Pre-SMA actively engages in conflict processing in human: a combined study of epicortical ERPs and direct cortical stimulation.

Abstract:

:Previous non-invasive studies have proposed that the deeply seated region of the medial frontal cortex engages in conflict processing in humans, but its core region has remained to be elucidated. By means of direct cortical stimulation, which excels other techniques in temporal and spatial resolutions and in the capacity of producing transient, functional impairment even in the deeply located cortices, we attempted to obtain direct evidence that the pre-supplementary motor area (pre-SMA) actively engages in conflict processing. Subject was a patient with right frontal lobe epilepsy who underwent invasive presurgical evaluation with subdural electrodes placed on the medial and lateral frontal cortices. During a conflict task--modified Eriksen flanker task, direct cortical stimulation was delivered time-locked to the task at the inferior part of the medial superior frontal gyrus (inferior medial SFG), the superior part of the medial SFG, and the middle frontal gyrus. By adopting the session of sham stimulation that was employed as a within-block control, event-related potentials (ERPs) were recorded from the medial and lateral frontal cortices. The inferior medial SFG showed a significant ERP difference between trials with more and less conflict, while the other frontal cortices did not. Among the three stimulus sites, only stimulation of the inferior medial SFG significantly prolonged reaction time in trials with more conflict. Anatomically, the inferior medial SFG corresponded with the pre-SMA (Brodmann area 8). It was located 1-2 cm rostral to the vertical anterior commissure line where cortical stimulation elicited arrest of motion (the supplementary negative motor area). Functionally, this area corresponded to the dorso-rostral portion of the activation loci in previous neuroimaging studies focusing on conflict processing. By combining epicortical ERP recording and direct cortical stimulation in a human brain, this study, for the first time, presented one direct piece of evidence that the pre-SMA actively participates in conflict processing.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Usami K,Matsumoto R,Kunieda T,Shimotake A,Matsuhashi M,Miyamoto S,Fukuyama H,Takahashi R,Ikeda A

doi

10.1016/j.neuropsychologia.2013.02.002

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

1011-7

issue

5

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(13)00044-4

journal_volume

51

pub_type

杂志文章
  • Left hemisphere representations of emotional facial expressions.

    abstract::Researchers have suggested that the right hemisphere is superior at processing emotional facial expressions because it contains stored perceptual 'templates' of facial expressions. We tested each hemisphere of a split-brain patient on two tasks involving emotional facial expressions. Both hemispheres performed equally...

    journal_title:Neuropsychologia

    pub_type: 临床试验,杂志文章

    doi:10.1016/0028-3932(95)00060-7

    authors: Stone VE,Nisenson L,Eliassen JC,Gazzaniga MS

    更新日期:1996-01-01 00:00:00

  • Developmental patterns of expressive language hemispheric lateralization in children, adolescents and adults using functional near-infrared spectroscopy.

    abstract::The development of language hemispheric specialization is not well understood in young children, especially regarding expressive language functions. In this study, we investigated age-related changes in expressive language lateralization patterns in a population of children (3-6 and 7-10 years old), adolescents (11-16...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2015.01.007

    authors: Paquette N,Lassonde M,Vannasing P,Tremblay J,González-Frankenberger B,Florea O,Béland R,Lepore F,Gallagher A

    更新日期:2015-02-01 00:00:00

  • Effects of anticaricaturing vs. caricaturing and their neural correlates elucidate a role of shape for face learning.

    abstract::To assess the role of shape information for unfamiliar face learning, we investigated effects of photorealistic spatial anticaricaturing and caricaturing on later face recognition. We assessed behavioural performance and event-related brain potential (ERP) correlates of recognition, using different images of anticaric...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2012.06.013

    authors: Schulz C,Kaufmann JM,Walther L,Schweinberger SR

    更新日期:2012-08-01 00:00:00

  • Understanding retrosplenial amnesia: insights from animal studies.

    abstract::Bilateral damage in the posterior cingulate region can induce anterograde amnesia. Identifying the potential contributions of the various areas within this heterogeneous region has, however, largely depended on animal research. Within the posterior cingulate region the retrosplenial cortex stands out by virtue of its ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuropsychologia.2009.09.030

    authors: Aggleton JP

    更新日期:2010-07-01 00:00:00

  • Lexical and syntactic representations in the brain: an fMRI investigation with multi-voxel pattern analyses.

