poor prognosis in MI patients with triple vessel disease. The angiographic variables for poor prognosis were invest...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::Ischemic preconditioning is an attenuation of myocardial ischemia by repeated brief coronary occlusions observed during percutaneous transluminal coronary angioplasty (PTCA). The effects of the time delay between balloon inflations during PTCA on ischemic preconditioning were investigated in 48 patients with chronic s...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::A 66-year-old man was admitted with distal edema of his right leg. He had undergone radical prostatectomy and pelvic lymphadenectomy for prostatic cancer 23 days previously. Abdominal computed tomography (CT) showed a lymphocyst (4.5 x 3.0 cm) along the right pelvic wall compressing the right external iliac vein. CT w...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract::Both coronary perforation and aneurysms associated with sirolimus-eluting stent (SES) implantations are uncommon complications. We describe an unusual case of a coronary aneurysm associated with a coronary perforation after SES implantation. Although their pathogenesis has not yet been completely elucidated, some tech...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2008.09.013
更新日期:2009-08-01 00:00:00
abstract::To clarify the effects of mitral obstruction on left ventricular (LV) diastolic blood filling, 15 patients with tight mitral stenosis (each mitral valve area was less than 1.5 cm2) were studied. Each selected patient underwent successful percutaneous transluminal mitral commissurotomy (PTMC), which resulted in a 1.5 f...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::A 56-year-old man with old anteroseptal myocardial infarction was admitted to treat a gradually expanding coronary aneurysm. Coronary angiography demonstrated the aneurysm and delayed flow in the left coronary descending artery. The aneurysm was successfully treated with stenting. Technetium-99m-sestamibi single photo...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVES:This study assessed the side effects of nitroglycerin administration and their clinical significance. METHODS:Adverse reactions associated with sublingual nitroglycerin administration were investigated in 103 patients, 71 men and 32 women (mean age 56 +/- 11 years), 32 patients with coronary artery stenosis...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::From April 1987 to October 1989, 32 patients with mitral stenosis (MS) were treated, of whom percutaneous transvenous mitral commissurotomy (PTMC) was performed in 14. PTMC was indicated by the surgeons in 5 patients including 1) 2 patients who refused reoperation, 2) one with early gastric cancer, 3) one with severe ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Anticoagulant therapy is used for preventing cerebral infarction in patients with non-valvular atrial fibrillation (NVAF). However, in clinical practice, many patients with NVAF are not prescribed oral anticoagulants (OACs). In this study, we retrospectively investigated the prescription status of OACs at th...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.11.002
更新日期:2020-05-01 00:00:00