University-Based Outbreaks of Meningococcal Disease Caused by Serogroup B, United States, 2013-2018.

Abstract:

:We reviewed university-based outbreaks of meningococcal disease caused by serogroup B and vaccination responses in the United States in the years following serogroup B meningococcal (MenB) vaccine availability. Ten university-based outbreaks occurred in 7 states during 2013-2018, causing a total of 39 cases and 2 deaths. Outbreaks occurred at universities with 3,600-35,000 undergraduates. Outbreak case counts ranged from 2 to 9 cases; outbreak duration ranged from 0 to 376 days. All 10 universities implemented MenB vaccination: 3 primarily used MenB-FHbp and 7 used MenB-4C. Estimated first-dose vaccination coverage ranged from 14% to 98%. In 5 outbreaks, additional cases occurred 6-259 days following MenB vaccination initiation. Although it is difficult to predict outbreak trajectories and evaluate the effects of public health response measures, achieving high MenB vaccination coverage is crucial to help protect at-risk persons during outbreaks of meningococcal disease caused by this serogroup.

journal_name

Emerg Infect Dis

authors

Soeters HM,McNamara LA,Blain AE,Whaley M,MacNeil JR,Hariri S,Mbaeyi SA,Serogroup B Meningococcal Disease University Outbreak Group.

doi

10.3201/eid2503.181574

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

434-440

issue

3

eissn

1080-6040

issn

1080-6059

journal_volume

25

pub_type

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