Abstract:
:An outbreak of Q fever occurred in South Wales, United Kingdom, from July 15 through September 30, 2002. To investigate the outbreak a cohort and nested case-control study of persons who had worked at a cardboard manufacturing plant was conducted. The cohort included 282 employees and subcontractors, of whom 253 (90%) provided blood samples and 214 (76%) completed questionnaires. Ninety-five cases of acute Q fever were identified. The epidemic curve and other data suggested an outbreak source likely occurred August 5-9, 2002. Employees in the factory's offices were at greatest risk for infection (odds ratio 3.46; 95% confidence interval 1.38-9.06). The offices were undergoing renovation work around the time of likely exposure and contained straw board that had repeatedly been drilled. The outbreak may have been caused by aerosolization of Coxiella burnetii spore-like forms during drilling into contaminated straw board.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
van Woerden HC,Mason BW,Nehaul LK,Smith R,Salmon RL,Healy B,Valappil M,Westmoreland D,de Martin S,Evans MR,Lloyd G,Hamilton-Kirkwood M,Williams NSdoi
10.3201/eid1007.030536subject
Has Abstractpub_date
2004-07-01 00:00:00pages
1282-9issue
7eissn
1080-6040issn
1080-6059journal_volume
10pub_type
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