    abstract::Work in theoretical linguistics and psycholinguistics suggests that human linguistic knowledge forms a continuum between individual lexical items and abstract syntactic representations, with most linguistic representations falling between the two extremes and taking the form of lexical items stored together with the s...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2011.09.014

    authors: Fedorenko E,Nieto-Castañon A,Kanwisher N

    更新日期:2012-03-01 00:00:00

  • Pitch expertise is not created equal: Cross-domain effects of musicianship and tone language experience on neural and behavioural discrimination of speech and music.

    abstract::Psychophysiological evidence supports a music-language association, such that experience in one domain can impact processing required in the other domain. We investigated the bidirectionality of this association by measuring event-related potentials (ERPs) in native English-speaking musicians, native tone language (Ca...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2015.03.019

    authors: Hutka S,Bidelman GM,Moreno S

    更新日期:2015-05-01 00:00:00

  • Body and movement: consciousness in the parietal lobes.

    abstract::A critical issue related to the notion of identity concerns our ability to discriminate between internally and externally generated stimuli. This basic mechanism likely relies on perceptual and motor information, and requires that both motor plans and the resulting activity be continuously mapped on a reliable body re...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2009.10.008

    authors: Daprati E,Sirigu A,Nico D

    更新日期:2010-02-01 00:00:00

  • Subclassification of non-pathological left-handers poses problems for theories of handedness.

    abstract::The throwing performance of 104 right-handers, and 96 left-handers with inconsistent and consistent hand preferences, as classified by the procedure used by Ponton (Neuropsychologia 25, 305-311, 1987), was examined. Left-handers with inconsistent hand preference write with the left, tap faster with the left, and perfo...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(90)90021-f

    authors: Peters M

    更新日期:1990-01-01 00:00:00

  • Minimal humanity cues induce neural empathic reactions towards non-human entities.

    abstract::The present study tested whether the attribution of humanness by means of a minimal humanity cue is sufficient for the occurrence of empathic neural reactions towards non-human entities that are painfully stimulated. Vegetables have been used as a control condition to explore empathy towards humans' pain before. In th...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2016.06.004

    authors: Vaes J,Meconi F,Sessa P,Olechowski M

    更新日期:2016-08-01 00:00:00

  • Factor analysis and the cerebral hemispheres: temporal, occipital and frontal functions.

    abstract::Three experiments are reported that use a number of lateralized tasks believed to draw on processes localized to the temporal, occipital or frontal lobes. Oblique factor analyses of the resultant asymmetries indicate the existence of nine lateralized functions, characterized as auditory lexical, facial figural, facial...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(92)90049-r

    authors: Boles DB

    更新日期:1992-11-01 00:00:00

  • Psychic trauma causing grossly reduced brain metabolism and cognitive deterioration.

    abstract::While amnesia and other cognitive disturbances are usually caused by structural brain damage, there are a few instances in which environmental stress may induce neuronal death in memory-sensitive brain regions such as the hippocampus. Here we report on a patient who, after a single brief exposure to an event reminding...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(97)00093-6

    authors: Markowitsch HJ,Kessler J,Van Der Ven C,Weber-Luxenburger G,Albers M,Heiss WD

    更新日期:1998-01-01 00:00:00

  • Context and crossover in unilateral neglect.

    abstract::Patients with left-neglect bisect horizontal lines to the right of true center. Their bisection bias is affected by line length, so that longer lines are bisected further to the right. Patients often crossover and bisect very short lines to the left of true center. We tested the hypothesis that the context in which li...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(01)00054-9

    authors: Ricci R,Chatterjee A

    更新日期:2001-01-01 00:00:00

  • Left hemisphere strategies in visual recognition, topographical orientation and time planning.

    abstract::Right hemisphere lesions are known to impair, in many cases, visual recognition and visuospatial orientation. We report here on the compensatory strategies used by a patient whose posterior part of the right hemisphere was either destroyed or visually deafferented. She presented a slight appreceptive agnosia, memory d...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(93)90039-3

    authors: Clarke S,Assal G,de Tribolet N

    更新日期:1993-02-01 00:00:00

  • Spatial field advantages for tactile line bisection as a function of hemispheric specialisation inferred from dichotic listening.

