Abstract:
:We reviewed university-based outbreaks of meningococcal disease caused by serogroup B and vaccination responses in the United States in the years following serogroup B meningococcal (MenB) vaccine availability. Ten university-based outbreaks occurred in 7 states during 2013-2018, causing a total of 39 cases and 2 deaths. Outbreaks occurred at universities with 3,600-35,000 undergraduates. Outbreak case counts ranged from 2 to 9 cases; outbreak duration ranged from 0 to 376 days. All 10 universities implemented MenB vaccination: 3 primarily used MenB-FHbp and 7 used MenB-4C. Estimated first-dose vaccination coverage ranged from 14% to 98%. In 5 outbreaks, additional cases occurred 6-259 days following MenB vaccination initiation. Although it is difficult to predict outbreak trajectories and evaluate the effects of public health response measures, achieving high MenB vaccination coverage is crucial to help protect at-risk persons during outbreaks of meningococcal disease caused by this serogroup.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Soeters HM,McNamara LA,Blain AE,Whaley M,MacNeil JR,Hariri S,Mbaeyi SA,Serogroup B Meningococcal Disease University Outbreak Group.doi
10.3201/eid2503.181574subject
Has Abstractpub_date
2019-03-01 00:00:00pages
434-440issue
3eissn
1080-6040issn
1080-6059journal_volume
25pub_type
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