    abstract::Thirty left-ear advantaged (LEA) and 30 right-ear advantaged (REA) right-handed subjects performed tactile line bisection (TLB) in left and right spatial fields, and at midline. REA subjects were found to perform significantly better in the right spatial field than in the left and LEA subjects significantly better in ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(94)00107-z

    authors: Brodie EE,Pettigrew LE

    更新日期:1995-01-01 00:00:00

  • Improvement of deficits in mnemonic rhyme for multiplication in Japanese aphasics.

    abstract::Since Japanese learn the multiplication tables by means of mnemonic rhymes called kuku, i.e., via the auditory-speaking route, it is hypothesized that aphasics who have a deficit in kuku might relearn it via the visual-writing route. After having ordinary language therapy for more than 3 months, eight patients were ad...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(87)90032-7

    authors: Kashiwagi A,Kashiwagi T,Hasegawa T

    更新日期:1987-01-01 00:00:00

  • The effects of two matched memory tasks on concurrent finger tapping.

    abstract::In a dual task experiment, subjects were instructed to perform a single finger tapping task whilst either, concurrently memorizing words appearing randomly on a screen in front of them, or concurrently memorizing the positions of the words. Analysis of percentage change scores revealed a significant tapping hand by ta...

    journal_title:Neuropsychologia

    pub_type: 临床试验,杂志文章

    doi:10.1016/0028-3932(94)90074-4

    authors: Towell N,Burton A,Burton E

    更新日期:1994-01-01 00:00:00

  • The influence of mood on the processing of syntactic anomalies: evidence from P600.

    abstract::In several domains of psychology it has been shown that mood influences the way in which we process information. So far, little is known about the relation between mood and processes of language comprehension. In the present study we explore, whether, and if so how, mood affects the processing of syntactic anomalies i...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2010.08.001

    authors: Vissers CT,Virgillito D,Fitzgerald DA,Speckens AE,Tendolkar I,van Oostrom I,Chwilla DJ

    更新日期:2010-10-01 00:00:00

  • Selective attention to facial emotion and identity in schizophrenia.

    abstract::The selective attention to facial emotion and identity was investigated in 12 patients with schizophrenia and 12 healthy participants. Both patients and controls were required to perform two classification tasks (according either to identity or emotion). Two separate values for identity (person A/person B) and for emo...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(01)00114-2

    authors: Baudouin JY,Martin F,Tiberghien G,Verlut I,Franck N

    更新日期:2002-01-01 00:00:00

  • What goes through the gate? Exploring interference with visual feature binding.

    abstract::A series of experiments explored the mechanisms determining the encoding and storage of features and objects in visual working memory. We contrasted the effects of three types of visual suffix on cued recall of a display of colored shapes. The suffix was presented after the display and before the recall cue. The latte...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2010.11.030

    authors: Ueno T,Mate J,Allen RJ,Hitch GJ,Baddeley AD

    更新日期:2011-05-01 00:00:00

  • Parietal contributions to recollection: electrophysiological evidence from aging and patients with parietal lesions.

    abstract::There has been much recent investigation into the role of parietal cortex in memory retrieval. Proposed hypotheses include attention to internal memorial representations, an episodic working memory-type buffer, and an accumulator of retrieved memorial information. The current investigation used event-related potential...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2008.02.026

    authors: Ally BA,Simons JS,McKeever JD,Peers PV,Budson AE

    更新日期:2008-01-01 00:00:00

  • Rhythmic priming enhances the phonological processing of speech.

    abstract::While natural speech does not possess the same degree of temporal regularity found in music, there is recent evidence to suggest that temporal regularity enhances speech processing. The aim of this experiment was to examine whether speech processing would be enhanced by the prior presentation of a rhythmical prime. We...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2012.07.018

    authors: Cason N,Schön D

    更新日期:2012-09-01 00:00:00

  • Sensitivity to structure in action sequences: An infant event-related potential study.

    abstract::Infants are sensitive to structure and patterns within continuous streams of sensory input. This sensitivity relies on statistical learning, the ability to detect predictable regularities in spatial and temporal sequences. Recent evidence has shown that infants can detect statistical regularities in action sequences t...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2017.05.007

    authors: Monroy CD,Gerson SA,Domínguez-Martínez E,Kaduk K,Hunnius S,Reid V

    更新日期:2019-03-18 00:00:00

  • Longitudinal evidence that reduced hemispheric encoding/retrieval asymmetry predicts episodic-memory impairment in aging.

    abstract::The HERA (Hemispheric Encoding/Retrieval Asymmetry) model captures hemispheric lateralization of prefrontal cortex (PFC) brain activity during memory encoding and retrieval. Reduced HERA has been observed in cross-sectional aging studies, but there is no longitudinal evidence, to our knowledge, on age-related changes ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2019.107329

    authors: Johansson J,Salami A,Lundquist A,Wåhlin A,Andersson M,Nyberg L

    更新日期:2020-02-03 00:00:00

  • Chronic anosognosia: a case report and theoretical account.

    abstract::Unawareness of motor disorders (anosognosia) has often been reported after brain lesions, and it has been considered a temporary condition common in the acute and post-acute phases. The presence of anosognosia in a chronic phase (i.e. lasting more than few weeks) is a rare occurrence, thought to be the result of reaso...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(02)00054-4

    authors: Cocchini G,Beschin N,Sala SD

    更新日期:2002-01-01 00:00:00

  • Disruption to higher order processes in Friedreich ataxia.

    abstract::Friedreich ataxia (FRDA), the most common of the genetically inherited ataxias, is characterised by ocular motor deficits largely reflecting disruption to brainstem-cerebellar circuitry. These deficits include fixation instability, saccadic dysmetria, disrupted pursuit, and vestibular abnormalities. Whether higher ord...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2009.09.009

    authors: Fielding J,Corben L,Cremer P,Millist L,White O,Delatycki M

    更新日期:2010-01-01 00:00:00

  • The use of conditional inference to reduce prediction error--a mismatch negativity (MMN) study.

    abstract::The brain uses regularities in the sound environment to build inference models predicting the most likely attributes of subsequent sounds. When the inference model fails, a prediction-error signal (the mismatch negativity or MMN) is generated. This study is designed to explore the capacity to use information about whe...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2010.06.009

    authors: Todd J,Robinson J

    更新日期:2010-08-01 00:00:00

  • Face-name associative memory performance is related to amyloid burden in normal elderly.

    abstract::Cerebral amyloid beta (Aβ) deposition occurs in a substantial fraction of cognitively normal (CN) older individuals. However, it has been difficult to reliably detect evidence of amyloid-related cognitive alterations in CN using standard neuropsychological measures. We sought to determine whether a highly demanding fa...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2011.06.006

    authors: Rentz DM,Amariglio RE,Becker JA,Frey M,Olson LE,Frishe K,Carmasin J,Maye JE,Johnson KA,Sperling RA

    更新日期:2011-07-01 00:00:00

  • Speechreading circuits in people born deaf.

    abstract::In hearing people, silent speechreading generates bilateral activation in superior temporal regions specialised for the perception of auditory speech [Science 276 (1997) 593; Neuroreport 11 (2000) 1729; Proceedings of the Royal Society London B 268 (2001) 451]. In the present study, FMRI data were collected from deaf ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(01)00180-4

    authors: MacSweeney M,Calvert GA,Campbell R,McGuire PK,David AS,Williams SC,Woll B,Brammer MJ

    更新日期:2002-01-01 00:00:00

  • Shedding new light on representational neglect: The importance of dissociating visual and spatial components.

    abstract::Over the last decade, many studies have demonstrated that visuospatial working memory (VSWM) can be divided into two subsystems, dealing respectively with spatial and visual information. A similar dissociation has been observed in brain-damaged patients without neglect for mental imagery skills. The first aim of the p...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2016.02.006

    authors: Wansard M,Meulemans T,Geurten M

    更新日期:2016-04-01 00:00:00

  • Sequential audiovisual interactions during speech perception: a whole-head MEG study.

    abstract::Using whole-head magnetoencephalography (MEG), audiovisual (AV) interactions during speech perception (/ta/- and /pa/-syllables) were investigated in 20 subjects. Congruent AV events served as the 'standards' of an oddball design. The deviants encompassed incongruent /ta/-/pa/ configurations differing from the standar...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2006.09.019

    authors: Hertrich I,Mathiak K,Lutzenberger W,Menning H,Ackermann H

    更新日期:2007-03-25 00:00:00